Rui Xu

Rui Xu, Yong Luo, Bo Du et al.

Convolutional neural networks (CNNs) have been demonstrated to be highly effective in the field of pulmonary nodule detection. However, existing CNN based pulmonary nodule detection methods lack the ability to capture long-range dependencies, which is vital for global information extraction. In computer vision tasks, non-local operations have been widely utilized, but the computational cost could be very high for 3D computed tomography (CT) images. To address this issue, we propose a long short slice-aware network (LSSANet) for the detection of pulmonary nodules. In particular, we develop a new non-local mechanism termed long short slice grouping (LSSG), which splits the compact non-local embeddings into a short-distance slice grouped one and a long-distance slice grouped counterpart. This not only reduces the computational burden, but also keeps long-range dependencies among any elements across slices and in the whole feature map. The proposed LSSG is easy-to-use and can be plugged into many pulmonary nodule detection networks. To verify the performance of LSSANet, we compare with several recently proposed and competitive detection approaches based on 2D/3D CNN. Promising evaluation results on the large-scale PN9 dataset demonstrate the effectiveness of our method. Code is at https://github.com/Ruixxxx/LSSANet.

Rui Xu, Zhi Liu, Yong Luo et al.

Lung cancer is the leading cause of cancer death worldwide. The best solution for lung cancer is to diagnose the pulmonary nodules in the early stage, which is usually accomplished with the aid of thoracic computed tomography (CT). As deep learning thrives, convolutional neural networks (CNNs) have been introduced into pulmonary nodule detection to help doctors in this labor-intensive task and demonstrated to be very effective. However, the current pulmonary nodule detection methods are usually domain-specific, and cannot satisfy the requirement of working in diverse real-world scenarios. To address this issue, we propose a slice grouped domain attention (SGDA) module to enhance the generalization capability of the pulmonary nodule detection networks. This attention module works in the axial, coronal, and sagittal directions. In each direction, we divide the input feature into groups, and for each group, we utilize a universal adapter bank to capture the feature subspaces of the domains spanned by all pulmonary nodule datasets. Then the bank outputs are combined from the perspective of domain to modulate the input group. Extensive experiments demonstrate that SGDA enables substantially better multi-domain pulmonary nodule detection performance compared with the state-of-the-art multi-domain learning methods.

Rui Xu, Yong Luo, Bo Du

Cross-domain pulmonary nodule detection suffers from performance degradation due to a large shift of data distributions between the source and target domain. Besides, considering the high cost of medical data annotation, it is often assumed that the target images are unlabeled. Existing approaches have made much progress for this unsupervised domain adaptation setting. However, this setting is still rarely plausible in medical applications since the source medical data are often not accessible due to privacy concerns. This motivates us to propose a Source-free Unsupervised cross-domain method for Pulmonary nodule detection (SUP), named Instance-level Contrastive Instruction fine-tuning framework (ICI). It first adapts the source model to the target domain by utilizing instance-level contrastive learning. Then the adapted model is trained in a teacher-student interaction manner, and a weighted entropy loss is incorporated to further improve the accuracy. We establish a benchmark by adapting a pre-trained source model to three popular datasets for pulmonary nodule detection. To the best of our knowledge, this represents the first exploration of source-free unsupervised domain adaptation in medical image object detection. Our extensive evaluations reveal that SUP-ICI substantially surpasses existing state-of-the-art approaches, achieving FROC score improvements ranging from 8.98% to 16.05%. This breakthrough not only sets a new precedent for domain adaptation techniques in medical imaging but also significantly advances the field toward overcoming challenges posed by data privacy and availability. Code: https://github.com/Ruixxxx/SFUDA.

Huangbiao Xu, Huanqi Wu, Xiao Ke et al.

Multimodal Action Quality Assessment (AQA) has recently emerged as a promising paradigm. By leveraging complementary information across shared contextual cues, it enhances the discriminative evaluation of subtle intra-class variations in highly similar action sequences. However, partial modalities are frequently unavailable at the inference stage in reality. The absence of any modality often renders existing multimodal models inoperable. Furthermore, it triggers catastrophic performance degradation due to interruptions in cross-modal interactions. To address this issue, we propose a novel Missing Completion Framework with Mixture of Experts (MCMoE) that unifies unimodal and joint representation learning in single-stage training. Specifically, we propose an adaptive gated modality generator that dynamically fuses available information to reconstruct missing modalities. We then design modality experts to learn unimodal knowledge and dynamically mix the knowledge of all experts to extract cross-modal joint representations. With a mixture of experts, missing modalities are further refined and complemented. Finally, in the training phase, we mine the complete multimodal features and unimodal expert knowledge to guide modality generation and generation-based joint representation extraction. Extensive experiments demonstrate that our MCMoE achieves state-of-the-art results in both complete and incomplete multimodal learning on three public AQA benchmarks. Code is available at https://github.com/XuHuangbiao/MCMoE.