Siying Liu

Wen-Yan Lin, Siying Liu, Bing Tian Dai et al.

Most classifiers rely on discriminative boundaries that separate instances of each class from everything else. We argue that discriminative boundaries are counter-intuitive as they define semantics by what-they-are-not; and should be replaced by generative classifiers which define semantics by what-they-are. Unfortunately, generative classifiers are significantly less accurate. This may be caused by the tendency of generative models to focus on easy to model semantic generative factors and ignore non-semantic factors that are important but difficult to model. We propose a new generative model in which semantic factors are accommodated by shell theory's hierarchical generative process and non-semantic factors by an instance specific noise term. We use the model to develop a classification scheme which suppresses the impact of noise while preserving semantic cues. The result is a surprisingly accurate generative classifier, that takes the form of a modified nearest-neighbor algorithm; we term it distance classification. Unlike discriminative classifiers, a distance classifier: defines semantics by what-they-are; is amenable to incremental updates; and scales well with the number of classes.

Siying Liu, Zikai Wang, Hanle Zheng et al.

RGB-Event tracking has become a promising trend in visual object tracking to leverage the complementary strengths of both RGB images and dynamic spike events for improved performance. However, existing artificial neural networks (ANNs) struggle to fully exploit the sparse and asynchronous nature of event streams. Recent efforts toward hybrid architectures combining ANNs and spiking neural networks (SNNs) have emerged as a promising solution in RGB-Event perception, yet effectively fusing features across heterogeneous paradigms remains a challenge. In this work, we propose ISTASTrack, the first transformer-based \textbf{A}NN-\textbf{S}NN hybrid \textbf{Track}er equipped with \textbf{ISTA} adapters for RGB-Event tracking. The two-branch model employs a vision transformer to extract spatial context from RGB inputs and a spiking transformer to capture spatio-temporal dynamics from event streams. To bridge the modality and paradigm gap between ANN and SNN features, we systematically design a model-based ISTA adapter for bidirectional feature interaction between the two branches, derived from sparse representation theory by unfolding the iterative shrinkage thresholding algorithm. Additionally, we incorporate a temporal downsampling attention module within the adapter to align multi-step SNN features with single-step ANN features in the latent space, improving temporal fusion. Experimental results on RGB-Event tracking benchmarks, such as FE240hz, VisEvent, COESOT, and FELT, have demonstrated that ISTASTrack achieves state-of-the-art performance while maintaining high energy efficiency, highlighting the effectiveness and practicality of hybrid ANN-SNN designs for robust visual tracking. The code is publicly available at https://github.com/lsying009/ISTASTrack.git.

Siying Liu, Pier Luigi Dragotti

Deep neural networks for event-based video reconstruction often suffer from a lack of interpretability and have high memory demands. A lightweight network called CISTA-LSTC has recently been introduced showing that high-quality reconstruction can be achieved through the systematic design of its architecture. However, its modelling assumption that input signals and output reconstructed frame share the same sparse representation neglects the displacement caused by motion. To address this, we propose warping the input intensity frames and sparse codes to enhance reconstruction quality. A CISTA-Flow network is constructed by integrating a flow network with CISTA-LSTC for motion compensation. The system relies solely on events, in which predicted flow aids in reconstruction and then reconstructed frames are used to facilitate flow estimation. We also introduce an iterative training framework for this combined system. Results demonstrate that our approach achieves state-of-the-art reconstruction accuracy and simultaneously provides reliable dense flow estimation. Furthermore, our model exhibits flexibility in that it can integrate different flow networks, suggesting its potential for further performance enhancement.

Siying Liu, Shisheng Zhang, Indu Bala

Large language models (LLMs) are increasingly applied in biomedical domains, yet their reliability in drug-safety prediction remains underexplored. In this work, we investigate whether LLMs incorporate socio-demographic information into adverse event (AE) predictions, despite such attributes being clinically irrelevant. Using structured data from the United States Food and Drug Administration Adverse Event Reporting System (FAERS) and a persona-based evaluation framework, we assess two state-of-the-art models, ChatGPT-4o and Bio-Medical-Llama-3.8B, across diverse personas defined by education, marital status, employment, insurance, language, housing stability, and religion. We further evaluate performance across three user roles (general practitioner, specialist, patient) to reflect real-world deployment scenarios where commercial systems often differentiate access by user type. Our results reveal systematic disparities in AE prediction accuracy. Disadvantaged groups (e.g., low education, unstable housing) were frequently assigned higher predicted AE likelihoods than more privileged groups (e.g., postgraduate-educated, privately insured). Beyond outcome disparities, we identify two distinct modes of bias: explicit bias, where incorrect predictions directly reference persona attributes in reasoning traces, and implicit bias, where predictions are inconsistent, yet personas are not explicitly mentioned. These findings expose critical risks in applying LLMs to pharmacovigilance and highlight the urgent need for fairness-aware evaluation protocols and mitigation strategies before clinical deployment.

Meng Wang, Tian Lin, Aidi Lin et al.

Previous foundation models for fundus images were pre-trained with limited disease categories and knowledge base. Here we introduce a knowledge-rich vision-language model (RetiZero) that leverages knowledge from more than 400 fundus diseases. For RetiZero's pretraining, we compiled 341,896 fundus images paired with texts, sourced from public datasets, ophthalmic literature, and online resources, encompassing a diverse range of diseases across multiple ethnicities and countries. RetiZero exhibits remarkable performance in several downstream tasks, including zero-shot disease recognition, image-to-image retrieval, AI-assisted clinical diagnosis,few-shot fine-tuning, and internal- and cross-domain disease identification. In zero-shot scenarios, RetiZero achieves Top-5 accuracies of 0.843 for 15 diseases and 0.756 for 52 diseases. For image retrieval, it achieves Top-5 scores of 0.950 and 0.886 for the same sets, respectively. AI-assisted clinical diagnosis results show that RetiZero's Top-3 zero-shot performance surpasses the average of 19 ophthalmologists from Singapore, China, and the United States. RetiZero substantially enhances clinicians' accuracy in diagnosing fundus diseases, in particularly rare ones. These findings underscore the value of integrating the RetiZero into clinical settings, where various fundus diseases are encountered.

Shuokang Huang, Kaihan Li, Di You et al.

WiFi-based human sensing has exhibited remarkable potential to analyze user behaviors in a non-intrusive and device-free manner, benefiting applications as diverse as smart homes and healthcare. However, most previous works focus on single-user sensing, which has limited practicability in scenarios involving multiple users. Although recent studies have begun to investigate WiFi-based multi-user sensing, there remains a lack of benchmark datasets to facilitate reproducible and comparable research. To bridge this gap, we present WiMANS, to our knowledge, the first dataset for multi-user sensing based on WiFi. WiMANS contains over 9.4 hours of dual-band WiFi Channel State Information (CSI), as well as synchronized videos, monitoring simultaneous activities of multiple users. We exploit WiMANS to benchmark the performance of state-of-the-art WiFi-based human sensing models and video-based models, posing new challenges and opportunities for future work. We believe WiMANS can push the boundaries of current studies and catalyze the research on WiFi-based multi-user sensing.

Huajian Huang, Wen-Yan Lin, Siying Liu et al.

SLAM (Simultaneous Localization And Mapping) seeks to provide a moving agent with real-time self-localization. To achieve real-time speed, SLAM incrementally propagates position estimates. This makes SLAM fast but also makes it vulnerable to local pose estimation failures. As local pose estimation is ill-conditioned, local pose estimation failures happen regularly, making the overall SLAM system brittle. This paper attempts to correct this problem. We note that while local pose estimation is ill-conditioned, pose estimation over longer sequences is well-conditioned. Thus, local pose estimation errors eventually manifest themselves as mapping inconsistencies. When this occurs, we save the current map and activate two new SLAM threads. One processes incoming frames to create a new map and the other, recovery thread, backtracks to link new and old maps together. This creates a Dual-SLAM framework that maintains real-time performance while being robust to local pose estimation failures. Evaluation on benchmark datasets shows Dual-SLAM can reduce failures by a dramatic $88\%$.

Wen-Yan Lin, Siying Liu, Jian-Huang Lai et al.

Many high dimensional vector distances tend to a constant. This is typically considered a negative "contrast-loss" phenomenon that hinders clustering and other machine learning techniques. We reinterpret "contrast-loss" as a blessing. Re-deriving "contrast-loss" using the law of large numbers, we show it results in a distribution's instances concentrating on a thin "hyper-shell". The hollow center means apparently chaotically overlapping distributions are actually intrinsically separable. We use this to develop distribution-clustering, an elegant algorithm for grouping of data points by their (unknown) underlying distribution. Distribution-clustering, creates notably clean clusters from raw unlabeled data, estimates the number of clusters for itself and is inherently robust to "outliers" which form their own clusters. This enables trawling for patterns in unorganized data and may be the key to enabling machine intelligence.