Junxi Chen

Junhao Dong, Junxi Chen, Xiaohua Xie et al.

Deep learning techniques have achieved superior performance in computer-aided medical image analysis, yet they are still vulnerable to imperceptible adversarial attacks, resulting in potential misdiagnosis in clinical practice. Oppositely, recent years have also witnessed remarkable progress in defense against these tailored adversarial examples in deep medical diagnosis systems. In this exposition, we present a comprehensive survey on recent advances in adversarial attacks and defenses for medical image analysis with a systematic taxonomy in terms of the application scenario. We also provide a unified framework for different types of adversarial attack and defense methods in the context of medical image analysis. For a fair comparison, we establish a new benchmark for adversarially robust medical diagnosis models obtained by adversarial training under various scenarios. To the best of our knowledge, this is the first survey paper that provides a thorough evaluation of adversarially robust medical diagnosis models. By analyzing qualitative and quantitative results, we conclude this survey with a detailed discussion of current challenges for adversarial attack and defense in medical image analysis systems to shed light on future research directions. Code is available on \href{https://github.com/tomvii/Adv_MIA}{\color{red}{GitHub}}.

Junxi Chen, Junhao Dong, Xiaohua Xie et al.

Adversarial training (AT) is considered the most effective defense against adversarial attacks. However, a recent study revealed that \(\ell_{\infty}\)-norm adversarial training (\(\ell_{\infty}\)-AT) will also induce unevenly distributed input gradients, which is called the inequality phenomenon. This phenomenon makes the \(\ell_{\infty}\)-norm adversarially trained model more vulnerable than the standard-trained model when high-attribution or randomly selected pixels are perturbed, enabling robust and practical black-box attacks against \(\ell_{\infty}\)-adversarially trained models. In this paper, we propose a simple yet effective method called Input Gradient Distillation (IGD) to release the inequality phenomenon in $\ell_{\infty}$-AT. IGD distills the standard-trained teacher model's equal decision pattern into the $\ell_{\infty}$-adversarially trained student model by aligning input gradients of the student model and the standard-trained model with the Cosine Similarity. Experiments show that IGD can mitigate the inequality phenomenon and its threats while preserving adversarial robustness. Compared to vanilla $\ell_{\infty}$-AT, IGD reduces error rates against inductive noise, inductive occlusion, random noise, and noisy images in ImageNet-C by up to 60\%, 16\%, 50\%, and 21\%, respectively. Other than empirical experiments, we also conduct a theoretical analysis to explain why releasing the inequality phenomenon can improve such robustness and discuss why the severity of the inequality phenomenon varies according to the dataset's image resolution. Our code is available at https://github.com/fhdnskfbeuv/Inuput-Gradient-Distillation

Junxi Chen, Junhao Dong, Xiaohua Xie

Recently, many studies utilized adversarial examples (AEs) to raise the cost of malicious image editing and copyright violation powered by latent diffusion models (LDMs). Despite their successes, a few have studied the surrogate model they used to generate AEs. In this paper, from the perspective of adversarial transferability, we investigate how the surrogate model's property influences the performance of AEs for LDMs. Specifically, we view the time-step sampling in the Monte-Carlo-based (MC-based) adversarial attack as selecting surrogate models. We find that the smoothness of surrogate models at different time steps differs, and we substantially improve the performance of the MC-based AEs by selecting smoother surrogate models. In the light of the theoretical framework on adversarial transferability in image classification, we also conduct a theoretical analysis to explain why smooth surrogate models can also boost AEs for LDMs.