Bin Hu

JaeWoong Shin, Jeongun Ryu, Aaron Valero Puche et al.

Pathologists routinely alternate between different magnifications when examining Whole-Slide Images, allowing them to evaluate both broad tissue morphology and intricate cellular details to form comprehensive diagnoses. However, existing deep learning-based cell detection models struggle to replicate these behaviors and learn the interdependent semantics between structures at different magnifications. A key barrier in the field is the lack of datasets with multi-scale overlapping cell and tissue annotations. The OCELOT 2023 challenge was initiated to gather insights from the community to validate the hypothesis that understanding cell and tissue (cell-tissue) interactions is crucial for achieving human-level performance, and to accelerate the research in this field. The challenge dataset includes overlapping cell detection and tissue segmentation annotations from six organs, comprising 673 pairs sourced from 306 The Cancer Genome Atlas (TCGA) Whole-Slide Images with hematoxylin and eosin staining, divided into training, validation, and test subsets. Participants presented models that significantly enhanced the understanding of cell-tissue relationships. Top entries achieved up to a 7.99 increase in F1-score on the test set compared to the baseline cell-only model that did not incorporate cell-tissue relationships. This is a substantial improvement in performance over traditional cell-only detection methods, demonstrating the need for incorporating multi-scale semantics into the models. This paper provides a comparative analysis of the methods used by participants, highlighting innovative strategies implemented in the OCELOT 2023 challenge.

Bin Hu, Zongyang Zhang, Jianwei Liu et al.

Smart contracts are regarded as one of the most promising and appealing notions in blockchain technology. Their self-enforcing and event-driven features make some online activities possible without a trusted third party. Nevertheless, problems such as miscellaneous attacks, privacy leakage, and low processing rates pre-vent them from being widely applied. Various schemes and tools have been proposed to facilitate the construction and execution of secure smart contracts. However, a comprehensive survey for these proposals is absent, hindering new researchers and developers from a quick start. This paper surveys the literature and online resources on smart contract construction and execution over the period 2008-2020. We divide the studies into three categories: (1) design paradigms that give examples and patterns on contract construction, (2) design tools that facilitate the development of secure smart contracts, and (3) extensions and alternatives that improve the privacy or efficiency of the system. We start by grouping the relevant construction schemes into the first two categories. We then review the execution mechanisms in the last category and further divide the state-of-the-art solutions into three classes: private contracts with extra tools, off-chain channels, and extensions on core functionalities. Finally, we summarize several challenges and identify future research directions toward developing secure, privacy-preserving, and efficient smart contracts.