Qiang Guan

Pegah Ahadian, Mingrui Yang, Sixu Chen et al.

Knee osteoarthritis frequently exhibits discordance between structural damage observed in imaging and patient-reported symptoms such as pain. This mismatch complicates clinical interpretation and patient stratification and remains insufficiently modeled in existing decision support systems. We propose a discordance aware multimodal framework that combines machine learning prediction models with a tool grounded multi agent reasoning system. Using baseline data from the FNIH Osteoarthritis Biomarkers Consortium, we trained multimodal models to predict two progression tasks, joint space loss only progression versus non progression, and pain only progression versus non progression. The predictive system integrates three modality specific experts: a CatBoost tabular model using demographic, radiographic, MRI-derived scalar, and biomarker features; MRI image embeddings extracted using a ResNet18 backbone; and Xray embeddings derived from the same architecture. Expert predictions are fused using a stacking ensemble. Residual based models estimate expected pain from structural features, enabling the computation of a pain structure discordance score between observed and expected symptoms. A multi-agent reasoning layer interprets these signals to assign clinically interpretable OA phenotypes and generate phenotype specific management recommendations.

Pegah Ahadian, Wei Xu, Sherry Wang et al.

Sleep disorders have a major impact on both lifestyle and health. Effective sleep disorder prediction from lifestyle and physiological data can provide essential details for early intervention. This research utilizes three deep time series models and facilitates them with explainability approaches for sleep disorder prediction. Specifically, our approach adopts Temporal Convolutional Networks (TCN), Long Short-Term Memory (LSTM) for time series data analysis, and Temporal Fusion Transformer model (TFT). Meanwhile, the temporal attention mechanism and counterfactual explanation with SHapley Additive exPlanations (SHAP) approach are employed to ensure dependable, accurate, and interpretable predictions. Finally, using a large dataset of sleep health measures, our evaluation demonstrates the effect of our method in predicting sleep disorders.

Pegah Ahadian, Yunhe Feng, Karl Kosko et al.

Mathematics education, a crucial and basic field, significantly influences students' learning in related subjects and their future careers. Utilizing artificial intelligence to interpret and comprehend math problems in education is not yet fully explored. This is due to the scarcity of quality datasets and the intricacies of processing handwritten information. In this paper, we present a novel contribution to the field of mathematics education through the development of MNIST-Fraction, a dataset inspired by the renowned MNIST, specifically tailored for the recognition and understanding of handwritten math fractions. Our approach is the utilization of deep learning, specifically Convolutional Neural Networks (CNNs), for the recognition and understanding of handwritten math fractions to effectively detect and analyze fractions, along with their numerators and denominators. This capability is pivotal in calculating the value of fractions, a fundamental aspect of math learning. The MNIST-Fraction dataset is designed to closely mimic real-world scenarios, providing a reliable and relevant resource for AI-driven educational tools. Furthermore, we conduct a comprehensive comparison of our dataset with the original MNIST dataset using various classifiers, demonstrating the effectiveness and versatility of MNIST-Fraction in both detection and classification tasks. This comparative analysis not only validates the practical utility of our dataset but also offers insights into its potential applications in math education. To foster collaboration and further research within the computational and educational communities. Our work aims to bridge the gap in high-quality educational resources for math learning, offering a valuable tool for both educators and researchers in the field.

Hailong Jiang, Jianfeng Zhu, Yao Wan et al.

Intermediate Representations (IRs) play a critical role in compiler design and program analysis, yet their comprehension by Large Language Models (LLMs) remains underexplored. In this paper, we present an explorative empirical study evaluating the capabilities of six state-of-the-art LLMs: GPT-4, GPT-3, DeepSeek, Gemma 2, Llama 3, and Code Llama, in understanding IRs. Specifically, we assess model performance across four core tasks: control flow graph reconstruction, decompilation, code summarization, and execution reasoning. While LLMs exhibit competence in parsing IR syntax and identifying high-level structures, they consistently struggle with instruction-level reasoning, especially in control flow reasoning, loop handling, and dynamic execution. Common failure modes include misinterpreting branching instructions, omitting critical operations, and relying on heuristic reasoning rather than precise instruction-level logic. Our findings highlight the need for IR-specific enhancements in LLM design. We recommend fine-tuning on structured IR datasets and integrating control-flow-sensitive architectures to improve model effectiveness. All experimental data and source code are publicly available at

Shaolun Ruan, Yong Wang, Qiang Guan

Soft errors have become one of the major concerns for HPC applications, as those errors can result in seriously corrupted outcomes, such as silent data corruptions (SDCs). Prior studies on error resilience have studied the robustness of HPC applications. However, it is still difficult for program developers to identify potential vulnerability to soft errors. In this paper, we present Visilence, a novel visualization tool to visually analyze error vulnerability based on the control-flow graph generated from HPC applications. Visilence efficiently visualizes the affected program states under injected errors and presents the visual analysis of the most vulnerable parts of an application. We demonstrate the effectiveness of Visilence through a case study.

Shaolun Ruan, Yong Wang, Hailong Jiang et al.

Cloud systems are becoming increasingly powerful and complex. It is highly challenging to identify anomalous execution behaviors and pinpoint problems by examining the overwhelming intermediate results/states in complex application workflows. Domain scientists urgently need a friendly and functional interface to understand the quality of the computing services and the performance of their applications in real time. To meet these needs, we explore data generated by job schedulers and investigate general performance metrics (e.g., utilization of CPU, memory and disk I/O). Specifically, we propose an interactive visual analytics approach, BatchLens, to provide both providers and users of cloud service with an intuitive and effective way to explore the status of system batch jobs and help them conduct root-cause analysis of anomalous behaviors in batch jobs. We demonstrate the effectiveness of BatchLens through a case study on the public Alibaba bench workload trace datasets.

Shaolun Ruan, Yong Wang, Qiang Guan

State change comparison of multiple data items is often necessary in multiple application domains, such as medical science, financial engineering, sociology, biological science, etc. Slope graphs and grouped bar charts have been widely used to show a "before-and-after" story of different data states and indicate their changes. However, they visualize state changes as either slope or difference of bars, which has been proved less effective for quantitative comparison. Also, both visual designs suffer from visual clutter issues with an increasing number of data items. In this paper, we propose Intercept Graph, a novel visual design to facilitate effective interactive comparison of state changes. Specifically, a radial design is proposed to visualize the starting and ending states of each data item and the line segment length explicitly encodes the "state change". By interactively adjusting the radius of the inner circular axis, Intercept Graph can smoothly filter the large state changes and magnify the difference between similar state changes, mitigating the visual clutter issues and enhancing the effective comparison of state changes. We conducted a case study through comparing Intercept Graph with slope graphs and grouped bar charts on real datasets to demonstrate the effectiveness of Intercept Graph.

Yuxin Yang, Xitong Zhang, Qiang Guan et al.

Deep learning and data-driven approaches have shown great potential in scientific domains. The promise of data-driven techniques relies on the availability of a large volume of high-quality training datasets. Due to the high cost of obtaining data through expensive physical experiments, instruments, and simulations, data augmentation techniques for scientific applications have emerged as a new direction for obtaining scientific data recently. However, existing data augmentation techniques originating from computer vision, yield physically unacceptable data samples that are not helpful for the domain problems that we are interested in. In this paper, we develop new data augmentation techniques based on convolutional neural networks. Specifically, our generative models leverage different physics knowledge (such as governing equations, observable perception, and physics phenomena) to improve the quality of the synthetic data. To validate the effectiveness of our data augmentation techniques, we apply them to solve a subsurface seismic full-waveform inversion using simulated CO$_2$ leakage data. Our interest is to invert for subsurface velocity models associated with very small CO$_2$ leakage. We validate the performance of our methods using comprehensive numerical tests. Via comparison and analysis, we show that data-driven seismic imaging can be significantly enhanced by using our data augmentation techniques. Particularly, the imaging quality has been improved by 15% in test scenarios of general-sized leakage and 17% in small-sized leakage when using an augmented training set obtained with our techniques.

Xinyu Chen, Qiang Guan, Li-Ta Lo et al.

Convolutional Neural Networks(CNNs) are complex systems. They are trained so they can adapt their internal connections to recognize images, texts and more. It is both interesting and helpful to visualize the dynamics within such deep artificial neural networks so that people can understand how these artificial networks are learning and making predictions. In the field of scientific simulations, visualization tools like Paraview have long been utilized to provide insights and understandings. We present in situ TensorView to visualize the training and functioning of CNNs as if they are systems of scientific simulations. In situ TensorView is a loosely coupled in situ visualization open framework that provides multiple viewers to help users to visualize and understand their networks. It leverages the capability of co-processing from Paraview to provide real-time visualization during training and predicting phases. This avoid heavy I/O overhead for visualizing large dynamic systems. Only a small number of lines of codes are injected in TensorFlow framework. The visualization can provide guidance to adjust the architecture of networks, or compress the pre-trained networks. We showcase visualizing the training of LeNet-5 and VGG16 using in situ TensorView.