Quantum Approximate Optimization Algorithm (QAOA) and its variants exhibit immense potential in tackling combinatorial optimization challenges. However, their practical realization confronts a dilemma: the requisite circuit depth for satisfactory performance is problem-specific and often exceeds the maximum capability of current quantum devices. To address this dilemma, here we first analyze the convergence behavior of QAOA, uncovering the origins of this dilemma and elucidating the intricate relationship between the employed mixer Hamiltonian, the specific problem at hand, and the permissible maximum circuit depth. Harnessing this understanding, we introduce the Mixer Generator Network (MG-Net), a unified deep learning framework adept at dynamically formulating optimal mixer Hamiltonians tailored to distinct tasks and circuit depths. Systematic simulations, encompassing Ising models and weighted Max-Cut instances with up to 64 qubits, substantiate our theoretical findings, highlighting MG-Net's superior performance in terms of both approximation ratio and efficiency.
Mohammadmahdi Honarmand, Parnian Azizian, Aaron Kline et al.
Autism spectrum disorder (ASD) affects 1 in 31 US children, yet median age at diagnosis exceeds four years. Artificial intelligence pipelines that provide quantified diagnosis using easy to access observational data (e.g., home videos) could help with earlier diagnosis, and timely delivery of early treatments. We fine-tuned Gemini 2.5 Pro on 400 clinician-rated home videos with low-rank adaptation, training only on 30 behavioral features previously validated to produce reliable predictions when passed to various ML models. On 99 held-out children (49 ASD, 50 neurotypical), inter-rater reliability with clinicians (per-feature weighted Cohen's kappa) improved by 40% (p<0.001), with 27 of 28 evaluable features improving. As an emergent zero-shot capability, direct ASD diagnosis F1 improved by 53% (p<0.001), matching or exceeding clinician outcomes. Classifier-assisted pipelines using fine-tuned LLM-derived behavioral features matched clinician-scored inputs across all tested pathways and achieved 77% accuracy (95% CI: 68-85%) and an AUC of 86% (95% CI: 78-92%). Fine-tuned multimodal LLMs can serve as scalable behavioral feature extractors for use in autism assessment and diagnosis.
Topic models provide a flexible and principled framework for exploring hidden structure in high-dimensional co-occurrence data and are commonly used natural language processing (NLP) of text. In this paper, we design and implement a Java package, TopicModel4J, which contains 13 kinds of representative algorithms for fitting topic models. The TopicModel4J in the Java programming environment provides an easy-to-use interface for data analysts to run the algorithms, and allow to easily input and output data. In addition, this package provides a few unstructured text preprocessing techniques, such as splitting textual data into words, lowercasing the words, preforming lemmatization and removing the useless characters, URLs and stop words.
Chandrayee Basu, Qian Yang, David Hungerman et al.
With progress in enabling autonomous cars to drive safely on the road, it is time to start asking how they should be driving. A common answer is that they should be adopting their users' driving style. This makes the assumption that users want their autonomous cars to drive like they drive - aggressive drivers want aggressive cars, defensive drivers want defensive cars. In this paper, we put that assumption to the test. We find that users tend to prefer a significantly more defensive driving style than their own. Interestingly, they prefer the style they think is their own, even though their actual driving style tends to be more aggressive. We also find that preferences do depend on the specific driving scenario, opening the door for new ways of learning driving style preference.