Whole-Body Lesion Segmentation in 18F-FDG PET/CTJia Zhang, Yukun Huang, Zheng Zhang et al.
There has been growing research interest in using deep learning based method to achieve fully automated segmentation of lesion in Positron emission tomography computed tomography(PET CT) scans for the prognosis of various cancers. Recent advances in the medical image segmentation shows the nnUNET is feasible for diverse tasks. However, lesion segmentation in the PET images is not straightforward, because lesion and physiological uptake has similar distribution patterns. The Distinction of them requires extra structural information in the CT images. The present paper introduces a nnUNet based method for the lesion segmentation task. The proposed model is designed on the basis of the joint 2D and 3D nnUNET architecture to predict lesions across the whole body. It allows for automated segmentation of potential lesions. We evaluate the proposed method in the context of AutoPet Challenge, which measures the lesion segmentation performance in the metrics of dice score, false-positive volume and false-negative volume.
Enhancing Lesion Segmentation in PET/CT Imaging with Deep Learning and Advanced Data Preprocessing TechniquesJiayi Liu, Qiaoyi Xue, Youdan Feng et al.
The escalating global cancer burden underscores the critical need for precise diagnostic tools in oncology. This research employs deep learning to enhance lesion segmentation in PET/CT imaging, utilizing a dataset of 900 whole-body FDG-PET/CT and 600 PSMA-PET/CT studies from the AutoPET challenge III. Our methodical approach includes robust preprocessing and data augmentation techniques to ensure model robustness and generalizability. We investigate the influence of non-zero normalization and modifications to the data augmentation pipeline, such as the introduction of RandGaussianSharpen and adjustments to the Gamma transform parameter. This study aims to contribute to the standardization of preprocessing and augmentation strategies in PET/CT imaging, potentially improving the diagnostic accuracy and the personalized management of cancer patients. Our code will be open-sourced and available at https://github.com/jiayiliu-pku/DC2024.