Catalina Gómez

Catalina Gomez, Sue Min Cho, Shichang Ke et al.

Leveraging Artificial Intelligence (AI) in decision support systems has disproportionately focused on technological advancements, often overlooking the alignment between algorithmic outputs and human expectations. A human-centered perspective attempts to alleviate this concern by designing AI solutions for seamless integration with existing processes. Determining what information AI should provide to aid humans is vital, a concept underscored by explainable AI's efforts to justify AI predictions. However, how the information is presented, e.g., the sequence of recommendations and solicitation of interpretations, is equally crucial as complex interactions may emerge between humans and AI. While empirical studies have evaluated human-AI dynamics across domains, a common vocabulary for human-AI interaction protocols is lacking. To promote more deliberate consideration of interaction designs, we introduce a taxonomy of interaction patterns that delineate various modes of human-AI interactivity. We summarize the results of a systematic review of AI-assisted decision making literature and identify trends and opportunities in existing interactions across application domains from 105 articles. We find that current interactions are dominated by simplistic collaboration paradigms, leading to little support for truly interactive functionality. Our taxonomy offers a tool to understand interactivity with AI in decision-making and foster interaction designs for achieving clear communication, trustworthiness, and collaboration.

Benjamin D. Killeen, Anushri Suresh, Catalina Gomez et al.

Natural language offers a convenient, flexible interface for controlling robotic C-arm X-ray systems, making advanced functionality and controls accessible. However, enabling language interfaces requires specialized AI models that interpret X-ray images to create a semantic representation for reasoning. The fixed outputs of such AI models limit the functionality of language controls. Incorporating flexible, language-aligned AI models prompted through language enables more versatile interfaces for diverse tasks and procedures. Using a language-aligned foundation model for X-ray image segmentation, our system continually updates a patient digital twin based on sparse reconstructions of desired anatomical structures. This supports autonomous capabilities such as visualization, patient-specific viewfinding, and automatic collimation from novel viewpoints, enabling commands 'Focus in on the lower lumbar vertebrae.' In a cadaver study, users visualized, localized, and collimated structures across the torso using verbal commands, achieving 84% end-to-end success. Post hoc analysis of randomly oriented images showed our patient digital twin could localize 35 commonly requested structures to within 51.68 mm, enabling localization and isolation from arbitrary orientations. Our results demonstrate how intelligent robotic X-ray systems can incorporate physicians' expressed intent directly. While existing foundation models for intra-operative X-ray analysis exhibit failure modes, as they improve, they can facilitate highly flexible, intelligent robotic C-arms.

Catalina Gomez, Lalithkumar Seenivasan, Xinrui Zou et al.

Traditional surgical skill acquisition relies heavily on expert feedback, yet direct access is limited by faculty availability and variability in subjective assessments. While trainees can practice independently, the lack of personalized, objective, and quantitative feedback reduces the effectiveness of self-directed learning. Recent advances in computer vision and machine learning have enabled automated surgical skill assessment, demonstrating the feasibility of automatic competency evaluation. However, it is unclear whether such Artificial Intelligence (AI)-driven feedback can contribute to skill acquisition. Here, we examine the effectiveness of explainable AI (XAI)-generated feedback in surgical training through a human-AI study. We create a simulation-based training framework that utilizes XAI to analyze videos and extract surgical skill proxies related to primitive actions. Our intervention provides automated, user-specific feedback by comparing trainee performance to expert benchmarks and highlighting deviations from optimal execution through understandable proxies for actionable guidance. In a prospective user study with medical students, we compare the impact of XAI-guided feedback against traditional video-based coaching on task outcomes, cognitive load, and trainees' perceptions of AI-assisted learning. Results showed improved cognitive load and confidence post-intervention. While no differences emerged between the two feedback types in reducing performance gaps or practice adjustments, trends in the XAI group revealed desirable effects where participants more closely mimicked expert practice. This work encourages the study of explainable AI in surgical education and the development of data-driven, adaptive feedback mechanisms that could transform learning experiences and competency assessment.

Haomin Chen, T. Y. Alvin Liu, Catalina Gomez et al.

Algorithmic decision support is rapidly becoming a staple of personalized medicine, especially for high-stakes recommendations in which access to certain information can drastically alter the course of treatment, and thus, patient outcome; a prominent example is radiomics for cancer subtyping. Because in these scenarios the stakes are high, it is desirable for decision systems to not only provide recommendations but supply transparent reasoning in support thereof. For learning-based systems, this can be achieved through an interpretable design of the inference pipeline. Herein we describe an automated yet interpretable system for uveal melanoma subtyping with digital cytology images from fine needle aspiration biopsies. Our method embeds every automatically segmented cell of a candidate cytology image as a point in a 2D manifold defined by many representative slides, which enables reasoning about the cell-level composition of the tissue sample, paving the way for interpretable subtyping of the biopsy. Finally, a rule-based slide-level classification algorithm is trained on the partitions of the circularly distorted 2D manifold. This process results in a simple rule set that is evaluated automatically but highly transparent for human verification. On our in house cytology dataset of 88 uveal melanoma patients, the proposed method achieves an accuracy of 87.5% that compares favorably to all competing approaches, including deep "black box" models. The method comes with a user interface to facilitate interaction with cell-level content, which may offer additional insights for pathological assessment.

Mauricio Neira, Catalina Gómez, John F. Suárez-Pérez et al.

We introduce MANTRA, an annotated dataset of 4869 transient and 71207 non-transient object lightcurves built from the Catalina Real Time Transient Survey. We provide public access to this dataset as a plain text file to facilitate standardized quantitative comparison of astronomical transient event recognition algorithms. Some of the classes included in the dataset are: supernovae, cataclysmic variables, active galactic nuclei, high proper motion stars, blazars and flares. As an example of the tasks that can be performed on the dataset we experiment with multiple data pre-processing methods, feature selection techniques and popular machine learning algorithms (Support Vector Machines, Random Forests and Neural Networks). We assess quantitative performance in two classification tasks: binary (transient/non-transient) and eight-class classification. The best performing algorithm in both tasks is the Random Forest Classifier. It achieves an F1-score of 96.25% in the binary classification and 52.79% in the eight-class classification. For the eight-class classification, non-transients ( 96.83% ) is the class with the highest F1-score, while the lowest corresponds to high-proper-motion stars ( 16.79% ); for supernovae it achieves a value of 54.57% , close to the average across classes. The next release of MANTRA includes images and benchmarks with deep learning models.

Catalina Gómez, Mauricio Neira, Marcela Hernández Hoyos et al.

Supervised classification of temporal sequences of astronomical images into meaningful transient astrophysical phenomena has been considered a hard problem because it requires the intervention of human experts. The classifier uses the expert's knowledge to find heuristic features to process the images, for instance, by performing image subtraction or by extracting sparse information such as flux time series, also known as light curves. We present a successful deep learning approach that learns directly from imaging data. Our method models explicitly the spatio-temporal patterns with Deep Convolutional Neural Networks and Gated Recurrent Units. We train these deep neural networks using 1.3 million real astronomical images from the Catalina Real-Time Transient Survey to classify the sequences into five different types of astronomical transient classes. The TAO-Net (for Transient Astronomical Objects Network) architecture outperforms the results from random forest classification on light curves by 10 percentage points as measured by the F1 score for each class; the average F1 over classes goes from $45\%$ with random forest classification to $55\%$ with TAO-Net. This achievement with TAO-Net opens the possibility to develop new deep learning architectures for early transient detection. We make available the training dataset and trained models of TAO-Net to allow for future extensions of this work.