Wenhao Tang

Wenhao Tang, Fengtao Zhou, Sheng Huang et al.

Multiple instance learning (MIL) is the most widely used framework in computational pathology, encompassing sub-typing, diagnosis, prognosis, and more. However, the existing MIL paradigm typically requires an offline instance feature extractor, such as a pre-trained ResNet or a foundation model. This approach lacks the capability for feature fine-tuning within the specific downstream tasks, limiting its adaptability and performance. To address this issue, we propose a Re-embedded Regional Transformer (R$^2$T) for re-embedding the instance features online, which captures fine-grained local features and establishes connections across different regions. Unlike existing works that focus on pre-training powerful feature extractor or designing sophisticated instance aggregator, R$^2$T is tailored to re-embed instance features online. It serves as a portable module that can seamlessly integrate into mainstream MIL models. Extensive experimental results on common computational pathology tasks validate that: 1) feature re-embedding improves the performance of MIL models based on ResNet-50 features to the level of foundation model features, and further enhances the performance of foundation model features; 2) the R$^2$T can introduce more significant performance improvements to various MIL models; 3) R$^2$T-MIL, as an R$^2$T-enhanced AB-MIL, outperforms other latest methods by a large margin.The code is available at: https://github.com/DearCaat/RRT-MIL.

Yuxuan Li, Yicheng Zhang, Wenhao Tang et al.

Modern computer vision is converging on a closed loop in which perception, reasoning and generation mutually reinforce each other. However, this loop remains incomplete: the top-down influence of high-level reasoning on the foundational learning of low-level perceptual features is not yet underexplored. This paper addresses this gap by proposing a new paradigm for pretraining foundation models in downstream domains. We introduce Visual insTruction Pretraining (ViTP), a novel approach that directly leverages reasoning to enhance perception. ViTP embeds a Vision Transformer (ViT) backbone within a Vision-Language Model and pretrains it end-to-end using a rich corpus of visual instruction data curated from target downstream domains. ViTP is powered by our proposed Visual Robustness Learning (VRL), which compels the ViT to learn robust and domain-relevant features from a sparse set of visual tokens. Extensive experiments on 16 challenging remote sensing and medical imaging benchmarks demonstrate that ViTP establishes new state-of-the-art performance across a diverse range of downstream tasks. The code is available at https://github.com/zcablii/ViTP.

Tao He, Sheng Huang, Wenhao Tang et al.

Scene text detection is a challenging computer vision task due to the high variation in text shapes and ratios. In this work, we propose a scene text detector named Deformable Kernel Expansion (DKE), which incorporates the merits of both segmentation and contour-based detectors. DKE employs a segmentation module to segment the shrunken text region as the text kernel, then expands the text kernel contour to obtain text boundary by regressing the vertex-wise offsets. Generating the text kernel by segmentation enables DKE to inherit the arbitrary-shaped text region modeling capability of segmentation-based detectors. Regressing the kernel contour with some sampled vertices enables DKE to avoid the complicated pixel-level post-processing and better learn contour deformation as the contour-based detectors. Moreover, we propose an Optimal Bipartite Graph Matching Loss (OBGML) that measures the matching error between the predicted contour and the ground truth, which efficiently minimizes the global contour matching distance. Extensive experiments on CTW1500, Total-Text, MSRA-TD500, and ICDAR2015 demonstrate that DKE achieves a good tradeoff between accuracy and efficiency in scene text detection.

Ming Hu, Chenglong Ma, Wei Li et al. · pku

Scientific Large Language Models (Sci-LLMs) are transforming how knowledge is represented, integrated, and applied in scientific research, yet their progress is shaped by the complex nature of scientific data. This survey presents a comprehensive, data-centric synthesis that reframes the development of Sci-LLMs as a co-evolution between models and their underlying data substrate. We formulate a unified taxonomy of scientific data and a hierarchical model of scientific knowledge, emphasizing the multimodal, cross-scale, and domain-specific challenges that differentiate scientific corpora from general natural language processing datasets. We systematically review recent Sci-LLMs, from general-purpose foundations to specialized models across diverse scientific disciplines, alongside an extensive analysis of over 270 pre-/post-training datasets, showing why Sci-LLMs pose distinct demands -- heterogeneous, multi-scale, uncertainty-laden corpora that require representations preserving domain invariance and enabling cross-modal reasoning. On evaluation, we examine over 190 benchmark datasets and trace a shift from static exams toward process- and discovery-oriented assessments with advanced evaluation protocols. These data-centric analyses highlight persistent issues in scientific data development and discuss emerging solutions involving semi-automated annotation pipelines and expert validation. Finally, we outline a paradigm shift toward closed-loop systems where autonomous agents based on Sci-LLMs actively experiment, validate, and contribute to a living, evolving knowledge base. Collectively, this work provides a roadmap for building trustworthy, continually evolving artificial intelligence (AI) systems that function as a true partner in accelerating scientific discovery.