Muhammad Imran Malik

Moises Diaz, Miguel A. Ferrer, Donato Impedovo et al.

Handwritten signatures are biometric traits at the center of debate in the scientific community. Over the last 40 years, the interest in signature studies has grown steadily, having as its main reference the application of automatic signature verification, as previously published reviews in 1989, 2000, and 2008 bear witness. Ever since, and over the last 10 years, the application of handwritten signature technology has strongly evolved, and much research has focused on the possibility of applying systems based on handwritten signature analysis and processing to a multitude of new fields. After several years of haphazard growth of this research area, it is time to assess its current developments for their applicability in order to draw a structured way forward. This perspective reports a systematic review of the last 10 years of the literature on handwritten signatures with respect to the new scenario, focusing on the most promising domains of research and trying to elicit possible future research directions in this subject.

Sheraz Ahmed, Muhammad Imran Malik, Muhammad Zeshan Afzal et al.

The contribution of this paper is fourfold. The first contribution is a novel, generic method for automatic ground truth generation of camera-captured document images (books, magazines, articles, invoices, etc.). It enables us to build large-scale (i.e., millions of images) labeled camera-captured/scanned documents datasets, without any human intervention. The method is generic, language independent and can be used for generation of labeled documents datasets (both scanned and cameracaptured) in any cursive and non-cursive language, e.g., English, Russian, Arabic, Urdu, etc. To assess the effectiveness of the presented method, two different datasets in English and Russian are generated using the presented method. Evaluation of samples from the two datasets shows that 99:98% of the images were correctly labeled. The second contribution is a large dataset (called C3Wi) of camera-captured characters and words images, comprising 1 million word images (10 million character images), captured in a real camera-based acquisition. This dataset can be used for training as well as testing of character recognition systems on camera-captured documents. The third contribution is a novel method for the recognition of cameracaptured document images. The proposed method is based on Long Short-Term Memory and outperforms the state-of-the-art methods for camera based OCRs. As a fourth contribution, various benchmark tests are performed to uncover the behavior of commercial (ABBYY), open source (Tesseract), and the presented camera-based OCR using the presented C3Wi dataset. Evaluation results reveal that the existing OCRs, which already get very high accuracies on scanned documents, have limited performance on camera-captured document images; where ABBYY has an accuracy of 75%, Tesseract an accuracy of 50.22%, while the presented character recognition system has an accuracy of 95.10%.

Adriano Lucieri, Muhammad Naseer Bajwa, Stephan Alexander Braun et al.

One principal impediment in the successful deployment of AI-based Computer-Aided Diagnosis (CAD) systems in clinical workflows is their lack of transparent decision making. Although commonly used eXplainable AI methods provide some insight into opaque algorithms, such explanations are usually convoluted and not readily comprehensible except by highly trained experts. The explanation of decisions regarding the malignancy of skin lesions from dermoscopic images demands particular clarity, as the underlying medical problem definition is itself ambiguous. This work presents ExAID (Explainable AI for Dermatology), a novel framework for biomedical image analysis, providing multi-modal concept-based explanations consisting of easy-to-understand textual explanations supplemented by visual maps justifying the predictions. ExAID relies on Concept Activation Vectors to map human concepts to those learnt by arbitrary Deep Learning models in latent space, and Concept Localization Maps to highlight concepts in the input space. This identification of relevant concepts is then used to construct fine-grained textual explanations supplemented by concept-wise location information to provide comprehensive and coherent multi-modal explanations. All information is comprehensively presented in a diagnostic interface for use in clinical routines. An educational mode provides dataset-level explanation statistics and tools for data and model exploration to aid medical research and education. Through rigorous quantitative and qualitative evaluation of ExAID, we show the utility of multi-modal explanations for CAD-assisted scenarios even in case of wrong predictions. We believe that ExAID will provide dermatologists an effective screening tool that they both understand and trust. Moreover, it will be the basis for similar applications in other biomedical imaging fields.

Adriano Lucieri, Muhammad Naseer Bajwa, Stephan Alexander Braun et al.

Deep learning based medical image classifiers have shown remarkable prowess in various application areas like ophthalmology, dermatology, pathology, and radiology. However, the acceptance of these Computer-Aided Diagnosis (CAD) systems in real clinical setups is severely limited primarily because their decision-making process remains largely obscure. This work aims at elucidating a deep learning based medical image classifier by verifying that the model learns and utilizes similar disease-related concepts as described and employed by dermatologists. We used a well-trained and high performing neural network developed by REasoning for COmplex Data (RECOD) Lab for classification of three skin tumours, i.e. Melanocytic Naevi, Melanoma and Seborrheic Keratosis and performed a detailed analysis on its latent space. Two well established and publicly available skin disease datasets, PH2 and derm7pt, are used for experimentation. Human understandable concepts are mapped to RECOD image classification model with the help of Concept Activation Vectors (CAVs), introducing a novel training and significance testing paradigm for CAVs. Our results on an independent evaluation set clearly shows that the classifier learns and encodes human understandable concepts in its latent representation. Additionally, TCAV scores (Testing with CAVs) suggest that the neural network indeed makes use of disease-related concepts in the correct way when making predictions. We anticipate that this work can not only increase confidence of medical practitioners on CAD but also serve as a stepping stone for further development of CAV-based neural network interpretation methods.

Muhammad Nabeel Asima, Muhammad Imran Malik, Andreas Dengela et al.

Functional or non-coding RNAs are attracting more attention as they are now potentially considered valuable resources in the development of new drugs intended to cure several human diseases. The identification of drugs targeting the regulatory circuits of functional RNAs depends on knowing its family, a task which is known as RNA sequence classification. State-of-the-art small noncoding RNA classification methodologies take secondary structural features as input. However, in such classification, feature extraction approaches only take global characteristics into account and completely oversight co-relative effect of local structures. Furthermore secondary structure based approaches incorporate high dimensional feature space which proves computationally expensive. This paper proposes a novel Robust and Precise ConvNet (RPC-snRC) methodology which classifies small non-coding RNAs sequences into their relevant families by utilizing the primary sequence of RNAs. RPC-snRC methodology learns hierarchical representation of features by utilizing positioning and occurrences information of nucleotides. To avoid exploding and vanishing gradient problems, we use an approach similar to DenseNet in which gradient can flow straight from subsequent layers to previous layers. In order to assess the effectiveness of deeper architectures for small non-coding RNA classification, we also adapted two ResNet architectures having different number of layers. Experimental results on a benchmark small non-coding RNA dataset show that our proposed methodology does not only outperform existing small non-coding RNA classification approaches with a significant performance margin of 10% but it also outshines adapted ResNet architectures.

Muhammad Nabeel Asim, Muhammad Usman Ghani Khan, Muhammad Imran Malik et al.

Text document classification is an important task for diverse natural language processing based applications. Traditional machine learning approaches mainly focused on reducing dimensionality of textual data to perform classification. This although improved the overall classification accuracy, the classifiers still faced sparsity problem due to lack of better data representation techniques. Deep learning based text document classification, on the other hand, benefitted greatly from the invention of word embeddings that have solved the sparsity problem and researchers focus mainly remained on the development of deep architectures. Deeper architectures, however, learn some redundant features that limit the performance of deep learning based solutions. In this paper, we propose a two stage text document classification methodology which combines traditional feature engineering with automatic feature engineering (using deep learning). The proposed methodology comprises a filter based feature selection (FSE) algorithm followed by a deep convolutional neural network. This methodology is evaluated on the two most commonly used public datasets, i.e., 20 Newsgroups data and BBC news data. Evaluation results reveal that the proposed methodology outperforms the state-of-the-art of both the (traditional) machine learning and deep learning based text document classification methodologies with a significant margin of 7.7% on 20 Newsgroups and 6.6% on BBC news datasets.

Muhammad Ali Chattha, Shoaib Ahmed Siddiqui, Muhammad Imran Malik et al.

The promise of ANNs to automatically discover and extract useful features/patterns from data without dwelling on domain expertise although seems highly promising but comes at the cost of high reliance on large amount of accurately labeled data, which is often hard to acquire and formulate especially in time-series domains like anomaly detection, natural disaster management, predictive maintenance and healthcare. As these networks completely rely on data and ignore a very important modality i.e. expert, they are unable to harvest any benefit from the expert knowledge, which in many cases is very useful. In this paper, we try to bridge the gap between these data driven and expert knowledge based systems by introducing a novel framework for incorporating expert knowledge into the network (KINN). Integrating expert knowledge into the network has three key advantages: (a) Reduction in the amount of data needed to train the model, (b) provision of a lower bound on the performance of the resulting classifier by obtaining the best of both worlds, and (c) improved convergence of model parameters (model converges in smaller number of epochs). Although experts are extremely good in solving different tasks, there are some trends and patterns, which are usually hidden only in the data. Therefore, KINN employs a novel residual knowledge incorporation scheme, which can automatically determine the quality of the predictions made by the expert and rectify it accordingly by learning the trends/patterns from data. Specifically, the method tries to use information contained in one modality to complement information missed by the other. We evaluated KINN on a real world traffic flow prediction problem. KINN significantly superseded performance of both the expert and as well as the base network (LSTM in this case) when evaluated in isolation, highlighting its superiority for the task.

Ayushman Dash, Amit Sahu, Rajveer Shringi et al.

This paper presents a novel approach, called AirScript, for creating, recognizing and visualizing documents in air. We present a novel algorithm, called 2-DifViz, that converts the hand movements in air (captured by a Myo-armband worn by a user) into a sequence of x, y coordinates on a 2D Cartesian plane, and visualizes them on a canvas. Existing sensor-based approaches either do not provide visual feedback or represent the recognized characters using prefixed templates. In contrast, AirScript stands out by giving freedom of movement to the user, as well as by providing a real-time visual feedback of the written characters, making the interaction natural. AirScript provides a recognition module to predict the content of the document created in air. To do so, we present a novel approach based on deep learning, which uses the sensor data and the visualizations created by 2-DifViz. The recognition module consists of a Convolutional Neural Network (CNN) and two Gated Recurrent Unit (GRU) Networks. The output from these three networks is fused to get the final prediction about the characters written in air. AirScript can be used in highly sophisticated environments like a smart classroom, a smart factory or a smart laboratory, where it would enable people to annotate pieces of texts wherever they want without any reference surface. We have evaluated AirScript against various well-known learning models (HMM, KNN, SVM, etc.) on the data of 12 participants. Evaluation results show that the recognition module of AirScript largely outperforms all of these models by achieving an accuracy of 91.7% in a person independent evaluation and a 96.7% accuracy in a person dependent evaluation.