An Extensive Data Processing Pipeline for MIMIC-IVMehak Gupta, Brennan Gallamoza, Nicolas Cutrona et al.
An increasing amount of research is being devoted to applying machine learning methods to electronic health record (EHR) data for various clinical purposes. This growing area of research has exposed the challenges of the accessibility of EHRs. MIMIC is a popular, public, and free EHR dataset in a raw format that has been used in numerous studies. The absence of standardized pre-processing steps can be, however, a significant barrier to the wider adoption of this rare resource. Additionally, this absence can reduce the reproducibility of the developed tools and limit the ability to compare the results among similar studies. In this work, we provide a greatly customizable pipeline to extract, clean, and pre-process the data available in the fourth version of the MIMIC dataset (MIMIC-IV). The pipeline also presents an end-to-end wizard-like package supporting predictive model creations and evaluations. The pipeline covers a range of clinical prediction tasks which can be broadly classified into four categories - readmission, length of stay, mortality, and phenotype prediction. The tool is publicly available at https://github.com/healthylaife/MIMIC-IV-Data-Pipeline.
An Interoperable Machine Learning Pipeline for Pediatric Obesity Risk EstimationHamed Fayyaz, Mehak Gupta, Alejandra Perez Ramirez et al.
Reliable prediction of pediatric obesity can offer a valuable resource to providers, helping them engage in timely preventive interventions before the disease is established. Many efforts have been made to develop ML-based predictive models of obesity, and some studies have reported high predictive performances. However, no commonly used clinical decision support tool based on existing ML models currently exists. This study presents a novel end-to-end pipeline specifically designed for pediatric obesity prediction, which supports the entire process of data extraction, inference, and communication via an API or a user interface. While focusing only on routinely recorded data in pediatric electronic health records (EHRs), our pipeline uses a diverse expert-curated list of medical concepts to predict the 1-3 years risk of developing obesity. Furthermore, by using the Fast Healthcare Interoperability Resources (FHIR) standard in our design procedure, we specifically target facilitating low-effort integration of our pipeline with different EHR systems. In our experiments, we report the effectiveness of the predictive model as well as its alignment with the feedback from various stakeholders, including ML scientists, providers, health IT personnel, health administration representatives, and patient group representatives.
5.8CVOct 25, 2020
Generalized Iris Presentation Attack Detection Algorithm under Cross-Database SettingsMehak Gupta, Vishal Singh, Akshay Agarwal et al.
Presentation attacks are posing major challenges to most of the biometric modalities. Iris recognition, which is considered as one of the most accurate biometric modality for person identification, has also been shown to be vulnerable to advanced presentation attacks such as 3D contact lenses and textured lens. While in the literature, several presentation attack detection (PAD) algorithms are presented; a significant limitation is the generalizability against an unseen database, unseen sensor, and different imaging environment. To address this challenge, we propose a generalized deep learning-based PAD network, MVANet, which utilizes multiple representation layers. It is inspired by the simplicity and success of hybrid algorithm or fusion of multiple detection networks. The computational complexity is an essential factor in training deep neural networks; therefore, to reduce the computational complexity while learning multiple feature representation layers, a fixed base model has been used. The performance of the proposed network is demonstrated on multiple databases such as IIITD-WVU MUIPA and IIITD-CLI databases under cross-database training-testing settings, to assess the generalizability of the proposed algorithm.