Xiangru Tang

Anni Zou, Zhuosheng Zhang, Hai Zhao et al.

Large language models (LLMs) have unveiled remarkable reasoning capabilities by exploiting chain-of-thought (CoT) prompting, which generates intermediate reasoning chains to serve as the rationale for deriving the answer. However, current CoT methods either simply employ general prompts such as Let's think step by step, or heavily rely on pre-defined task-specific demonstrations to attain preferable performances, thereby engendering an inescapable gap between performance and generalization. To bridge this gap, we propose GeM-CoT, a Generalizable CoT prompting mechanism in Mixed-task scenarios where the type of input questions is unknown. GeM-CoT first categorizes the question type and subsequently samples or constructs demonstrations from the corresponding data pool in an automatic pattern. With this technical design, GeM-CoT simultaneously enjoys superior generalization capabilities and remarkable performances on 10 public reasoning tasks and 23 BBH tasks.

Yin Fang, Kangwei Liu, Ningyu Zhang et al.

As Large Language Models (LLMs) rapidly evolve, their influence in science is becoming increasingly prominent. The emerging capabilities of LLMs in task generalization and free-form dialogue can significantly advance fields like chemistry and biology. However, the field of single-cell biology, which forms the foundational building blocks of living organisms, still faces several challenges. High knowledge barriers and limited scalability in current methods restrict the full exploitation of LLMs in mastering single-cell data, impeding direct accessibility and rapid iteration. To this end, we introduce ChatCell, which signifies a paradigm shift by facilitating single-cell analysis with natural language. Leveraging vocabulary adaptation and unified sequence generation, ChatCell has acquired profound expertise in single-cell biology and the capability to accommodate a diverse range of analysis tasks. Extensive experiments further demonstrate ChatCell's robust performance and potential to deepen single-cell insights, paving the way for more accessible and intuitive exploration in this pivotal field. Our project homepage is available at https://zjunlp.github.io/project/ChatCell.

Siru Ouyang, Jun Yan, I-Hung Hsu et al.

With the growing adoption of large language model agents in persistent real-world roles, they naturally encounter continuous streams of tasks. A key limitation, however, is their failure to learn from the accumulated interaction history, forcing them to discard valuable insights and repeat past errors. We propose ReasoningBank, a novel memory framework that distills generalizable reasoning strategies from an agent's self-judged successful and failed experiences. At test time, an agent retrieves relevant memories from ReasoningBank to inform its interaction and then integrates new learnings back, enabling it to become more capable over time. Building on this powerful experience learner, we further introduce memory-aware test-time scaling (MaTTS), which accelerates and diversifies this learning process by scaling up the agent's interaction experience. By allocating more compute to each task, the agent generates abundant, diverse experiences that provide rich contrastive signals for synthesizing higher-quality memory. The better memory in turn guides more effective scaling, establishing a powerful synergy between memory and test-time scaling. Across web browsing and software engineering benchmarks, ReasoningBank consistently outperforms existing memory mechanisms that store raw trajectories or only successful task routines, improving both effectiveness and efficiency; MaTTS further amplifies these gains. These findings establish memory-driven experience scaling as a new scaling dimension, enabling agents to self-evolve with emergent behaviors naturally arise.

Guancheng Wan, Lucheng Fu, Haoxin Liu et al.

The performance of Large Language Models (LLMs) hinges on carefully engineered prompts. However, prevailing prompt optimization methods, ranging from heuristic edits and reinforcement learning to evolutionary search, primarily target point-wise accuracy. They seldom enforce paraphrase invariance or searching stability, and therefore cannot remedy this brittleness in practice. Automated prompt search remains brittle: small, semantically preserving paraphrases often cause large performance swings. We identify this brittleness as the textual sharpness of the prompt landscape. In this work, we provide the first formal treatment of textual sharpness in the discrete, semantic space of prompts, together with an operational robustness criterion over a semantic neighborhood; the design is black-box or API-only, requiring no gradients to update the model's parameters. Then we introduce TARE (Textual Sharpness-Aware Evolving), a derivative-free framework that alternates between an inner, sampling-based adversarial search that stresses a prompt with hard paraphrases and an outer, robust selection that prefers candidates whose neighborhoods remain strong. We further propose ATARE, which learns anisotropic weights to shape the semantic neighborhood and adapts its radius over time to balance exploration and fidelity. Diverse tasks evaluate our methods, whose design for minimizing textual sharpness gap leads to prompts that preserve accuracy under paraphrasing, outperforming accuracy-only prompt search while remaining computationally practical.

Shentong Mo, Xi Fu, Chenyang Hong et al.

In the genome biology research, regulatory genome modeling is an important topic for many regulatory downstream tasks, such as promoter classification, transaction factor binding sites prediction. The core problem is to model how regulatory elements interact with each other and its variability across different cell types. However, current deep learning methods often focus on modeling genome sequences of a fixed set of cell types and do not account for the interaction between multiple regulatory elements, making them only perform well on the cell types in the training set and lack the generalizability required in biological applications. In this work, we propose a simple yet effective approach for pre-training genome data in a multi-modal and self-supervised manner, which we call GeneBERT. Specifically, we simultaneously take the 1d sequence of genome data and a 2d matrix of (transcription factors x regions) as the input, where three pre-training tasks are proposed to improve the robustness and generalizability of our model. We pre-train our model on the ATAC-seq dataset with 17 million genome sequences. We evaluate our GeneBERT on regulatory downstream tasks across different cell types, including promoter classification, transaction factor binding sites prediction, disease risk estimation, and splicing sites prediction. Extensive experiments demonstrate the effectiveness of multi-modal and self-supervised pre-training for large-scale regulatory genomics data.

Xiangru Tang, Alexander Fabbri, Haoran Li et al.

Current pre-trained models applied to summarization are prone to factual inconsistencies which either misrepresent the source text or introduce extraneous information. Thus, comparing the factual consistency of summaries is necessary as we develop improved models. However, the optimal human evaluation setup for factual consistency has not been standardized. To address this issue, we crowdsourced evaluations for factual consistency using the rating-based Likert scale and ranking-based Best-Worst Scaling protocols, on 100 articles from each of the CNN-Daily Mail and XSum datasets over four state-of-the-art models, to determine the most reliable evaluation framework. We find that ranking-based protocols offer a more reliable measure of summary quality across datasets, while the reliability of Likert ratings depends on the target dataset and the evaluation design. Our crowdsourcing templates and summary evaluations will be publicly available to facilitate future research on factual consistency in summarization.

Linyong Nan, Chiachun Hsieh, Ziming Mao et al.

Existing table question answering datasets contain abundant factual questions that primarily evaluate the query and schema comprehension capability of a system, but they fail to include questions that require complex reasoning and integration of information due to the constraint of the associated short-form answers. To address these issues and to demonstrate the full challenge of table question answering, we introduce FeTaQA, a new dataset with 10K Wikipedia-based {table, question, free-form answer, supporting table cells} pairs. FeTaQA yields a more challenging table question answering setting because it requires generating free-form text answers after retrieval, inference, and integration of multiple discontinuous facts from a structured knowledge source. Unlike datasets of generative QA over text in which answers are prevalent with copies of short text spans from the source, answers in our dataset are human-generated explanations involving entities and their high-level relations. We provide two benchmark methods for the proposed task: a pipeline method based on semantic-parsing-based QA systems and an end-to-end method based on large pretrained text generation models, and show that FeTaQA poses a challenge for both methods.

Xiangru Tang, Alan Aw

Detection of semantic similarity plays a vital role in sentence matching. It requires to learn discriminative representations of natural language. Recently, owing to more and more sophisticated model architecture, impressive progress has been made, along with a time-consuming training process and not-interpretable inference. To alleviate this problem, we explore a metric learning approach, named FILM (Fast, Interpretable, and Low-rank Metric learning) to efficiently find a high discriminative projection of the high-dimensional data. We construct this metric learning problem as a manifold optimization problem and solve it with the Cayley transformation method with the Barzilai-Borwein step size. In experiments, we apply FILM with triplet loss minimization objective to the Quora Challenge and Semantic Textual Similarity (STS) Task. The results demonstrate that the FILM method achieves superior performance as well as the fastest computation speed, which is consistent with our theoretical analysis of time complexity.

Xiangru Tang, Haoyuan Wang, Xiang Pan et al.

Abstract visual reasoning connects mental abilities to the physical world, which is a crucial factor in cognitive development. Most toddlers display sensitivity to this skill, but it is not easy for machines. Aimed at it, we focus on the Raven Progressive Matrices Test, designed to measure cognitive reasoning. Recent work designed some black-boxes to solve it in an end-to-end fashion, but they are incredibly complicated and difficult to explain. Inspired by cognitive studies, we propose a Multi-Granularity Modularized Network (MMoN) to bridge the gap between the processing of raw sensory information and symbolic reasoning. Specifically, it learns modularized reasoning functions to model the semantic rule from the visual grounding in a neuro-symbolic and semi-supervision way. To comprehensively evaluate MMoN, our experiments are conducted on the dataset of both seen and unseen reasoning rules. The result shows that MMoN is well suited for abstract visual reasoning and also explainable on the generalization test.

Hongru Wang, Xiangru Tang, Sunny Lai et al.

This paper describes our system submitted to task 4 of SemEval 2020: Commonsense Validation and Explanation (ComVE) which consists of three sub-tasks. The task is to directly validate the given sentence whether or not it makes sense and require the model to explain it. Based on BERTarchitecture with a multi-task setting, we propose an effective and interpretable "Explain, Reason and Predict" (ERP) system to solve the three sub-tasks about commonsense: (a) Validation, (b)Reasoning, and (c) Explanation. Inspired by cognitive studies of common sense, our system first generates a reason or understanding of the sentences and then chooses which one statement makes sense, which is achieved by multi-task learning. During the post-evaluation, our system has reached 92.9% accuracy in subtask A (rank 11), 89.7% accuracy in subtask B (rank 9), andBLEU score of 12.9 in subtask C (rank 8)