Ekram Hossain

Md Saiful Islam, Ekram Hossain, Abdelrahman Abdelkader et al.

Video-based assessments offer a scalable pathway for remote Parkinson's disease (PD) screening. While traditional approaches rely on handcrafted features mimicking clinical scales, recent advances in video foundation models (VFMs) enable representation learning without task-specific customization. However, the comparative effectiveness of different VFM architectures across diverse clinical tasks remains poorly understood. We present a large-scale systematic study using a novel video dataset from 1,888 participants (727 with PD), comprising 32,847 videos across 16 standardized clinical tasks. We evaluate seven state-of-the-art VFMs -- including VideoPrism, V-JEPA, ViViT, and VideoMAE -- to determine their robustness in clinical screening. By evaluating frozen embeddings with a linear classification head, we demonstrate that task saliency is highly model-dependent: VideoPrism excels in capturing visual speech kinematics (no audio) and facial expressivity, while V-JEPA proves superior for upper-limb motor tasks. Notably, TimeSformer remains highly competitive for rhythmic tasks like finger tapping. Our experiments yield AUCs of 76.4 - 85.3% and accuracies of 71.5 - 80.6%. While high specificity (up to 90.3%) suggests strong potential for ruling out healthy individuals, the lower sensitivity (43.2 - 57.3%) highlights the need for task-aware calibration and integration of multiple tasks and modalities. Overall, this work establishes a rigorous baseline for VFM-based PD screening and provides a roadmap for selecting suitable tasks and architectures in remote neurological monitoring. Code and anonymized structured data are publicly available: https://anonymous.4open.science/r/parkinson\_video\_benchmarking-A2C5

Tariq Adnan, Abdelrahman Abdelkader, Zipei Liu et al.

We present a framework to recognize Parkinson's disease (PD) through an English pangram utterance speech collected using a web application from diverse recording settings and environments, including participants' homes. Our dataset includes a global cohort of 1306 participants, including 392 diagnosed with PD. Leveraging the diversity of the dataset, spanning various demographic properties (such as age, sex, and ethnicity), we used deep learning embeddings derived from semi-supervised models such as Wav2Vec 2.0, WavLM, and ImageBind representing the speech dynamics associated with PD. Our novel fusion model for PD classification, which aligns different speech embeddings into a cohesive feature space, demonstrated superior performance over standard concatenation-based fusion models and other baselines (including models built on traditional acoustic features). In a randomized data split configuration, the model achieved an Area Under the Receiver Operating Characteristic Curve (AUROC) of 88.94% and an accuracy of 85.65%. Rigorous statistical analysis confirmed that our model performs equitably across various demographic subgroups in terms of sex, ethnicity, and age, and remains robust regardless of disease duration. Furthermore, our model, when tested on two entirely unseen test datasets collected from clinical settings and from a PD care center, maintained AUROC scores of 82.12% and 78.44%, respectively. This affirms the model's robustness and it's potential to enhance accessibility and health equity in real-world applications.