Shoujun Zhou

Fuchen Zheng, Xinyi Chen, Xuhang Chen et al.

Medical image segmentation, a crucial task in computer vision, facilitates the automated delineation of anatomical structures and pathologies, supporting clinicians in diagnosis, treatment planning, and disease monitoring. Notably, transformers employing shifted window-based self-attention have demonstrated exceptional performance. However, their reliance on local window attention limits the fusion of local and global contextual information, crucial for segmenting microtumors and miniature organs. To address this limitation, we propose the Adaptive Semantic Segmentation Network (ASSNet), a transformer architecture that effectively integrates local and global features for precise medical image segmentation. ASSNet comprises a transformer-based U-shaped encoder-decoder network. The encoder utilizes shifted window self-attention across five resolutions to extract multi-scale features, which are then propagated to the decoder through skip connections. We introduce an augmented multi-layer perceptron within the encoder to explicitly model long-range dependencies during feature extraction. Recognizing the constraints of conventional symmetrical encoder-decoder designs, we propose an Adaptive Feature Fusion (AFF) decoder to complement our encoder. This decoder incorporates three key components: the Long Range Dependencies (LRD) block, the Multi-Scale Feature Fusion (MFF) block, and the Adaptive Semantic Center (ASC) block. These components synergistically facilitate the effective fusion of multi-scale features extracted by the decoder while capturing long-range dependencies and refining object boundaries. Comprehensive experiments on diverse medical image segmentation tasks, including multi-organ, liver tumor, and bladder tumor segmentation, demonstrate that ASSNet achieves state-of-the-art results. Code and models are available at: \url{https://github.com/lzeeorno/ASSNet}.

Zhenxi Zhang, Fuchen Zheng, Adnan Iltaf et al.

Accurate segmentation of aortic vascular structures is critical for diagnosing and treating cardiovascular diseases.Traditional Transformer-based models have shown promise in this domain by capturing long-range dependencies between vascular features. However, their reliance on fixed-size rectangular patches often influences the integrity of complex vascular structures, leading to suboptimal segmentation accuracy. To address this challenge, we propose the adaptive Morph Patch Transformer (MPT), a novel architecture specifically designed for aortic vascular segmentation. Specifically, MPT introduces an adaptive patch partitioning strategy that dynamically generates morphology-aware patches aligned with complex vascular structures. This strategy can preserve semantic integrity of complex vascular structures within individual patches. Moreover, a Semantic Clustering Attention (SCA) method is proposed to dynamically aggregate features from various patches with similar semantic characteristics. This method enhances the model's capability to segment vessels of varying sizes, preserving the integrity of vascular structures. Extensive experiments on three open-source dataset(AVT, AortaSeg24 and TBAD) demonstrate that MPT achieves state-of-the-art performance, with improvements in segmenting intricate vascular structures.

Yifan Xiang, Zhenxi Zhang, Bin Li et al.

Recent advances in personalized MLLMs enable effective capture of user-specific concepts, supporting both recognition of personalized concepts and contextual captioning. However, humans typically explore and reason over relations among objects and individuals, transcending surface-level information to achieve more personalized and contextual understanding. To this end, existing methods may face three main limitations: Their training data lacks multi-object sets in which relations among objects are learnable. Building on the limited training data, their models overlook the relations between different personalized concepts and fail to reason over them. Their experiments mainly focus on a single personalized concept, where evaluations are limited to recognition and captioning tasks. To address the limitations, we present a new dataset named ReGraP, consisting of 120 sets of personalized knowledge. Each set includes images, KGs, and CoT QA pairs derived from the KGs, enabling more structured and sophisticated reasoning pathways. We propose ReGraP-LLaVA, an MLLM trained with the corresponding KGs and CoT QA pairs, where soft and hard graph prompting methods are designed to align KGs within the model's semantic space. We establish the ReGraP Benchmark, which contains diverse task types: multiple-choice, fill-in-the-blank, True/False, and descriptive questions in both open- and closed-ended settings. The proposed benchmark is designed to evaluate the relational reasoning and knowledge-connection capability of personalized MLLMs. We conduct experiments on the proposed ReGraP-LLaVA and other competitive MLLMs. Results show that the proposed model not only learns personalized knowledge but also performs relational reasoning in responses, achieving the SoTA performance compared with the competitive methods. All the codes and datasets are released at: https://github.com/xyfyyds/ReGraP.

Chang Zong, Bin Li, Shoujun Zhou et al.

Locating specific segments within an instructional video is an efficient way to acquire guiding knowledge. Generally, the task of obtaining video segments for both verbal explanations and visual demonstrations is known as visual answer localization (VAL). However, users often need multiple interactions to obtain answers that align with their expectations when using the system. During these interactions, humans deepen their understanding of the video content by asking themselves questions, thereby accurately identifying the location. Therefore, we propose a new task, named In-VAL, to simulate the multiple interactions between humans and videos in the procedure of obtaining visual answers. The In-VAL task requires interactively addressing several semantic gap issues, including 1) the ambiguity of user intent in the input questions, 2) the incompleteness of language in video subtitles, and 3) the fragmentation of content in video segments. To address these issues, we propose Ask2Loc, a framework for resolving In-VAL by asking questions. It includes three key modules: 1) a chatting module to refine initial questions and uncover clear intentions, 2) a rewriting module to generate fluent language and create complete descriptions, and 3) a searching module to broaden local context and provide integrated content. We conduct extensive experiments on three reconstructed In-VAL datasets. Compared to traditional end-to-end and two-stage methods, our proposed Ask2Loc can improve performance by up to 14.91 (mIoU) on the In-VAL task. Our code and datasets can be accessed at https://github.com/changzong/Ask2Loc.

Adnan Iltaf, Rayan Merghani Ahmed, Zhenxi Zhang et al.

Medical image segmentation is crucial for clinical diagnosis and treatment planning, especially when dealing with complex anatomical structures such as vessels. However, accurately segmenting vessels remains challenging due to their small size, intricate edge structures, and susceptibility to artifacts and imaging noise. In this work, we propose VesselSAM, an enhanced version of the Segment Anything Model (SAM), specifically tailored for aortic vessel segmentation. VesselSAM incorporates AtrousLoRA, a novel module integrating Atrous Attention and Low-Rank Adaptation (LoRA), to enhance segmentation performance. Atrous Attention enables the model to capture multi-scale contextual information, preserving both fine-grained local details and broader global context. Additionally, LoRA facilitates efficient fine-tuning of the frozen SAM image encoder, reducing the number of trainable parameters and thereby enhancing computational efficiency. We evaluate VesselSAM using two challenging datasets: the Aortic Vessel Tree (AVT) dataset and the Type-B Aortic Dissection (TBAD) dataset. VesselSAM achieves state-of-the-art performance, attaining DSC scores of 93.50\%, 93.25\%, 93.02\%, and 93.26\% across multi-center datasets. Our results demonstrate that VesselSAM delivers high segmentation accuracy while significantly reducing computational overhead compared to existing large-scale models. This development paves the way for enhanced AI-based aortic vessel segmentation in clinical environments. The code and models will be released at https://github.com/Adnan-CAS/AtrousLora.

Rayan Merghani Ahmed, Adnan Iltaf, Mohamed Elmanna et al.

Accurate segmentation of coronary Digital Subtraction Angiography images is essential to diagnose and treat coronary artery diseases. Despite advances in deep learning, challenges such as high intra-class variance and class imbalance limit precise vessel delineation. Most existing approaches for coronary DSA segmentation cannot address these issues. Also, existing segmentation network's encoders do not directly generate semantic embeddings, which could enable the decoder to reconstruct segmentation masks effectively from these well-defined features. We propose a Supervised Prototypical Contrastive Loss that fuses supervised and prototypical contrastive learning to enhance coronary DSA image segmentation. The supervised contrastive loss enforces semantic embeddings in the encoder, improving feature differentiation. The prototypical contrastive loss allows the model to focus on the foreground class while alleviating the high intra-class variance and class imbalance problems by concentrating only on the hard-to-classify background samples. We implement the proposed SPCL loss within an MSA-UNet3+: a Multi-Scale Attention-Enhanced UNet3+ architecture. The architecture integrates key components: a Multi-Scale Attention Encoder and a Multi-Scale Dilated Bottleneck designed to enhance multi-scale feature extraction and a Contextual Attention Fusion Module built to keep fine-grained details while improving contextual understanding. Experiments on a private coronary DSA dataset show that MSA-UNet3+ outperforms state-of-the-art methods, achieving the highest Dice coefficient and F1-score and significantly reducing ASD and ACD. The developed framework provides clinicians with precise vessel segmentation, enabling accurate identification of coronary stenosis and supporting informed diagnostic and therapeutic decisions. The code will be released at https://github.com/rayanmerghani/MSA-UNet3plus.

Zhiqing Zhang, Tianyong Liu, Guojia Fan et al.

Accurate segmentation of 3D clinical medical images is critical in the diagnosis and treatment of spinal diseases. However, the inherent complexity of spinal anatomy and uncertainty inherent in current imaging technologies, poses significant challenges for semantic segmentation of spinal images. Although convolutional neural networks (CNNs) and Transformer-based models have made some progress in spinal segmentation, their limitations in handling long-range dependencies hinder further improvements in segmentation accuracy.To address these challenges, we introduce a residual visual Mamba layer to effectively capture and model the deep semantic features and long-range spatial dependencies of 3D spinal data. To further enhance the structural semantic understanding of the vertebrae, we also propose a novel spinal shape prior module that captures specific anatomical information of the spine from medical images, significantly enhancing the model's ability to extract structural semantic information of the vertebrae. Comparative and ablation experiments on two datasets demonstrate that SpineMamba outperforms existing state-of-the-art models. On the CT dataset, the average Dice similarity coefficient for segmentation reaches as high as 94.40, while on the MR dataset, it reaches 86.95. Notably, compared to the renowned nnU-Net, SpineMamba achieves superior segmentation performance, exceeding it by up to 2 percentage points. This underscores its accuracy, robustness, and excellent generalization capabilities.

Zhiqing Zhang, Guojia Fan, Tianyong Liu et al.

Medical image segmentation is critical for diagnosing and treating spinal disorders. However, the presence of high noise, ambiguity, and uncertainty makes this task highly challenging. Factors such as unclear anatomical boundaries, inter-class similarities, and irrational annotations contribute to this challenge. Achieving both accurate and diverse segmentation templates is essential to support radiologists in clinical practice. In recent years, denoising diffusion probabilistic modeling (DDPM) has emerged as a prominent research topic in computer vision. It has demonstrated effectiveness in various vision tasks, including image deblurring, super-resolution, anomaly detection, and even semantic representation generation at the pixel level. Despite the robustness of existing diffusion models in visual generation tasks, they still struggle with discrete masks and their various effects. To address the need for accurate and diverse spine medical image segmentation templates, we propose an end-to-end framework called VerseDiff-UNet, which leverages the denoising diffusion probabilistic model (DDPM). Our approach integrates the diffusion model into a standard U-shaped architecture. At each step, we combine the noise-added image with the labeled mask to guide the diffusion direction accurately towards the target region. Furthermore, to capture specific anatomical a priori information in medical images, we incorporate a shape a priori module. This module efficiently extracts structural semantic information from the input spine images. We evaluate our method on a single dataset of spine images acquired through X-ray imaging. Our results demonstrate that VerseDiff-UNet significantly outperforms other state-of-the-art methods in terms of accuracy while preserving the natural features and variations of anatomy.