Yu Zeng

Yu Zeng, Zhe Lin, Jianming Zhang et al.

We propose a new framework for conditional image synthesis from semantic layouts of any precision levels, ranging from pure text to a 2D semantic canvas with precise shapes. More specifically, the input layout consists of one or more semantic regions with free-form text descriptions and adjustable precision levels, which can be set based on the desired controllability. The framework naturally reduces to text-to-image (T2I) at the lowest level with no shape information, and it becomes segmentation-to-image (S2I) at the highest level. By supporting the levels in-between, our framework is flexible in assisting users of different drawing expertise and at different stages of their creative workflow. We introduce several novel techniques to address the challenges coming with this new setup, including a pipeline for collecting training data; a precision-encoded mask pyramid and a text feature map representation to jointly encode precision level, semantics, and composition information; and a multi-scale guided diffusion model to synthesize images. To evaluate the proposed method, we collect a test dataset containing user-drawn layouts with diverse scenes and styles. Experimental results show that the proposed method can generate high-quality images following the layout at given precision, and compares favorably against existing methods. Project page \url{https://zengxianyu.github.io/scenec/}

Yu Zeng, Zhe Lin, Vishal M. Patel

Previous works on image inpainting mainly focus on inpainting background or partially missing objects, while the problem of inpainting an entire missing object remains unexplored. This work studies a new image inpainting task, i.e. shape-guided object inpainting. Given an incomplete input image, the goal is to fill in the hole by generating an object based on the context and implicit guidance given by the hole shape. Since previous methods for image inpainting are mainly designed for background inpainting, they are not suitable for this task. Therefore, we propose a new data preparation method and a novel Contextual Object Generator (CogNet) for the object inpainting task. On the data side, we incorporate object priors into training data by using object instances as holes. The CogNet has a two-stream architecture that combines the standard bottom-up image completion process with a top-down object generation process. A predictive class embedding module bridges the two streams by predicting the class of the missing object from the bottom-up features, from which a semantic object map is derived as the input of the top-down stream. Experiments demonstrate that the proposed method can generate realistic objects that fit the context in terms of both visual appearance and semantic meanings. Code can be found at the project page \url{https://zengxianyu.github.io/objpaint}

Haipeng Li, Dingrui Liu, Yu Zeng et al.

Accurate segmentation of lesions is crucial for diagnosis and treatment of early esophageal cancer (EEC). However, neither traditional nor deep learning-based methods up to today can meet the clinical requirements, with the mean Dice score - the most important metric in medical image analysis - hardly exceeding 0.75. In this paper, we present a novel deep learning approach for segmenting EEC lesions. Our approach stands out for its uniqueness, as it relies solely on a single image coming from one patient, forming the so-called "You-Only-Have-One" (YOHO) framework. On one hand, this "one-image-one-network" learning ensures complete patient privacy as it does not use any images from other patients as the training data. On the other hand, it avoids nearly all generalization-related problems since each trained network is applied only to the input image itself. In particular, we can push the training to "over-fitting" as much as possible to increase the segmentation accuracy. Our technical details include an interaction with clinical physicians to utilize their expertise, a geometry-based rendering of a single lesion image to generate the training set (the \emph{biggest} novelty), and an edge-enhanced UNet. We have evaluated YOHO over an EEC data-set created by ourselves and achieved a mean Dice score of 0.888, which represents a significant advance toward clinical applications.

Yu Zeng, Mo Zhou, Yuan Xue et al.

Recent advances in deep generative models have led to the development of methods capable of synthesizing high-quality, realistic images. These models pose threats to society due to their potential misuse. Prior research attempted to mitigate these threats by detecting generated images, but the varying traces left by different generative models make it challenging to create a universal detector capable of generalizing to new, unseen generative models. In this paper, we propose to inject a universal adversarial signature into an arbitrary pre-trained generative model, in order to make its generated contents more detectable and traceable. First, the imperceptible optimal signature for each image can be found by a signature injector through adversarial training. Subsequently, the signature can be incorporated into an arbitrary generator by fine-tuning it with the images processed by the signature injector. In this way, the detector corresponding to the signature can be reused for any fine-tuned generator for tracking the generator identity. The proposed method is validated on the FFHQ and ImageNet datasets with various state-of-the-art generative models, consistently showing a promising detection rate. Code will be made publicly available at \url{https://github.com/zengxianyu/genwm}.

Xiang Bai, Hanchen Wang, Liya Ma et al.

Artificial intelligence (AI) provides a promising substitution for streamlining COVID-19 diagnoses. However, concerns surrounding security and trustworthiness impede the collection of large-scale representative medical data, posing a considerable challenge for training a well-generalised model in clinical practices. To address this, we launch the Unified CT-COVID AI Diagnostic Initiative (UCADI), where the AI model can be distributedly trained and independently executed at each host institution under a federated learning framework (FL) without data sharing. Here we show that our FL model outperformed all the local models by a large yield (test sensitivity /specificity in China: 0.973/0.951, in the UK: 0.730/0.942), achieving comparable performance with a panel of professional radiologists. We further evaluated the model on the hold-out (collected from another two hospitals leaving out the FL) and heterogeneous (acquired with contrast materials) data, provided visual explanations for decisions made by the model, and analysed the trade-offs between the model performance and the communication costs in the federated training process. Our study is based on 9,573 chest computed tomography scans (CTs) from 3,336 patients collected from 23 hospitals located in China and the UK. Collectively, our work advanced the prospects of utilising federated learning for privacy-preserving AI in digital health.