Jeroen Audenaert

Pablo Mercader-Perez, Carolina Cuesta-Lazaro, Daniel Muthukrishna et al.

Data collected from the physical world is always a combination of multiple sources: an underlying signal from the physical process of interest and a signal from measurement-dependent artifacts from the sensor or instrument. This secondary signal acts as a confounding factor, limiting our ability to extract information about the physics underlying the phenomena we observe. Furthermore, it complicates the combination of observations in heterogeneous or multi-instrument settings. We propose a deep learning framework that leverages overlapping observations, a dual-encoder architecture, and a counterfactual generation objective to disentangle these factors of variation. The resulting representations explicitly separate intrinsic signals from sensor-specific distortions and noise, and can be used for counterfactual view generation, parameter inference unconfounded by measurement distortions, and instrument-independent similarity search. We demonstrate the effectiveness of our approach on astrophysical galaxy images from the DESI Legacy Imaging Survey (Legacy) and the Hyper Suprime-Cam (HSC) Survey as a representative multi-instrument setting. This framework provides a general recipe for scientific and multi-modal self-supervised pretraining: construct training pairs from overlapping observations of the same physical system, treat sensor- or modality-specific effects as augmentations, and learn invariant representations through counterfactual generation.

Jeroen Audenaert, Daniel Muthukrishna, Paul F. Gregory et al.

Foundation models for structured time series data must contend with a fundamental challenge: observations often conflate the true underlying physical phenomena with systematic distortions introduced by measurement instruments. This entanglement limits model generalization, especially in heterogeneous or multi-instrument settings. We present a causally-motivated foundation model that explicitly disentangles physical and instrumental factors using a dual-encoder architecture trained with structured contrastive learning. Leveraging naturally occurring observational triplets (i.e., where the same target is measured under varying conditions, and distinct targets are measured under shared conditions) our model learns separate latent representations for the underlying physical signal and instrument effects. Evaluated on simulated astronomical time series designed to resemble the complexity of variable stars observed by missions like NASA's Transiting Exoplanet Survey Satellite (TESS), our method significantly outperforms traditional single-latent space foundation models on downstream prediction tasks, particularly in low-data regimes. These results demonstrate that our model supports key capabilities of foundation models, including few-shot generalization and efficient adaptation, and highlight the importance of encoding causal structure into representation learning for structured data.

Rithwik Gupta, Daniel Muthukrishna, Jeroen Audenaert

Astronomical time-series analysis faces a critical limitation: the scarcity of labeled observational data. We present a pre-training approach that leverages simulations, significantly reducing the need for labeled examples from real observations. Our models, trained on simulated data from multiple astronomical surveys (ZTF and LSST), learn generalizable representations that transfer effectively to downstream tasks. Using classifier-based architectures enhanced with contrastive and adversarial objectives, we create domain-agnostic models that demonstrate substantial performance improvements over baseline methods in classification, redshift estimation, and anomaly detection when fine-tuned with minimal real data. Remarkably, our models exhibit effective zero-shot transfer capabilities, achieving comparable performance on future telescope (LSST) simulations when trained solely on existing telescope (ZTF) data. Furthermore, they generalize to very different astronomical phenomena (namely variable stars from NASA's \textit{Kepler} telescope) despite being trained on transient events, demonstrating cross-domain capabilities. Our approach provides a practical solution for building general models when labeled data is scarce, but domain knowledge can be encoded in simulations.