Chongwen Lyu

Chengxuan Qian, Kai Han, Jiaxin Liu et al.

Multimodal learning integrates complementary information from diverse modalities to enhance the decision-making process. However, the potential of multimodal collaboration remains under-exploited due to disparities in data quality and modality representation capabilities. To address this, we introduce DynCIM, a novel dynamic curriculum learning framework designed to quantify the inherent imbalances from both sample and modality perspectives. DynCIM employs a sample-level curriculum to dynamically assess each sample's difficulty according to prediction deviation, consistency, and stability, while a modality-level curriculum measures modality contributions from global and local. Furthermore, a gating-based dynamic fusion mechanism is introduced to adaptively adjust modality contributions, minimizing redundancy and optimizing fusion effectiveness. Extensive experiments on six multimodal benchmarking datasets, spanning both bimodal and trimodal scenarios, demonstrate that DynCIM consistently outperforms state-of-the-art methods. Our approach effectively mitigates modality and sample imbalances while enhancing adaptability and robustness in multimodal learning tasks. Our code is available at https://github.com/Raymond-Qiancx/DynCIM.

Kai Han, Chongwen Lyu, Lele Ma et al.

Clinicians usually combine information from multiple sources to achieve the most accurate diagnosis, and this has sparked increasing interest in leveraging multimodal deep learning for diagnosis. However, in real clinical scenarios, due to differences in incidence rates, multimodal medical data commonly face the issue of class imbalance, which makes it difficult to adequately learn the features of minority classes. Most existing methods tackle this issue with resampling or loss reweighting, but they are prone to overfitting or underfitting and fail to capture cross-modal interactions. Therefore, we propose a Curriculum Learning framework for Imbalanced Multimodal Diagnosis (CLIMD). Specifically, we first design multimodal curriculum measurer that combines two indicators, intra-modal confidence and inter-modal complementarity, to enable the model to focus on key samples and gradually adapt to complex category distributions. Additionally, a class distribution-guided training scheduler is introduced, which enables the model to progressively adapt to the imbalanced class distribution during training. Extensive experiments on multiple multimodal medical datasets demonstrate that the proposed method outperforms state-of-the-art approaches across various metrics and excels in handling imbalanced multimodal medical data. Furthermore, as a plug-and-play CL framework, CLIMD can be easily integrated into other models, offering a promising path for improving multimodal disease diagnosis accuracy. Code is publicly available at https://github.com/KHan-UJS/CLIMD.

Chengxuan Qian, Kai Han, Jianxia Ding et al.

Deep learning has shown remarkable success in medical image analysis, but its reliance on large volumes of high-quality labeled data limits its applicability. While noisy labeled data are easier to obtain, directly incorporating them into training can degrade model performance. To address this challenge, we propose a Mean Teacher-based Adaptive Label Correction (ALC) self-ensemble framework for robust medical image segmentation with noisy labels. The framework leverages the Mean Teacher architecture to ensure consistent learning under noise perturbations. It includes an adaptive label refinement mechanism that dynamically captures and weights differences across multiple disturbance versions to enhance the quality of noisy labels. Additionally, a sample-level uncertainty-based label selection algorithm is introduced to prioritize high-confidence samples for network updates, mitigating the impact of noisy annotations. Consistency learning is integrated to align the predictions of the student and teacher networks, further enhancing model robustness. Extensive experiments on two public datasets demonstrate the effectiveness of the proposed framework, showing significant improvements in segmentation performance. By fully exploiting the strengths of the Mean Teacher structure, the ALC framework effectively processes noisy labels, adapts to challenging scenarios, and achieves competitive results compared to state-of-the-art methods.

Zhe Liu, Kai Han, Siqi Ma et al.

Computer-aided diagnosis (CAD) technology can assist clinicians in evaluating liver lesions and intervening with treatment in time. Although CAD technology has advanced in recent years, the application scope of existing datasets remains relatively limited, typically supporting only single tasks, which has somewhat constrained the development of CAD technology. To address the above limitation, in this paper, we construct a multi-task liver dataset (LiMT) used for liver and tumor segmentation, multi-label lesion classification, and lesion detection based on arterial phase-enhanced computed tomography (CT), potentially providing an exploratory solution that is able to explore the correlation between tasks and does not need to worry about the heterogeneity between task-specific datasets during training. The dataset includes CT volumes from 150 different cases, comprising four types of liver diseases as well as normal cases. Each volume has been carefully annotated and calibrated by experienced clinicians. This public multi-task dataset may become a valuable resource for the medical imaging research community in the future. In addition, this paper not only provides relevant baseline experimental results but also reviews existing datasets and methods related to liver-related tasks. Our dataset is available at https://drive.google.com/drive/folders/1l9HRK13uaOQTNShf5pwgSz3OTanWjkag?usp=sharing.

Kai Han, Siqi Ma, Chengxuan Qian et al.

Accurate segmentation of tumors and adjacent normal tissues in medical images is essential for surgical planning and tumor staging. Although foundation models generally perform well in segmentation tasks, they often struggle to focus on foreground areas in complex, low-contrast backgrounds, where some malignant tumors closely resemble normal organs, complicating contextual differentiation. To address these challenges, we propose the Foreground-Aware Spectrum Segmentation (FASS) framework. First, we introduce a foreground-aware module to amplify the distinction between background and the entire volume space, allowing the model to concentrate more effectively on target areas. Next, a feature-level frequency enhancement module, based on wavelet transform, extracts discriminative high-frequency features to enhance boundary recognition and detail perception. Eventually, we introduce an edge constraint module to preserve geometric continuity in segmentation boundaries. Extensive experiments on multiple medical datasets demonstrate superior performance across all metrics, validating the effectiveness of our framework, particularly in robustness under complex conditions and fine structure recognition. Our framework significantly enhances segmentation of low-contrast images, paving the way for applications in more diverse and complex medical imaging scenarios.