Yixuan Ye

Liang Peng, Haopeng Liu, Yixuan Ye et al.

Unsupervised cell type identification is crucial for uncovering and characterizing heterogeneous populations in single cell omics studies. Although a range of clustering methods have been developed, most focus exclusively on intrinsic cellular structure and ignore the pivotal role of cell-gene associations, which limits their ability to distinguish closely related cell types. To this end, we propose a Refinement Contrastive Learning framework (scRCL) that explicitly incorporates cell-gene interactions to derive more informative representations. Specifically, we introduce two contrastive distribution alignment components that reveal reliable intrinsic cellular structures by effectively exploiting cell-cell structural relationships. Additionally, we develop a refinement module that integrates gene-correlation structure learning to enhance cell embeddings by capturing underlying cell-gene associations. This module strengthens connections between cells and their associated genes, refining the representation learning to exploiting biologically meaningful relationships. Extensive experiments on several single-cell RNA-seq and spatial transcriptomics benchmark datasets demonstrate that our method consistently outperforms state-of-the-art baselines in cell-type identification accuracy. Moreover, downstream biological analyses confirm that the recovered cell populations exhibit coherent gene-expression signatures, further validating the biological relevance of our approach. The code is available at https://github.com/THPengL/scRCL.

Yixuan Ye, Ce Wang, Wanjie Sun et al.

Remote-sensing (RS) image compression at extremely low bitrates has always been a challenging task in practical scenarios like edge device storage and narrow bandwidth transmission. Generative models including VAEs and GANs have been explored to compress RS images into extremely low-bitrate streams. However, these generative models struggle to reconstruct visually plausible images due to the highly ill-posed nature of extremely low-bitrate image compression. To this end, we propose an image compression framework that utilizes a pre-trained diffusion model with powerful natural image priors to achieve high-realism reconstructions. However, diffusion models tend to hallucinate small structures and textures due to the significant information loss at limited bitrates. Thus, we introduce vector maps as semantic and structural guidance and propose a novel image compression approach named Map-Assisted Generative Compression (MAGC). MAGC employs a two-stage pipeline to compress and decompress RS images at extremely low bitrates. The first stage maps an image into a latent representation, which is then further compressed in a VAE architecture to save bitrates and serves as implicit guidance in the subsequent diffusion process. The second stage conducts a conditional diffusion model to generate a visually pleasing and semantically accurate result using implicit guidance and explicit semantic guidance. Quantitative and qualitative comparisons show that our method outperforms standard codecs and other learning-based methods in terms of perceptual quality and semantic accuracy. The dataset and code will be publicly available at https://github.com/WHUyyx/MAGC.

Qiwei Liang, Boyang Cai, Minghao Lai et al.

Despite strong results on recognition and segmentation, current 3D visual pre-training methods often underperform on robotic manipulation. We attribute this gap to two factors: the lack of state-action-state dynamics modeling and the unnecessary redundancy of explicit geometric reconstruction. We introduce AFRO, a self-supervised framework that learns dynamics-aware 3D representations without action or reconstruction supervision. AFRO casts state prediction as a generative diffusion process and jointly models forward and inverse dynamics in a shared latent space to capture causal transition structure. To prevent feature leakage in action learning, we employ feature differencing and inverse-consistency supervision, improving the quality and stability of visual features. When combined with Diffusion Policy, AFRO substantially increases manipulation success rates across 16 simulated and 4 real-world tasks, outperforming existing pre-training approaches. The framework also scales favorably with data volume and task complexity. Qualitative visualizations indicate that AFRO learns semantically rich, discriminative features, offering an effective pre-training solution for 3D representation learning in robotics. Project page: https://kolakivy.github.io/AFRO/