Feng Luo

Mary Aiyetigbo, Alexander Korte, Ethan Anderson et al.

In this paper, we introduce a novel unsupervised network to denoise microscopy videos featured by image sequences captured by a fixed location microscopy camera. Specifically, we propose a DeepTemporal Interpolation method, leveraging a temporal signal filter integrated into the bottom CNN layers, to restore microscopy videos corrupted by unknown noise types. Our unsupervised denoising architecture is distinguished by its ability to adapt to multiple noise conditions without the need for pre-existing noise distribution knowledge, addressing a significant challenge in real-world medical applications. Furthermore, we evaluate our denoising framework using both real microscopy recordings and simulated data, validating our outperforming video denoising performance across a broad spectrum of noise scenarios. Extensive experiments demonstrate that our unsupervised model consistently outperforms state-of-the-art supervised and unsupervised video denoising techniques, proving especially effective for microscopy videos.

Mary Aiyetigbo, Wanqi Yuan, Feng Luo et al.

High-resolution (HR) videos play a crucial role in many computer vision applications. Although existing video restoration (VR) methods can significantly enhance video quality by exploiting temporal information across video frames, they are typically trained for fixed upscaling factors and lack the flexibility to handle scales or degradations beyond their training distribution. In this paper, we introduce VR-INR, a novel video restoration approach based on Implicit Neural Representations (INRs) that is trained only on a single upscaling factor ($\times 4$) but generalizes effectively to arbitrary, unseen super-resolution scales at test time. Notably, VR-INR also performs zero-shot denoising on noisy input, despite never having seen noisy data during training. Our method employs a hierarchical spatial-temporal-texture encoding framework coupled with multi-resolution implicit hash encoding, enabling adaptive decoding of high-resolution and noise-suppressed frames from low-resolution inputs at any desired magnification. Experimental results show that VR-INR consistently maintains high-quality reconstructions at unseen scales and noise during training, significantly outperforming state-of-the-art approaches in sharpness, detail preservation, and denoising efficacy.