Jiaqi Lv

Runkai Li, Jia Xiong, Xiuyuan He et al.

High-Level Synthesis (HLS) improves IC development productivity by enabling hardware design from C-like languages. However, strict coding constraints and design-specific optimizations limit its widespread adoption. While recent efforts employ large language models (LLMs) to assist HLS design, they often struggle with synthesizability rules and directive semantics. To this end, we introduce ChatHLS, a multi-agent HLS design framework that leverages specialized LLMs for automated debugging and directive tuning. ChatHLS incorporates an adaptive error case expansion mechanism, combined with a reasoning-to-instruction analysis method to accurately diagnose HLS errors. To optimize hardware performance, it enables QoR-aware reasoning to learn the impact of HLS directives on the quality of results (QoR). Experimental results demonstrate that ChatHLS outperforms Gemini-3-pro with a 32.6% relative improvement in debugging, while achieving significant speedups across various HLS kernels and neural network accelerators. These results underscore the potential of ChatHLS for agile hardware development.

Noorul Wahab, Ethar Alzaid, Jiaqi Lv et al.

Accurate prediction of time-to-event outcomes is a central challenge in oncology, with significant implications for treatment planning and patient management. In this work, we present ModaliSurv, a multimodal deep survival model utilising DeepHit with a projection layer and inter-modality cross-attention, which integrates heterogeneous patient data, including clinical, MRI, RNA-seq and whole-slide pathology features. The model is designed to capture complementary prognostic signals across modalities and estimate individualised time-to-biochemical recurrence in prostate cancer and time-to-cancer recurrence in bladder cancer. Our approach was evaluated in the context of the CHIMERA Grand Challenge, across two of the three provided tasks. For Task 1 (prostate cancer bio-chemical recurrence prediction), the proposed framework achieved a concordance index (C-index) of 0.843 on 5-folds cross-validation and 0.818 on CHIMERA development set, demonstrating robust discriminatory ability. For Task 3 (bladder cancer recurrence prediction), the model obtained a C-index of 0.662 on 5-folds cross-validation and 0.457 on development set, highlighting its adaptability and potential for clinical translation. These results suggest that leveraging multimodal integration with deep survival learning provides a promising pathway toward personalised risk stratification in prostate and bladder cancer. Beyond the challenge setting, our framework is broadly applicable to survival prediction tasks involving heterogeneous biomedical data.