Kathleen M. Jagodnik

Nirmal Gelal, Chloe Snow, Ambyr Rios et al.

High school English Literature teachers often encounter barriers to assembling diverse, thematically aligned text sets due to limited planning time and pedagogical resources. To address this need, we present T-TExTS (Teaching Text Expansion for Teacher Scaffolding), a knowledge graph (KG)-based recommendation system that suggests literature texts based on pedagogical merit rather than surface-level metadata. We construct a domain-specific ontology using the Knowledge Acquisition and Representation Methodology (KNARM), instantiate it as a knowledge graph with separate Terminological Box (TBox) and Assertional Box (ABox) components, and evaluate four graph embedding strategies (DeepWalk, biased random walk, hybrid embedding, and Node2Vec) across three dataset configurations (98, 196, and 351 texts) and two relation-weighting schemes. The experimental results reveal that traversal-level expert weighting alone does not outperform algorithmic structural tuning: Node2Vec achieves the highest Area Under the Curve (AUC) at every dataset size (0.9642--0.9750) and the strongest ranking metrics (Hits@K, MRR, nDCG) at larger scales. Combining structural and pedagogical signals through embedding concatenation, however, preserves both interpretability and competitive ranking quality, with the hybrid model maintaining a high AUC across all scales (0.9122--0.9350) and remaining within a few percentage points of Node2Vec on every ranking metric. These findings highlight the value of ontology-driven knowledge graph embeddings for educational recommendation systems and demonstrate that T-TExTS can meaningfully ease the burden of English Literature text selection for secondary educators, supporting more informed and inclusive curricular decisions. The source code for T-TExTS is available at https://github.com/koncordantlab/TTExTS.

Aryan Singh Dalal, Maria Baloch, Asiyah Yu Lin et al.

The Semantic Web standardizes concept meaning for humans and machines, enabling machine-operable content and consistent interpretation that improves advanced analytics. Reusing ontologies speeds development and enforces consistency, yet selecting the optimal choice is challenging because authors lack systematic selection criteria and often rely on intuition that is difficult to justify, limiting reuse. To solve this, WiseOWL is proposed, a methodology with scoring and guidance to select ontologies for reuse. It scores four metrics: (i) Well-Described, measuring documentation coverage; (ii) Well-Defined, using state-of-the-art embeddings to assess label-definition alignment; (iii) Connection, capturing structural interconnectedness; and (iv) Hierarchical Breadth, reflecting hierarchical balance. WiseOWL outputs normalized 0-10 scores with actionable feedback. Implemented as a Streamlit app, it ingests OWL format, converts to RDF Turtle, and provides interactive visualizations. Evaluation across six ontologies, including the Plant Ontology (PO), Gene Ontology (GO), Semanticscience Integrated Ontology (SIO), Food Ontology (FoodON), Dublin Core (DC), and GoodRelations, demonstrates promising effectiveness.

Alon Bartal, Kathleen M. Jagodnik, Nava Pliskin et al.

Adverse side effects (ASEs) of drugs, revealed after FDA approval, pose a threat to patient safety. To promptly detect overlooked ASEs, we developed a digital health methodology capable of analyzing massive public data from social media, published clinical research, manufacturers' reports, and ChatGPT. We uncovered ASEs associated with the glucagon-like peptide 1 receptor agonists (GLP-1 RA), a market expected to grow exponentially to $133.5 billion USD by 2030. Using a Named Entity Recognition (NER) model, our method successfully detected 21 potential ASEs overlooked upon FDA approval, including irritability and numbness. Our data-analytic approach revolutionizes the detection of unreported ASEs associated with newly deployed drugs, leveraging cutting-edge AI-driven social media analytics. It can increase the safety of new drugs in the marketplace by unlocking the power of social media to support regulators and manufacturers in the rapid discovery of hidden ASE risks.