Weiyang He

Chaohui Xu, Qi Cui, Jinxin Dong et al.

Illegitimate reproduction, distribution and derivation of Deep Neural Network (DNN) models can inflict economic loss, reputation damage and even privacy infringement. Passive DNN intellectual property (IP) protection methods such as watermarking and fingerprinting attempt to prove the ownership upon IP violation, but they are often too late to stop catastrophic damage of IP abuse and too feeble against strong adversaries. In this paper, we propose IDEA, an Inverse Domain Expert Adaptation based proactive DNN IP protection method featuring active authorization and source traceability. IDEA generalizes active authorization as an inverse problem of domain adaptation. The multi-adaptive optimization is solved by a mixture-of-experts model with one real and two fake experts. The real expert re-optimizes the source model to correctly classify test images with a unique model user key steganographically embedded. The fake experts are trained to output random prediction on test images without or with incorrect user key embedded by minimizing their mutual information (MI) with the real expert. The MoE model is knowledge distilled into a unified protected model to avoid leaking the expert model features by maximizing their MI with additional multi-layer attention and contrastive representation loss optimization. IDEA not only prevents unauthorized users without the valid key to access the functional model, but also enable the model owner to validate the deployed model and trace the source of IP infringement. We extensively evaluate IDEA on five datasets and four DNN models to demonstrate its effectiveness in authorization control, culprit tracing success rate, and robustness against various attacks.

Fengtao Zhou, Yingxue Xu, Yanfen Cui et al.

Gastric cancer (GC) is a prevalent malignancy worldwide, ranking as the fifth most common cancer with over 1 million new cases and 700 thousand deaths in 2020. Locally advanced gastric cancer (LAGC) accounts for approximately two-thirds of GC diagnoses, and neoadjuvant chemotherapy (NACT) has emerged as the standard treatment for LAGC. However, the effectiveness of NACT varies significantly among patients, with a considerable subset displaying treatment resistance. Ineffective NACT not only leads to adverse effects but also misses the optimal therapeutic window, resulting in lower survival rate. However, existing multimodal learning methods assume the availability of all modalities for each patient, which does not align with the reality of clinical practice. The limited availability of modalities for each patient would cause information loss, adversely affecting predictive accuracy. In this study, we propose an incomplete multimodal data integration framework for GC (iMD4GC) to address the challenges posed by incomplete multimodal data, enabling precise response prediction and survival analysis. Specifically, iMD4GC incorporates unimodal attention layers for each modality to capture intra-modal information. Subsequently, the cross-modal interaction layers explore potential inter-modal interactions and capture complementary information across modalities, thereby enabling information compensation for missing modalities. To evaluate iMD4GC, we collected three multimodal datasets for GC study: GastricRes (698 cases) for response prediction, GastricSur (801 cases) for survival analysis, and TCGA-STAD (400 cases) for survival analysis. The scale of our datasets is significantly larger than previous studies. The iMD4GC achieved impressive performance with an 80.2% AUC on GastricRes, 71.4% C-index on GastricSur, and 66.1% C-index on TCGA-STAD, significantly surpassing other compared methods.