Lin Luo

Wenkang Qin, Rui Xu, Peixiang Huang et al.

Pathological captioning of Whole Slide Images (WSIs), though is essential in computer-aided pathological diagnosis, has rarely been studied due to the limitations in datasets and model training efficacy. In this paper, we propose a new paradigm Subtype-guided Masked Transformer (SGMT) for pathological captioning based on Transformers, which treats a WSI as a sequence of sparse patches and generates an overall caption sentence from the sequence. An accompanying subtype prediction is introduced into SGMT to guide the training process and enhance the captioning accuracy. We also present an Asymmetric Masked Mechansim approach to tackle the large size constraint of pathological image captioning, where the numbers of sequencing patches in SGMT are sampled differently in the training and inferring phases, respectively. Experiments on the PatchGastricADC22 dataset demonstrate that our approach effectively adapts to the task with a transformer-based model and achieves superior performance than traditional RNN-based methods. Our codes are to be made available for further research and development.

Lin Luo, Xin Wang, Bojia Zi et al.

Large pre-trained Vision-Language Models (VLMs) such as Contrastive Language-Image Pre-training (CLIP) have been shown to be susceptible to adversarial attacks, raising concerns about their deployment in safety-critical applications like autonomous driving and medical diagnosis. One promising approach for robustifying pre-trained VLMs is Adversarial Prompt Tuning (APT), which applies adversarial training during the process of prompt tuning. However, existing APT methods are mostly single-modal methods that design prompt(s) for only the visual or textual modality, limiting their effectiveness in either robustness or clean accuracy. In this work, we propose Adversarial Prompt Distillation (APD), a bimodal knowledge distillation framework that enhances APT by integrating it with multi-modal knowledge transfer. APD optimizes prompts for both visual and textual modalities while distilling knowledge from a clean pre-trained teacher CLIP model. Extensive experiments on multiple benchmark datasets demonstrate the superiority of our APD method over the current state-of-the-art APT methods in terms of both adversarial robustness and clean accuracy. The effectiveness of APD also validates the possibility of using a non-robust teacher to improve the generalization and robustness of fine-tuned VLMs.