Yingjie Huang

Junhao Dong, Dejia Liu, Ruiqi Ding et al.

Transjugular intrahepatic portosystemic shunt (TIPS) is an established procedure for portal hypertension, but provides variable survival outcomes and frequent overt hepatic encephalopathy (OHE), indicating the necessity of accurate preoperative prognostic modeling. Current studies typically build machine learning models from preoperative CT images or clinical characteristics, but face three key challenges: (1) labor-intensive region-of-interest (ROI) annotation, (2) poor reliability and generalizability of unimodal methods, and (3) incomplete assessment from single-endpoint prediction. Moreover, the lack of publicly accessible datasets constrains research in this field. Therefore, we present MultiTIPS, the first public multi-center dataset for TIPS prognosis, and propose a novel multimodal prognostic framework based on it. The framework comprises three core modules: (1) dual-option segmentation, which integrates semi-supervised and foundation model-based pipelines to achieve robust ROI segmentation with limited annotations and facilitate subsequent feature extraction; (2) multimodal interaction, where three techniques, multi-grained radiomics attention (MGRA), progressive orthogonal disentanglement (POD), and clinically guided prognostic enhancement (CGPE), are introduced to enable cross-modal feature interaction and complementary representation integration, thus improving model accuracy and robustness; and (3) multi-task prediction, where a staged training strategy is used to perform stable optimization of survival, portal pressure gradient (PPG), and OHE prediction for comprehensive prognostic assessment. Extensive experiments on MultiTIPS demonstrate the superiority of the proposed method over state-of-the-art approaches, along with strong cross-domain generalization and interpretability, indicating its promise for clinical application. The dataset and code are available.

Huiqi Wu, Jianbo Mei, Yingjie Huang et al.

In recent years, significant advancements have been made in text-driven 3D content generation. However, several challenges remain. In practical applications, users often provide extremely simple text inputs while expecting high-quality 3D content. Generating optimal results from such minimal text is a difficult task due to the strong dependency of text-to-3D models on the quality of input prompts. Moreover, the generation process exhibits high variability, making it difficult to control. Consequently, multiple iterations are typically required to produce content that meets user expectations, reducing generation efficiency. To address this issue, we propose GPT-4V for self-optimization, which significantly enhances the efficiency of generating satisfactory content in a single attempt. Furthermore, the controllability of text-to-3D generation methods has not been fully explored. Our approach enables users to not only provide textual descriptions but also specify additional conditions, such as style, edges, scribbles, poses, or combinations of multiple conditions, allowing for more precise control over the generated 3D content. Additionally, during training, we effectively integrate multi-view information, including multi-view depth, masks, features, and images, to address the common Janus problem in 3D content generation. Extensive experiments demonstrate that our method achieves robust generalization, facilitating the efficient and controllable generation of high-quality 3D content.