Jianzhu Ma

Dongting Li, Xingyu Chen, Qianyang Wu et al.

Humanoid robots show promise for complex whole-body tasks in unstructured environments. Although Human-Object Interaction (HOI) has advanced, most methods focus on fully actuated objects rigidly coupled to the robot, ignoring underactuated objects with independent dynamics and non-holonomic constraints. These introduce control challenges from coupling forces and occlusions. We present HAIC, a unified framework for robust interaction across diverse object dynamics without external state estimation. Our key contribution is a dynamics predictor that estimates high-order object states (velocity, acceleration) solely from proprioceptive history. These predictions are projected onto static geometric priors to form a spatially grounded dynamic occupancy map, enabling the policy to infer collision boundaries and contact affordances in blind spots. We use asymmetric fine-tuning, where a world model continuously adapts to the student policy's exploration, ensuring robust state estimation under distribution shifts. Experiments on a humanoid robot show HAIC achieves high success rates in agile tasks (skateboarding, cart pushing/pulling under various loads) by proactively compensating for inertial perturbations, and also masters multi-object long-horizon tasks like carrying a box across varied terrain by predicting the dynamics of multiple objects.

Ruidong Wu, Ruihan Guo, Rui Wang et al.

Despite the striking success of general protein folding models such as AlphaFold2(AF2, Jumper et al. (2021)), the accurate computational modeling of antibody-antigen complexes remains a challenging task. In this paper, we first analyze AF2's primary loss function, known as the Frame Aligned Point Error (FAPE), and raise a previously overlooked issue that FAPE tends to face gradient vanishing problem on high-rotational-error targets. To address this fundamental limitation, we propose a novel geodesic loss called Frame Aligned Frame Error (FAFE, denoted as F2E to distinguish from FAPE), which enables the model to better optimize both the rotational and translational errors between two frames. We then prove that F2E can be reformulated as a group-aware geodesic loss, which translates the optimization of the residue-to-residue error to optimizing group-to-group geodesic frame distance. By fine-tuning AF2 with our proposed new loss function, we attain a correct rate of 52.3\% (DockQ $>$ 0.23) on an evaluation set and 43.8\% correct rate on a subset with low homology, with substantial improvement over AF2 by 182\% and 100\% respectively.