Fengkuan Ma

Wentao Lei, Jinting Wang, Fengji Ma et al.

Human video generation is a dynamic and rapidly evolving task that aims to synthesize 2D human body video sequences with generative models given control conditions such as text, audio, and pose. With the potential for wide-ranging applications in film, gaming, and virtual communication, the ability to generate natural and realistic human video is critical. Recent advancements in generative models have laid a solid foundation for the growing interest in this area. Despite the significant progress, the task of human video generation remains challenging due to the consistency of characters, the complexity of human motion, and difficulties in their relationship with the environment. This survey provides a comprehensive review of the current state of human video generation, marking, to the best of our knowledge, the first extensive literature review in this domain. We start with an introduction to the fundamentals of human video generation and the evolution of generative models that have facilitated the field's growth. We then examine the main methods employed for three key sub-tasks within human video generation: text-driven, audio-driven, and pose-driven motion generation. These areas are explored concerning the conditions that guide the generation process. Furthermore, we offer a collection of the most commonly utilized datasets and the evaluation metrics that are crucial in assessing the quality and realism of generated videos. The survey concludes with a discussion of the current challenges in the field and suggests possible directions for future research. The goal of this survey is to offer the research community a clear and holistic view of the advancements in human video generation, highlighting the milestones achieved and the challenges that lie ahead.

He Hu, Yucheng Zhou, Juzheng Si et al.

Large language models (LLMs) hold significant potential for mental health support, capable of generating empathetic responses and simulating therapeutic conversations. However, existing LLM-based approaches often lack the clinical grounding necessary for real-world psychological counseling, particularly in explicit diagnostic reasoning aligned with standards like the DSM/ICD and incorporating diverse therapeutic modalities beyond basic empathy or single strategies. To address these critical limitations, we propose PsyLLM, the first large language model designed to systematically integrate both diagnostic and therapeutic reasoning for mental health counseling. To develop PsyLLM, we design a novel automated data synthesis pipeline that processes real-world mental health posts collected from Reddit, where users frequently share psychological distress and seek community support. This pipeline processes real-world mental health posts, generates multi-turn dialogue structures, and leverages LLMs guided by international diagnostic standards (e.g., DSM/ICD) and multiple therapeutic frameworks (e.g., CBT, ACT, psychodynamic) to simulate detailed clinical reasoning processes. Rigorous multi-dimensional filtering ensures the generation of high-quality, clinically aligned dialogue data. In addition, we introduce a new benchmark and evaluation protocol, assessing counseling quality across four key dimensions. Our experiments demonstrate that PsyLLM significantly outperforms state-of-the-art baseline models on this benchmark. The model weights and dataset have been publicly released at https://github.com/Emo-gml/PsyLLM.

Han Zhang, Fengji Ma, Jiamin Su et al.

Prediction for ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) plays a crucial role in drug discovery and development, accelerating the screening and optimization of new drugs. Existing methods primarily rely on single-task learning (STL), which often fails to fully exploit the complementarities between tasks. Besides, it requires more computational resources while training and inference of each task independently. To address these issues, we propose a new unified Quantum-enhanced and task-Weighted Multi-Task Learning (QW-MTL) framework, specifically designed for ADMET classification tasks. Built upon the Chemprop-RDKit backbone, QW-MTL adopts quantum chemical descriptors to enrich molecular representations with additional information about the electronic structure and interactions. Meanwhile, it introduces a novel exponential task weighting scheme that combines dataset-scale priors with learnable parameters to achieve dynamic loss balancing across tasks. To the best of our knowledge, this is the first work to systematically conduct joint multi-task training across all 13 Therapeutics Data Commons (TDC) classification benchmarks, using leaderboard-style data splits to ensure a standardized and realistic evaluation setting. Extensive experimental results show that QW-MTL significantly outperforms single-task baselines on 12 out of 13 tasks, achieving high predictive performance with minimal model complexity and fast inference, demonstrating the effectiveness and efficiency of multi-task molecular learning enhanced by quantum-informed features and adaptive task weighting.