Xinyan Huang

Qingyao Tian, Zhen Chen, Huai Liao et al.

Accurate bronchoscope localization is essential for pulmonary interventions, by providing six degrees of freedom (DOF) in airway navigation. However, the robustness of current vision-based methods is often compromised in clinical practice, and they struggle to perform in real-time and to generalize across cases unseen during training. To overcome these challenges, we propose a novel Probabilistic Airway Navigation System (PANS), leveraging Monte-Carlo method with pose hypotheses and likelihoods to achieve robust and real-time bronchoscope localization. Specifically, our PANS incorporates diverse visual representations (\textit{e.g.}, odometry and landmarks) by leveraging two key modules, including the Depth-based Motion Inference (DMI) and the Bronchial Semantic Analysis (BSA). To generate the pose hypotheses of bronchoscope for PANS, we devise the DMI to accurately propagate the estimation of pose hypotheses over time. Moreover, to estimate the accurate pose likelihood, we devise the BSA module by effectively distinguishing between similar bronchial regions in endoscopic images, along with a novel metric to assess the congruence between estimated depth maps and the segmented airway structure. Under this probabilistic formulation, our PANS is capable of achieving the 6-DOF bronchoscope localization with superior accuracy and robustness. Extensive experiments on the collected pulmonary intervention dataset comprising 10 clinical cases confirm the advantage of our PANS over state-of-the-arts, in terms of both robustness and generalization in localizing deeper airway branches and the efficiency of real-time inference. The proposed PANS reveals its potential to be a reliable tool in the operating room, promising to enhance the quality and safety of pulmonary interventions.

Qingyao Tian, Bingyu Yang, Huai Liao et al.

Vision-language models (VLMs) have recently shown remarkable performance in navigation and localization tasks by leveraging large-scale pretraining for semantic understanding. However, applying VLMs to 6-DoF endoscopic camera localization presents several challenges: 1) the lack of large-scale, high-quality, densely annotated, and localization-oriented vision-language datasets in real-world medical settings; 2) limited capability for fine-grained pose regression; and 3) high computational latency when extracting temporal features from past frames. To address these issues, we first construct BREATH dataset, the largest in-vivo endoscopic localization dataset to date, collected in the complex human airway. Building on this dataset, we propose BREATH-VL, a hybrid framework that integrates semantic cues from VLMs with geometric information from vision-based registration methods for accurate 6-DoF pose estimation. Our motivation lies in the complementary strengths of both approaches: VLMs offer generalizable semantic understanding, while registration methods provide precise geometric alignment. To further enhance the VLM's ability to capture temporal context, we introduce a lightweight context-learning mechanism that encodes motion history as linguistic prompts, enabling efficient temporal reasoning without expensive video-level computation. Extensive experiments demonstrate that the vision-language module delivers robust semantic localization in challenging surgical scenes. Building on this, our BREATH-VL outperforms state-of-the-art vision-only localization methods in both accuracy and generalization, reducing translational error by 25.5% compared with the best-performing baseline, while achieving competitive computational latency.

Qingyao Tian, Huai Liao, Xinyan Huang et al.

Localizing the bronchoscope in real time is essential for ensuring intervention quality. However, most existing methods struggle to balance between speed and generalization. To address these challenges, we present BronchoTrack, an innovative real-time framework for accurate branch-level localization, encompassing lumen detection, tracking, and airway association.To achieve real-time performance, we employ a benchmark lightweight detector for efficient lumen detection. We are the first to introduce multi-object tracking to bronchoscopic localization, mitigating temporal confusion in lumen identification caused by rapid bronchoscope movement and complex airway structures. To ensure generalization across patient cases, we propose a training-free detection-airway association method based on a semantic airway graph that encodes the hierarchy of bronchial tree structures.Experiments on nine patient datasets demonstrate BronchoTrack's localization accuracy of 85.64 \%, while accessing up to the 4th generation of airways.Furthermore, we tested BronchoTrack in an in-vivo animal study using a porcine model, where it successfully localized the bronchoscope into the 8th generation airway.Experimental evaluation underscores BronchoTrack's real-time performance in both satisfying accuracy and generalization, demonstrating its potential for clinical applications.