Rao Kotamarthi

Shuaiwen Leon Song, Bonnie Kruft, Minjia Zhang et al. · microsoft-research

In the upcoming decade, deep learning may revolutionize the natural sciences, enhancing our capacity to model and predict natural occurrences. This could herald a new era of scientific exploration, bringing significant advancements across sectors from drug development to renewable energy. To answer this call, we present DeepSpeed4Science initiative (deepspeed4science.ai) which aims to build unique capabilities through AI system technology innovations to help domain experts to unlock today's biggest science mysteries. By leveraging DeepSpeed's current technology pillars (training, inference and compression) as base technology enablers, DeepSpeed4Science will create a new set of AI system technologies tailored for accelerating scientific discoveries by addressing their unique complexity beyond the common technical approaches used for accelerating generic large language models (LLMs). In this paper, we showcase the early progress we made with DeepSpeed4Science in addressing two of the critical system challenges in structural biology research.

Xiaolong Ma, Xu Dong, Ashley Tarrant et al.

High-quality observations of hub-height winds are valuable but sparse in space and time. Simulations are widely available on regular grids but are generally biased and too coarse to inform wind-farm siting or to assess extreme-weather-related risks (e.g., gusts) at infrastructure scales. To fully utilize both data types for generating high-quality, high-resolution hub-height wind speeds (tens to ~100m above ground), this study introduces WindSR, a diffusion model with data assimilation for super-resolution downscaling of hub-height winds. WindSR integrates sparse observational data with simulation fields during downscaling using state-of-the-art diffusion models. A dynamic-radius blending method is introduced to merge observations with simulations, providing conditioning for the diffusion process. Terrain information is incorporated during both training and inference to account for its role as a key driver of winds. Evaluated against convolutional-neural-network and generative-adversarial-network baselines, WindSR outperforms them in both downscaling efficiency and accuracy. Our data assimilation reduces WindSR's model bias by approximately 20% relative to independent observations.