David A. Clifton

Chenyu You, Weicheng Dai, Yifei Min et al. · oxford

For medical image segmentation, contrastive learning is the dominant practice to improve the quality of visual representations by contrasting semantically similar and dissimilar pairs of samples. This is enabled by the observation that without accessing ground truth labels, negative examples with truly dissimilar anatomical features, if sampled, can significantly improve the performance. In reality, however, these samples may come from similar anatomical regions and the models may struggle to distinguish the minority tail-class samples, making the tail classes more prone to misclassification, both of which typically lead to model collapse. In this paper, we propose ARCO, a semi-supervised contrastive learning (CL) framework with stratified group theory for medical image segmentation. In particular, we first propose building ARCO through the concept of variance-reduced estimation and show that certain variance-reduction techniques are particularly beneficial in pixel/voxel-level segmentation tasks with extremely limited labels. Furthermore, we theoretically prove these sampling techniques are universal in variance reduction. Finally, we experimentally validate our approaches on eight benchmarks, i.e., five 2D/3D medical and three semantic segmentation datasets, with different label settings, and our methods consistently outperform state-of-the-art semi-supervised methods. Additionally, we augment the CL frameworks with these sampling techniques and demonstrate significant gains over previous methods. We believe our work is an important step towards semi-supervised medical image segmentation by quantifying the limitation of current self-supervision objectives for accomplishing such challenging safety-critical tasks.

Vinod Kumar Chauhan, Jiandong Zhou, Ping Lu et al. · oxford

Hypernetworks, or hypernets for short, are neural networks that generate weights for another neural network, known as the target network. They have emerged as a powerful deep learning technique that allows for greater flexibility, adaptability, dynamism, faster training, information sharing, and model compression. Hypernets have shown promising results in a variety of deep learning problems, including continual learning, causal inference, transfer learning, weight pruning, uncertainty quantification, zero-shot learning, natural language processing, and reinforcement learning. Despite their success across different problem settings, there is currently no comprehensive review available to inform researchers about the latest developments and to assist in utilizing hypernets. To fill this gap, we review the progress in hypernets. We present an illustrative example of training deep neural networks using hypernets and propose categorizing hypernets based on five design criteria: inputs, outputs, variability of inputs and outputs, and the architecture of hypernets. We also review applications of hypernets across different deep learning problem settings, followed by a discussion of general scenarios where hypernets can be effectively employed. Finally, we discuss the challenges and future directions that remain underexplored in the field of hypernets. We believe that hypernetworks have the potential to revolutionize the field of deep learning. They offer a new way to design and train neural networks, and they have the potential to improve the performance of deep learning models on a variety of tasks. Through this review, we aim to inspire further advancements in deep learning through hypernetworks.

Shreyank N Gowda, David A. Clifton

The Segment Anything Model (SAM) has achieved remarkable successes in the realm of natural image segmentation, but its deployment in the medical imaging sphere has encountered challenges. Specifically, the model struggles with medical images that feature low contrast, faint boundaries, intricate morphologies, and small-sized objects. To address these challenges and enhance SAM's performance in the medical domain, we introduce a comprehensive modification. Firstly, we incorporate a frozen Convolutional Neural Network (CNN) branch as an image encoder, which synergizes with SAM's original Vision Transformer (ViT) encoder through a novel variational attention fusion module. This integration bolsters the model's capability to capture local spatial information, which is often paramount in medical imagery. Moreover, to further optimize SAM for medical imaging, we introduce feature and position adapters within the ViT branch, refining the encoder's representations. We see that compared to current prompting strategies to fine-tune SAM for ultrasound medical segmentation, the use of text descriptions that serve as text prompts for SAM helps significantly improve the performance. Leveraging ChatGPT's natural language understanding capabilities, we generate prompts that offer contextual information and guidance to SAM, enabling it to better understand the nuances of ultrasound medical images and improve its segmentation accuracy. Our method, in its entirety, represents a significant stride towards making universal image segmentation models more adaptable and efficient in the medical domain.

Shreyank N Gowda, Boyan Gao, David A. Clifton

Utilizing large pre-trained models for specific tasks has yielded impressive results. However, fully fine-tuning these increasingly large models is becoming prohibitively resource-intensive. This has led to a focus on more parameter-efficient transfer learning, primarily within the same modality. But this approach has limitations, particularly in video understanding where suitable pre-trained models are less common. Addressing this, our study introduces a novel cross-modality transfer learning approach from images to videos, which we call parameter-efficient image-to-video transfer learning. We present the Facial-Emotion Adapter (FE-Adapter), designed for efficient fine-tuning in video tasks. This adapter allows pre-trained image models, which traditionally lack temporal processing capabilities, to analyze dynamic video content efficiently. Notably, it uses about 15 times fewer parameters than previous methods, while improving accuracy. Our experiments in video emotion recognition demonstrate that the FE-Adapter can match or even surpass existing fine-tuning and video emotion models in both performance and efficiency. This breakthrough highlights the potential for cross-modality approaches in enhancing the capabilities of AI models, particularly in fields like video emotion analysis where the demand for efficiency and accuracy is constantly rising.

Yining Hua, Hongbin Na, Zehan Li et al.

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains unclear. This scoping review aimed to assess the current generative applications of LLMs in mental health care, focusing on studies where these models were tested with human participants in real-world scenarios. A systematic search across APA PsycNet, Scopus, PubMed, and Web of Science identified 726 unique articles, of which 17 met the inclusion criteria. These studies encompassed applications such as clinical assistance, counseling, therapy, and emotional support. However, the evaluation methods were often non-standardized, with most studies relying on ad hoc scales that limit comparability and robustness. Privacy, safety, and fairness were also frequently underexplored. Moreover, reliance on proprietary models, such as OpenAI's GPT series, raises concerns about transparency and reproducibility. While LLMs show potential in expanding mental health care access, especially in underserved areas, the current evidence does not fully support their use as standalone interventions. More rigorous, standardized evaluations and ethical oversight are needed to ensure these tools can be safely and effectively integrated into clinical practice.

Boyan Gao, Bo Zhao, Shreyank N Gowda et al.

Dataset condensation aims to synthesize datasets with a few representative samples that can effectively represent the original datasets. This enables efficient training and produces models with performance close to those trained on the original sets. Most existing dataset condensation methods conduct dataset learning under the bilevel (inner- and outer-loop) based optimization. However, the preceding methods perform with limited dataset generalization due to the notoriously complicated loss landscape and expensive time-space complexity of the inner-loop unrolling of bilevel optimization. These issues deteriorate when the datasets are learned via matching the trajectories of networks trained on the real and synthetic datasets with a long horizon inner-loop. To address these issues, we introduce Sharpness-Aware Trajectory Matching (SATM), which enhances the generalization capability of learned synthetic datasets by optimising the sharpness of the loss landscape and objective simultaneously. Moreover, our approach is coupled with an efficient hypergradient approximation that is mathematically well-supported and straightforward to implement along with controllable computational overhead. Empirical evaluations of SATM demonstrate its effectiveness across various applications, including in-domain benchmarks and out-of-domain settings. Moreover, its easy-to-implement properties afford flexibility, allowing it to integrate with other advanced sharpness-aware minimizers. Our code will be released.

Sihao Liu, Yibo Yang, Xiaojie Li et al.

Online continual learning (OCL) seeks to learn new tasks from data streams that appear only once, while retaining knowledge of previously learned tasks. Most existing methods rely on replay, focusing on enhancing memory retention through regularization or distillation. However, they often overlook the adaptability of the model, limiting the ability to learn generalizable and discriminative features incrementally from online training data. To address this, we introduce a plug-and-play module, S6MOD, which can be integrated into most existing methods and directly improve adaptability. Specifically, S6MOD introduces an extra branch after the backbone, where a mixture of discretization selectively adjusts parameters in a selective state space model, enriching selective scan patterns such that the model can adaptively select the most sensitive discretization method for current dynamics. We further design a class-conditional routing algorithm for dynamic, uncertainty-based adjustment and implement a contrastive discretization loss to optimize it. Extensive experiments combining our module with various models demonstrate that S6MOD significantly enhances model adaptability, leading to substantial performance gains and achieving the state-of-the-art results.

Vinod Kumar Chauhan, Lei Clifton, Gaurav Nigam et al. · oxford

Estimating individualised treatment effect (ITE) -- that is the causal effect of a set of variables (also called exposures, treatments, actions, policies, or interventions), referred to as \textit{composite treatments}, on a set of outcome variables of interest, referred to as \textit{composite outcomes}, for a unit from observational data -- remains a fundamental problem in causal inference with applications across disciplines, such as healthcare, economics, education, social science, marketing, and computer science. Previous work in causal machine learning for ITE estimation is limited to simple settings, like single treatments and single outcomes. This hinders their use in complex real-world scenarios; for example, consider studying the effect of different ICU interventions, such as beta-blockers and statins for a patient admitted for heart surgery, on different outcomes of interest such as atrial fibrillation and in-hospital mortality. The limited research into composite treatments and outcomes is primarily due to data scarcity for all treatments and outcomes. To address the above challenges, we propose a novel and innovative hypernetwork-based approach, called \emph{H-Learner}, to solve ITE estimation under composite treatments and composite outcomes, which tackles the data scarcity issue by dynamically sharing information across treatments and outcomes. Our empirical analysis with binary and arbitrary composite treatments and outcomes demonstrates the effectiveness of the proposed approach compared to existing methods.