Zihao Lin

Binxu Li, Tiankai Yan, Yuanting Pan et al.

Multi-Modal Large Language Models (MLLMs), despite being successful, exhibit limited generality and often fall short when compared to specialized models. Recently, LLM-based agents have been developed to address these challenges by selecting appropriate specialized models as tools based on user inputs. However, such advancements have not been extensively explored within the medical domain. To bridge this gap, this paper introduces the first agent explicitly designed for the medical field, named \textbf{M}ulti-modal \textbf{Med}ical \textbf{Agent} (MMedAgent). We curate an instruction-tuning dataset comprising six medical tools solving seven tasks across five modalities, enabling the agent to choose the most suitable tools for a given task. Comprehensive experiments demonstrate that MMedAgent achieves superior performance across a variety of medical tasks compared to state-of-the-art open-source methods and even the closed-source model, GPT-4o. Furthermore, MMedAgent exhibits efficiency in updating and integrating new medical tools. Codes and models are all available.

Zihao Lin, Mohammad Beigi, Hongxuan Li et al.

Memory Editing (ME) has emerged as an efficient method to modify erroneous facts or inject new facts into Large Language Models (LLMs). Two mainstream ME methods exist: parameter-modifying ME and parameter-preserving ME (integrating extra modules while preserving original parameters). Regrettably, previous studies on ME evaluation have two critical limitations: (i) evaluating LLMs with single edit only, neglecting the need for continuous editing, and (ii) evaluations focusing solely on basic factual triples, overlooking broader LLM capabilities like logical reasoning and reading understanding. This study addresses these limitations with contributions threefold: (i) We explore how ME affects a wide range of fundamental capabilities of LLMs under sequential editing. Experimental results reveal an intriguing phenomenon: Most parameter-modifying ME consistently degrade performance across all tasks after a few sequential edits. In contrast, parameter-preserving ME effectively maintains LLMs' fundamental capabilities but struggles to accurately recall edited knowledge presented in a different format. (ii) We extend our evaluation to different editing settings, such as layers to edit, model size, instruction tuning, etc. Experimental findings indicate several strategies that can potentially mitigate the adverse effects of ME. (iii) We further explain why parameter-modifying ME damages LLMs from three dimensions: parameter changes after editing, language modeling capability, and the in-context learning capability. Our in-depth study advocates more careful use of ME in real-world scenarios.

Kaijie Chen, Zihao Lin, Zhiyang Xu et al.

Reasoning is a fundamental capability often required in real-world text-to-image (T2I) generation, e.g., generating ``a bitten apple that has been left in the air for more than a week`` necessitates understanding temporal decay and commonsense concepts. While recent T2I models have made impressive progress in producing photorealistic images, their reasoning capability remains underdeveloped and insufficiently evaluated. To bridge this gap, we introduce R2I-Bench, a comprehensive benchmark specifically designed to rigorously assess reasoning-driven T2I generation. R2I-Bench comprises meticulously curated data instances, spanning core reasoning categories, including commonsense, mathematical, logical, compositional, numerical, causal, and concept mixing. To facilitate fine-grained evaluation, we design R2IScore, a QA-style metric based on instance-specific, reasoning-oriented evaluation questions that assess three critical dimensions: text-image alignment, reasoning accuracy, and image quality. Extensive experiments with 16 representative T2I models, including a strong pipeline-based framework that decouples reasoning and generation using the state-of-the-art language and image generation models, demonstrate consistently limited reasoning performance, highlighting the need for more robust, reasoning-aware architectures in the next generation of T2I systems. Project Page: https://r2i-bench.github.io

Yuxiang Zhang, Jing Chen, Junjie Wang et al.

Tool-augmented large language models (LLMs) are rapidly being integrated into real-world applications. Due to the lack of benchmarks, the community has yet to fully understand the hallucination issues within these models. To address this challenge, we introduce a comprehensive diagnostic benchmark, ToolBH. Specifically, we assess the LLM's hallucinations through two perspectives: depth and breadth. In terms of depth, we propose a multi-level diagnostic process, including (1) solvability detection, (2) solution planning, and (3) missing-tool analysis. For breadth, we consider three scenarios based on the characteristics of the toolset: missing necessary tools, potential tools, and limited functionality tools. Furthermore, we developed seven tasks and collected 700 evaluation samples through multiple rounds of manual annotation. The results show the significant challenges presented by the ToolBH benchmark. The current advanced models Gemini-1.5-Pro and GPT-4o only achieve total scores of 45.3 and 37.0, respectively, on a scale of 100. In this benchmark, larger model parameters do not guarantee better performance; the training data and response strategies also play crucial roles in tool-enhanced LLM scenarios. Our diagnostic analysis indicates that the primary reason for model errors lies in assessing task solvability. Additionally, open-weight models suffer from performance drops with verbose replies, whereas proprietary models excel with longer reasoning.

Minqian Liu, Zhiyang Xu, Zihao Lin et al.

Interleaved text-and-image generation has been an intriguing research direction, where the models are required to generate both images and text pieces in an arbitrary order. Despite the emerging advancements in interleaved generation, the progress in its evaluation still significantly lags behind. Existing evaluation benchmarks do not support arbitrarily interleaved images and text for both inputs and outputs, and they only cover a limited number of domains and use cases. Also, current works predominantly use similarity-based metrics which fall short in assessing the quality in open-ended scenarios. To this end, we introduce InterleavedBench, the first benchmark carefully curated for the evaluation of interleaved text-and-image generation. InterleavedBench features a rich array of tasks to cover diverse real-world use cases. In addition, we present InterleavedEval, a strong reference-free metric powered by GPT-4o to deliver accurate and explainable evaluation. We carefully define five essential evaluation aspects for InterleavedEval, including text quality, perceptual quality, image coherence, text-image coherence, and helpfulness, to ensure a comprehensive and fine-grained assessment. Through extensive experiments and rigorous human evaluation, we show that our benchmark and metric can effectively evaluate the existing models with a strong correlation with human judgments surpassing previous reference-based metrics. We also provide substantial findings and insights to foster future research in interleaved generation and its evaluation.

Yixin Wang, Yang Zhang, Yang Liu et al.

Accurate segmentation of brain tumors from magnetic resonance imaging (MRI) is clinically relevant in diagnoses, prognoses and surgery treatment, which requires multiple modalities to provide complementary morphological and physiopathologic information. However, missing modality commonly occurs due to image corruption, artifacts, different acquisition protocols or allergies to certain contrast agents in clinical practice. Though existing efforts demonstrate the possibility of a unified model for all missing situations, most of them perform poorly when more than one modality is missing. In this paper, we propose a novel Adversarial Co-training Network (ACN) to solve this issue, in which a series of independent yet related models are trained dedicated to each missing situation with significantly better results. Specifically, ACN adopts a novel co-training network, which enables a coupled learning process for both full modality and missing modality to supplement each other's domain and feature representations, and more importantly, to recover the `missing' information of absent modalities. Then, two unsupervised modules, i.e., entropy and knowledge adversarial learning modules are proposed to minimize the domain gap while enhancing prediction reliability and encouraging the alignment of latent representations, respectively. We also adapt modality-mutual information knowledge transfer learning to ACN to retain the rich mutual information among modalities. Extensive experiments on BraTS2018 dataset show that our proposed method significantly outperforms all state-of-the-art methods under any missing situation.