Lang Cao

Pengcheng Jiang, Lang Cao, Ruike Zhu et al. · amazon-science

Large language models (LLMs) have achieved impressive performance on knowledge-intensive tasks, yet they often struggle with multi-step reasoning due to the unstructured nature of retrieved context. While retrieval-augmented generation (RAG) methods provide external information, the lack of explicit organization among retrieved passages limits their effectiveness, leading to brittle reasoning pathways. Recent interpretability studies highlighting the importance of structured intermediate reasoning further align with this perspective. We propose Retrieval-And-Structuring (RAS), a framework that dynamically constructs query-specific knowledge graphs through iterative retrieval and structured knowledge building. RAS interleaves targeted retrieval planning with incremental graph construction, enabling models to assemble and reason over evolving knowledge structures tailored to each query. On seven knowledge-intensive benchmarks, RAS consistently outperforms strong baselines, achieving up to 6.4% and 7.0% gains with open-source and proprietary LLMs, respectively. Our results demonstrate that dynamic, query-specific knowledge structuring offers a robust path to improving reasoning accuracy and robustness in language model generation. Our data and code can be found at https://github.com/pat-jj/RAS.

Lang Cao

Argument mining is to analyze argument structure and extract important argument information from unstructured text. An argument mining system can help people automatically gain causal and logical information behind the text. As argumentative corpus gradually increases, like more people begin to argue and debate on social media, argument mining from them is becoming increasingly critical. However, argument mining is still a big challenge in natural language tasks due to its difficulty, and relative techniques are not mature. For example, research on non-tree argument mining needs to be done more. Most works just focus on extracting tree structure argument information. Moreover, current methods cannot accurately describe and capture argument relations and do not predict their types. In this paper, we propose a novel neural model called AutoAM to solve these problems. We first introduce the argument component attention mechanism in our model. It can capture the relevant information between argument components, so our model can better perform argument mining. Our model is a universal end-to-end framework, which can analyze argument structure without constraints like tree structure and complete three subtasks of argument mining in one model. The experiment results show that our model outperforms the existing works on several metrics in two public datasets.

Lang Cao

A significant application of Large Language Models (LLMs), like ChatGPT, is their deployment as chat agents, which respond to human inquiries across a variety of domains. While current LLMs proficiently answer general questions, they often fall short in complex diagnostic scenarios such as legal, medical, or other specialized consultations. These scenarios typically require Task-Oriented Dialogue (TOD), where an AI chat agent must proactively pose questions and guide users toward specific goals or task completion. Previous fine-tuning models have underperformed in TOD and the full potential of conversational capability in current LLMs has not yet been fully explored. In this paper, we introduce DiagGPT (Dialogue in Diagnosis GPT), an innovative approach that extends LLMs to more TOD scenarios. In addition to guiding users to complete tasks, DiagGPT can effectively manage the status of all topics throughout the dialogue development. This feature enhances user experience and offers a more flexible interaction in TOD. Our experiments demonstrate that DiagGPT exhibits outstanding performance in conducting TOD with users, showing its potential for practical applications in various fields.

Lang Cao, Hanbing Liu

Tables serve as a fundamental format for representing structured relational data. While current language models (LMs) excel at many text-based tasks, they still face challenges in table understanding due to the complex characteristics of tabular data, such as their structured nature. In this paper, we aim to enhance LMs for improved table understanding. We identify four key challenges: 1) difficulty in locating target data, 2) deficiency in table semantics, 3) numerical inaccuracies in textual reasoning, and 4) semantic inflexibility in symbolic reasoning. To address these issues, we propose TableMaster, a recipe and comprehensive framework that integrates multiple solutions to overcome these obstacles. TableMaster first extracts relevant table content and verbalizes it with enriched semantic context. Additionally, we introduce adaptive reasoning, a flexible approach that dynamically adjusts between textual and symbolic reasoning, tailoring the reasoning process to each query. Extensive analyses and experiments demonstrate our findings and the effectiveness of TableMaster. On the WikiTQ dataset, TableMaster achieves an accuracy of 78.13% using GPT-4o-mini, surpassing existing baselines.

Zifeng Wang, Lang Cao, Qiao Jin et al.

Systematic literature review is essential for evidence-based medicine, requiring comprehensive analysis of clinical trial publications. However, the application of artificial intelligence (AI) models for medical literature mining has been limited by insufficient training and evaluation across broad therapeutic areas and diverse tasks. Here, we present LEADS, an AI foundation model for study search, screening, and data extraction from medical literature. The model is trained on 633,759 instruction data points in LEADSInstruct, curated from 21,335 systematic reviews, 453,625 clinical trial publications, and 27,015 clinical trial registries. We showed that LEADS demonstrates consistent improvements over four cutting-edge generic large language models (LLMs) on six tasks. Furthermore, LEADS enhances expert workflows by providing supportive references following expert requests, streamlining processes while maintaining high-quality results. A study with 16 clinicians and medical researchers from 14 different institutions revealed that experts collaborating with LEADS achieved a recall of 0.81 compared to 0.77 experts working alone in study selection, with a time savings of 22.6%. In data extraction tasks, experts using LEADS achieved an accuracy of 0.85 versus 0.80 without using LEADS, alongside a 26.9% time savings. These findings highlight the potential of specialized medical literature foundation models to outperform generic models, delivering significant quality and efficiency benefits when integrated into expert workflows for medical literature mining.

Yihao Liu, Shuocheng Li, Lang Cao et al.

Large language models are increasingly used for complex reasoning tasks where high-quality offline data such as expert-annotated solutions and distilled reasoning traces are often available. However, in environments with sparse rewards, reinforcement learning struggles to sample successful trajectories, leading to inefficient learning. At the same time, these offline trajectories that represent correct reasoning paths are not utilized by standard on-policy reinforcement learning methods. We introduce SuperRL, a unified training framework that adaptively alternates between RL and SFT. Whenever every rollout for a given instance receives zero reward, indicating the absence of a learning signal, SuperRL falls back to SFT on the curated offline data. Extensive experiments across diverse reasoning benchmarks show that SuperRL surpasses vanilla RL by delivering higher sample efficiency, stronger generalization, and improved robustness under sparse rewards.

Lang Cao, Jimeng Sun, Adam Cross

Rare diseases affect millions worldwide but often face limited research focus due to their low prevalence. This results in prolonged diagnoses and a lack of approved therapies. Recent advancements in Large Language Models (LLMs) have shown promise in automating the extraction of medical information, offering potential to improve medical diagnosis and management. However, most LLMs lack professional medical knowledge, especially concerning rare diseases, and struggle to handle the latest rare disease information. They also cannot effectively manage rare disease data and are not directly suitable for diagnosis and management tasks. Our objective is to create an end-to-end system called AutoRD, which automates the extraction of information from medical texts about rare diseases, focusing on entities and their relations. AutoRD integrates up-to-date structured knowledge and demonstrates superior performance in rare disease extraction tasks. We conduct various experiments to evaluate AutoRD's performance, aiming to surpass common LLMs and traditional methods.

Hanbing Liu, Lang Cao, Yuanyi Ren et al.

Large language models have demonstrated impressive reasoning capabilities, yet they often suffer from inefficiencies due to unnecessarily verbose or redundant outputs. While many works have explored reinforcement learning (RL) to enhance reasoning abilities, most primarily focus on improving accuracy, with limited attention to reasoning efficiency. Some existing approaches introduce direct length-based rewards to encourage brevity, but this often leads to noticeable drops in accuracy. In this paper, we propose Bingo, an RL framework that advances length-based reward design to boost efficient reasoning. Bingo incorporates two key mechanisms: a significance-aware length reward, which gradually guides the model to reduce only insignificant tokens, and a dynamic length reward, which initially encourages elaborate reasoning for hard questions but decays over time to improve overall efficiency. Experiments across multiple reasoning benchmarks show that Bingo improves both accuracy and efficiency. It outperforms the vanilla reward and several other length-based reward baselines in RL, achieving a favorable trade-off between accuracy and efficiency. These results underscore the potential of training LLMs explicitly for efficient reasoning.

Deyin Yi, Yihao Liu, Lang Cao et al.

Tabular data analysis is crucial in many scenarios, yet efficiently identifying the most relevant data analysis queries and results for a new table remains a significant challenge. The complexity of tabular data, diverse analytical operations, and the demand for high-quality analysis make the process tedious. To address these challenges, we aim to recommend query-code-result triplets tailored for new tables in tabular data analysis workflows. In this paper, we present TablePilot, a pioneering tabular data analysis framework leveraging large language models to autonomously generate comprehensive and superior analytical results without relying on user profiles or prior interactions. The framework incorporates key designs in analysis preparation and analysis optimization to enhance accuracy. Additionally, we propose Rec-Align, a novel method to further improve recommendation quality and better align with human preferences. Experiments on DART, a dataset specifically designed for comprehensive tabular data analysis recommendation, demonstrate the effectiveness of our framework. Based on GPT-4o, the tuned TablePilot achieves 77.0% top-5 recommendation recall. Human evaluations further highlight its effectiveness in optimizing tabular data analysis workflows.

Lang Cao, Jingxian Xu, Hanbing Liu et al.

Tables are a fundamental structure for organizing and analyzing data, making effective table understanding a critical capability for intelligent systems. While large language models (LMs) demonstrate strong general reasoning abilities, they continue to struggle with accurate numerical or symbolic reasoning over tabular data, especially in complex scenarios. Spreadsheet formulas provide a powerful and expressive medium for representing executable symbolic operations, encoding rich reasoning patterns that remain largely underutilized. In this paper, we propose Formula Tuning (Fortune), a reinforcement learning (RL) framework that trains LMs to generate executable spreadsheet formulas for question answering over general tabular data. Formula Tuning reduces the reliance on supervised formula annotations by using binary answer correctness as a reward signal, guiding the model to learn formula derivation through reasoning. We provide a theoretical analysis of its advantages and demonstrate its effectiveness through extensive experiments on seven table reasoning benchmarks. Formula Tuning substantially enhances LM performance, particularly on multi-step numerical and symbolic reasoning tasks, enabling a 7B model to outperform OpenAI o1 on table understanding. This highlights the potential of formula-driven RL to advance symbolic table reasoning in LMs.

Zifeng Wang, Lang Cao, Benjamin Danek et al.

Synthesizing clinical evidence largely relies on systematic reviews of clinical trials and retrospective analyses from medical literature. However, the rapid expansion of publications presents challenges in efficiently identifying, summarizing, and updating clinical evidence. Here, we introduce TrialMind, a generative artificial intelligence (AI) pipeline for facilitating human-AI collaboration in three crucial tasks for evidence synthesis: study search, screening, and data extraction. To assess its performance, we chose published systematic reviews to build the benchmark dataset, named TrialReviewBench, which contains 100 systematic reviews and the associated 2,220 clinical studies. Our results show that TrialMind excels across all three tasks. In study search, it generates diverse and comprehensive search queries to achieve high recall rates (Ours 0.711-0.834 v.s. Human baseline 0.138-0.232). For study screening, TrialMind surpasses traditional embedding-based methods by 30% to 160%. In data extraction, it outperforms a GPT-4 baseline by 29.6% to 61.5%. We further conducted user studies to confirm its practical utility. Compared to manual efforts, human-AI collaboration using TrialMind yielded a 71.4% recall lift and 44.2% time savings in study screening and a 23.5% accuracy lift and 63.4% time savings in data extraction. Additionally, when comparing synthesized clinical evidence presented in forest plots, medical experts favored TrialMind's outputs over GPT-4's outputs in 62.5% to 100% of cases. These findings show the promise of LLM-based approaches like TrialMind to accelerate clinical evidence synthesis via streamlining study search, screening, and data extraction from medical literature, with exceptional performance improvement when working with human experts.