Siyu Yan

Xingjian Wu, Junkai Lu, Siyu Yan et al.

Recent advances in Large Language Models (LLMs) have catalyzed the development of multi-agent systems (MAS) for complex reasoning tasks. However, existing MAS typically rely on pre-defined or pre-compiled communication topologies, which limits their flexibility and adaptability to dynamic task requirements. In this work, we propose Differentiable Mixture-of-Agents (DMoA), a self-evolving multi-agent framework that enables elastic and adaptive agent collaboration during inference. Instead of statically constructing workflows, DMoA dynamically routes and activates agents at each reasoning step, allowing the system to implicitly simulate diverse communication topologies and adapt to evolving demands. To achieve this, we design a differentiable, context-aware routing mechanism that leverages recurrent structures to incorporate historical and contextual information, producing sparse agent activations in a step-wise manner. Furthermore, we introduce predictive entropy as self-supervised signals to optimize the routing process, enabling efficient test-time adaptation without external annotations. Extensive experiments across 9 benchmarks demonstrate that DMoA achieves state-of-the-art performance while exhibiting strong efficiency, robustness, and ensembling capabilities.

Zhe Sun, Runzhi Li, Jing Wang et al.

Background: Accurate short-term readmission prediction of ICU patients is significant in improving the efficiency of resource assignment by assisting physicians in making discharge decisions. Clinically, both individual static static and multivariate temporal data collected from ICU monitors play critical roles in short-term readmission prediction. Informative static and multivariate temporal feature representation capturing and fusion present challenges for accurate readmission prediction. Methods:We propose a novel static and multivariate-temporal attentive fusion transformer (SMTAFormer) to predict short-term readmission of ICU patients by fully leveraging the potential of demographic and dynamic temporal data. In SMTAFormer, we first apply an MLP network and a temporal transformer network to learn useful static and temporal feature representations, respectively. Then, the well-designed static and multivariate temporal feature fusion module is applied to fuse static and temporal feature representations by modeling intra-correlation among multivariate temporal features and constructing inter-correlation between static and multivariate temporal features. Results: We construct a readmission risk assessment (RRA) dataset based on the MIMIC-III dataset. The extensive experiments show that SMTAFormer outperforms advanced methods, in which the accuracy of our proposed method is up to 86.6%, and the area under the receiver operating characteristic curve (AUC) is up to 0.717. Conclusion: Our proposed SMTAFormer can efficiently capture and fuse static and multivariate temporal feature representations. The results show that SMTAFormer significantly improves the short-term readmission prediction performance of ICU patients through comparisons to strong baselines.

Siyu Yan, Long Zeng, Xuecheng Wu et al.

As large language models~(LLMs) become widely adopted, ensuring their alignment with human values is crucial to prevent jailbreaks where adversaries manipulate models to produce harmful content. While most defenses target single-turn attacks, real-world usage often involves multi-turn dialogues, exposing models to attacks that exploit conversational context to bypass safety measures. We introduce MUSE, a comprehensive framework tackling multi-turn jailbreaks from both attack and defense angles. For attacks, we propose MUSE-A, a method that uses frame semantics and heuristic tree search to explore diverse semantic trajectories. For defense, we present MUSE-D, a fine-grained safety alignment approach that intervenes early in dialogues to reduce vulnerabilities. Extensive experiments on various models show that MUSE effectively identifies and mitigates multi-turn vulnerabilities. Code is available at \href{https://github.com/yansiyu02/MUSE}{https://github.com/yansiyu02/MUSE}.

Yu Xia, Jingru Fan, Weize Chen et al. · tsinghua

Existing LLM-based agents have achieved strong performance on held-in tasks, but their generalizability to unseen tasks remains poor. Hence, some recent work focus on fine-tuning the policy model with more diverse tasks to improve the generalizability. In this work, we find that finetuning a reward model to guide the policy model is more robust than directly finetuning the policy model. Based on this finding, we propose AgentRM, a generalizable reward model, to guide the policy model for effective test-time search. We comprehensively investigate three approaches to construct the reward model, including explicit reward modeling, implicit reward modeling and LLM-as-a-judge. We then use AgentRM to guide the answer generation with Best-of-N sampling and step-level beam search. On four types of nine agent tasks, AgentRM enhances the base policy model by $8.8$ points on average, surpassing the top general agent by $4.0$. Moreover, it demonstrates weak-to-strong generalization, yielding greater improvement of $12.6$ on LLaMA-3-70B policy model. As for the specializability, AgentRM can also boost a finetuned policy model and outperform the top specialized agent by $11.4$ on three held-in tasks. Further analysis verifies its effectiveness in test-time scaling. Codes will be released to facilitate the research in this area.

Kedi Chen, Dezhao Ruan, Yuhao Dan et al.

Reasoning is an important task for large language models (LLMs). Among all the reasoning paradigms, inductive reasoning is one of the fundamental types, which is characterized by its particular-to-general thinking process and the non-uniqueness of its answers. The inductive mode is crucial for knowledge generalization and aligns better with human cognition, so it is a fundamental mode of learning, hence attracting increasing interest. Despite the importance of inductive reasoning, there is no systematic summary of it. Therefore, this paper presents the first comprehensive survey of inductive reasoning for LLMs. First, methods for improving inductive reasoning are categorized into three main areas: post-training, test-time scaling, and data augmentation. Then, current benchmarks of inductive reasoning are summarized, and a unified sandbox-based evaluation approach with the observation coverage metric is derived. Finally, we offer some analyses regarding the source of inductive ability and how simple model architectures and data help with inductive tasks, providing a solid foundation for future research.

Zijian Zhang, Xuecheng Wu, Danlei Huang et al.

Driven by the rapid progress in vision-language models (VLMs), the responsible behavior of large-scale multimodal models has become a prominent research area, particularly focusing on hallucination detection and factuality checking. In this paper, we present the solution for the two tracks of Responsible AI challenge. Inspirations from the general domain demonstrate that a smaller distilled VLM can often outperform a larger VLM that is directly tuned on downstream tasks, while achieving higher efficiency. We thus jointly tackle two tasks from the perspective of knowledge distillation and propose a progressive hybrid knowledge distillation framework termed HKD4VLM. Specifically, the overall framework can be decomposed into Pyramid-like Progressive Online Distillation and Ternary-Coupled Refinement Distillation, hierarchically moving from coarse-grained knowledge alignment to fine-grained refinement. Besides, we further introduce the mapping shift-enhanced inference and diverse augmentation strategies to enhance model performance and robustness. Extensive experimental results demonstrate the effectiveness of our HKD4VLM. Ablation studies provide insights into the critical design choices driving performance gains.

Zhihao Shuai, Boyan Li, Siyu Yan et al.

Although data visualization is powerful for revealing patterns and communicating insights, creating effective visualizations requires familiarity with authoring tools and often disrupts the analysis flow. While large language models show promise for automatically converting analysis intent into visualizations, existing methods function as black boxes without transparent reasoning processes, which prevents users from understanding design rationales and refining suboptimal outputs. To bridge this gap, we propose integrating Chain-of-Thought (CoT) reasoning into the Natural Language to Visualization (NL2VIS) pipeline. First, we design a comprehensive CoT reasoning process for NL2VIS and develop an automatic pipeline to equip existing datasets with structured reasoning steps. Second, we introduce nvBench-CoT, a specialized dataset capturing detailed step-by-step reasoning from ambiguous natural language descriptions to finalized visualizations, which enables state-of-the-art performance when used for model fine-tuning. Third, we develop DeepVIS, an interactive visual interface that tightly integrates with the CoT reasoning process, allowing users to inspect reasoning steps, identify errors, and make targeted adjustments to improve visualization outcomes. Quantitative benchmark evaluations, two use cases, and a user study collectively demonstrate that our CoT framework effectively enhances NL2VIS quality while providing insightful reasoning steps to users.

Zerui Yang, Yuwei Wan, Siyu Yan et al.

Recent advances in large language models have demonstrated considerable potential in scientific domains such as drug repositioning. However, their effectiveness remains constrained when reasoning extends beyond the knowledge acquired during pretraining. Conventional approaches, such as fine-tuning or retrieval-augmented generation, face limitations in either imposing high computational overhead or failing to fully exploit structured scientific data. To overcome these challenges, we propose DrugMCTS, a novel framework that synergistically integrates RAG, multi-agent collaboration, and Monte Carlo Tree Search for drug repositioning. The framework employs five specialized agents tasked with retrieving and analyzing molecular and protein information, thereby enabling structured and iterative reasoning. Extensive experiments on the DrugBank and KIBA datasets demonstrate that DrugMCTS achieves substantially higher recall and robustness compared to both general-purpose LLMs and deep learning baselines. Our results highlight the importance of structured reasoning, agent-based collaboration, and feedback-driven search mechanisms in advancing LLM applications for drug repositioning.

Danni Feng, Runzhi Li, Jing Wang et al.

Joint entity-relation extraction is a critical task in transforming unstructured or semi-structured text into triplets, facilitating the construction of large-scale knowledge graphs, and supporting various downstream applications. Despite its importance, research on Chinese text, particularly with complex semantics in specialized domains like medicine, remains limited. To address this gap, we introduce the CH-DDI, a Chinese drug-drug interactions dataset designed to capture the intricacies of medical text. Leveraging the strengths of attention mechanisms in capturing long-range dependencies, we propose the SEA module, which enhances the extraction of complex contextual semantic information, thereby improving entity recognition and relation extraction. Additionally, to address the inefficiencies of existing methods in facilitating information exchange between entity recognition and relation extraction, we present an interactive fusion representation module. This module employs Cross Attention for bidirectional information exchange between the tasks and further refines feature extraction through BiLSTM. Experimental results on both our CH-DDI dataset and public CoNLL04 dataset demonstrate that our model exhibits strong generalization capabilities. On the CH-DDI dataset, our model achieves an F1-score of 96.73% for entity recognition and 78.43% for relation extraction. On the CoNLL04 dataset, it attains an entity recognition precision of 89.54% and a relation extraction accuracy of 71.64%.

Chang Wang, Siyu Yan, Depeng Yuan et al.

The generation of ad headlines plays a vital role in modern advertising, where both quality and diversity are essential to engage a broad range of audience segments. Current approaches primarily optimize language models for headline quality or click-through rates (CTR), often overlooking the need for diversity and resulting in homogeneous outputs. To address this limitation, we propose DIVER, a novel framework based on large language models (LLMs) that are jointly optimized for both diversity and quality. We first design a semantic- and stylistic-aware data generation pipeline that automatically produces high-quality training pairs with ad content and multiple diverse headlines. To achieve the goal of generating high-quality and diversified ad headlines within a single forward pass, we propose a multi-stage multi-objective optimization framework with supervised fine-tuning (SFT) and reinforcement learning (RL). Experiments on real-world industrial datasets demonstrate that DIVER effectively balances quality and diversity. Deployed on a large-scale content-sharing platform serving hundreds of millions of users, our framework improves advertiser value (ADVV) and CTR by 4.0% and 1.4%.