Guoxin Kang

Chenxi Wang, Lei Wang, Wanling Gao et al.

In a computer system, multiple indispensable components-such as the CPU, memory, and others-work together with other essential components to produce an overall effect, which can only be measured on an independently running system. Since the system operates as an integrated whole, isolating the effect of individual components is challenging. Accurately attributing the system's overall effect to its specific component is crucial for both computer design and evaluation. Taking CPU evaluation as a benchmark, our experiments reveal that the general-purpose rigorous methodologies, like DoE, RCTs, can not address this issue efficiently; A single-purpose empirical methodology, SPEC CPU2017, which is the industry-standard CPU benchmark, only reports the overall effect. Even more concerningly, for the identical CPU, the undefined configurations of other indispensable components introduce uncontrolled variability, with the SPEC scores fluctuating from 12.16\% to 436.80\%. We propose a rigorous methodology that can attribute the overall effect to its specific component, which can be utilized in computer component evaluations and design, as well as in other areas. Through theoretical analysis and pioneering controlled experiments, we systematically compare our methodology against three established methodologies: SPEC CPU2017, DoE, and RCTs. The results show our methodology can achieve its goal in a cost-efficient way, while others exhibit inherent limitations.

Yunyou Huang, Nana Wang, Suqin Tang et al.

This paper quantitatively reveals the state-of-the-art and state-of-the-practice AI systems only achieve acceptable performance on the stringent conditions that all categories of subjects are known, which we call closed clinical settings, but fail to work in real-world clinical settings. Compared to the diagnosis task in the closed setting, real-world clinical settings pose severe challenges, and we must treat them differently. We build a clinical AI benchmark named Clinical AIBench to set up real-world clinical settings to facilitate researches. We propose an open, dynamic machine learning framework and develop an AI system named OpenClinicalAI to diagnose diseases in real-world clinical settings. The first versions of Clinical AIBench and OpenClinicalAI target Alzheimer's disease. In the real-world clinical setting, OpenClinicalAI significantly outperforms the state-of-the-art AI system. In addition, OpenClinicalAI develops personalized diagnosis strategies to avoid unnecessary testing and seamlessly collaborates with clinicians. It is promising to be embedded in the current medical systems to improve medical services.