Chun-An Chou

Haidong Gu, Nathan Gaw, Yinan Wang et al.

Discovering human cognitive and emotional states using multi-modal physiological signals draws attention across various research applications. Physiological responses of the human body are influenced by human cognition and commonly used to analyze cognitive states. From a network science perspective, the interactions of these heterogeneous physiological modalities in a graph structure may provide insightful information to support prediction of cognitive states. However, there is no clue to derive exact connectivity between heterogeneous modalities and there exists a hierarchical structure of sub-modalities. Existing graph neural networks are designed to learn on non-hierarchical homogeneous graphs with pre-defined graph structures; they failed to learn from hierarchical, multi-modal physiological data without a pre-defined graph structure. To this end, we propose a hierarchical heterogeneous graph generative network (H2G2-Net) that automatically learns a graph structure without domain knowledge, as well as a powerful representation on the hierarchical heterogeneous graph in an end-to-end fashion. We validate the proposed method on the CogPilot dataset that consists of multi-modal physiological signals. Extensive experiments demonstrate that our proposed method outperforms the state-of-the-art GNNs by 5%-20% in prediction accuracy.

Yilin Yin, Chun-An Chou

Respiratory failure is the one of major causes of death in critical care unit. During the outbreak of COVID-19, critical care units experienced an extreme shortage of mechanical ventilation because of respiratory failure related syndromes. To help this, the early mortality risk prediction in patients who suffer respiratory failure can provide timely support for clinical treatment and resource management. In the study, we propose a dynamic modeling approach for early mortality risk prediction of the respiratory failure patients based on the first 24 hours ICU physiological data. Our proposed model is validated on the eICU collaborate database. We achieved a high AUROC performance (80-83%) and significantly improved AUCPR 4% on Day 5 since ICU admission, compared to the state-of-art prediction models. In addition, we illustrated that the survival curve includes the time-varying information for the early ICU admission survival analysis.

Miaolin Fan, Chun-An Chou, Sheng-Che Yen et al.

Characterizing the dynamic interactive patterns of complex systems helps gain in-depth understanding of how components interrelate with each other while performing certain functions as a whole. In this study, we present a novel multimodal data fusion approach to construct a complex network, which models the interactions of biological subsystems in the human body under emotional states through physiological responses. Joint recurrence plot and temporal network metrics are employed to integrate the multimodal information at the signal level. A benchmark public dataset of is used for evaluating our model.

Yu Yin, Mohsen Nabian, Miolin Fan et al.

In this paper, we present a multimodal approach to simultaneously analyze facial movements and several peripheral physiological signals to decode individualized affective experiences under positive and negative emotional contexts, while considering their personalized resting dynamics. We propose a person-specific recurrence network to quantify the dynamics present in the person's facial movements and physiological data. Facial movement is represented using a robust head vs. 3D face landmark localization and tracking approach, and physiological data are processed by extracting known attributes related to the underlying affective experience. The dynamical coupling between different input modalities is then assessed through the extraction of several complex recurrent network metrics. Inference models are then trained using these metrics as features to predict individual's affective experience in a given context, after their resting dynamics are excluded from their response. We validated our approach using a multimodal dataset consists of (i) facial videos and (ii) several peripheral physiological signals, synchronously recorded from 12 participants while watching 4 emotion-eliciting video-based stimuli. The affective experience prediction results signified that our multimodal fusion method improves the prediction accuracy up to 19% when compared to the prediction using only one or a subset of the input modalities. Furthermore, we gained prediction improvement for affective experience by considering the effect of individualized resting dynamics.