17.4AIAug 20, 2025Code
aiXiv: A Next-Generation Open Access Ecosystem for Scientific Discovery Generated by AI ScientistsPengsong Zhang, Xiang Hu, Guowei Huang et al.
Recent advances in large language models (LLMs) have enabled AI agents to autonomously generate scientific proposals, conduct experiments, author papers, and perform peer reviews. Yet this flood of AI-generated research content collides with a fragmented and largely closed publication ecosystem. Traditional journals and conferences rely on human peer review, making them difficult to scale and often reluctant to accept AI-generated research content; existing preprint servers (e.g. arXiv) lack rigorous quality-control mechanisms. Consequently, a significant amount of high-quality AI-generated research lacks appropriate venues for dissemination, hindering its potential to advance scientific progress. To address these challenges, we introduce aiXiv, a next-generation open-access platform for human and AI scientists. Its multi-agent architecture allows research proposals and papers to be submitted, reviewed, and iteratively refined by both human and AI scientists. It also provides API and MCP interfaces that enable seamless integration of heterogeneous human and AI scientists, creating a scalable and extensible ecosystem for autonomous scientific discovery. Through extensive experiments, we demonstrate that aiXiv is a reliable and robust platform that significantly enhances the quality of AI-generated research proposals and papers after iterative revising and reviewing on aiXiv. Our work lays the groundwork for a next-generation open-access ecosystem for AI scientists, accelerating the publication and dissemination of high-quality AI-generated research content. Code is available at https://github.com/aixiv-org. Website is available at https://forms.gle/DxQgCtXFsJ4paMtn8.
8.3CLMar 4, 2025
From Metaphor to Mechanism: How LLMs Decode Traditional Chinese Medicine Symbolic Language for Modern Clinical RelevanceJiacheng Tang, Nankai Wu, Fan Gao et al.
Metaphorical expressions are abundant in Traditional Chinese Medicine (TCM), conveying complex disease mechanisms and holistic health concepts through culturally rich and often abstract terminology. Bridging these metaphors to anatomically driven Western medical (WM) concepts poses significant challenges for both automated language processing and real-world clinical practice. To address this gap, we propose a novel multi-agent and chain-of-thought (CoT) framework designed to interpret TCM metaphors accurately and map them to WM pathophysiology. Specifically, our approach combines domain-specialized agents (TCM Expert, WM Expert) with a Coordinator Agent, leveraging stepwise chain-of-thought prompts to ensure transparent reasoning and conflict resolution. We detail a methodology for building a metaphor-rich TCM dataset, discuss strategies for effectively integrating multi-agent collaboration and CoT reasoning, and articulate the theoretical underpinnings that guide metaphor interpretation across distinct medical paradigms. We present a comprehensive system design and highlight both the potential benefits and limitations of our approach, while leaving placeholders for future experimental validation. Our work aims to support clinical decision-making, cross-system educational initiatives, and integrated healthcare research, ultimately offering a robust scaffold for reconciling TCM's symbolic language with the mechanistic focus of Western medicine.
4.9CLAug 3, 2025
AGENTICT$^2$S:Robust Text-to-SPARQL via Agentic Collaborative Reasoning over Heterogeneous Knowledge Graphs for the Circular EconomyYang Zhao, Chengxiao Dai, Wei Zhuo et al.
Question answering over heterogeneous knowledge graphs (KGQA) involves reasoning across diverse schemas, incomplete alignments, and distributed data sources. Existing text-to-SPARQL approaches rely on large-scale domain-specific fine-tuning or operate within single-graph settings, limiting their generalizability in low-resource domains and their ability to handle queries spanning multiple graphs. These challenges are particularly relevant in domains such as the circular economy, where information about classifications, processes, and emissions is distributed across independently curated knowledge graphs (KGs). We present AgenticT$^2$S, a modular framework that decomposes KGQA into subtasks managed by specialized agents responsible for retrieval, query generation, and verification. A scheduler assigns subgoals to different graphs using weak-to-strong alignment strategies. A two-stage verifier detects structurally invalid and semantically underspecified queries through symbolic validation and counterfactual consistency checks. Experiments on real-world circular economy KGs demonstrate that AgenticT$^2$S improves execution accuracy by 17.3% and triple level F$_1$ by 25.4% over the best baseline, while reducing the average prompt length by 46.4%. These results demonstrate the benefits of agent-based schema-aware reasoning for scalable KGQA and support decision-making in sustainability domains through robust cross-graph reasoning.
3.3AISep 25, 2025
CLAUSE: Agentic Neuro-Symbolic Knowledge Graph Reasoning via Dynamic Learnable Context EngineeringYang Zhao, Chengxiao Dai, Wei Zhuo et al.
Knowledge graphs provide structured context for multi-hop question answering, but deployed systems must balance answer accuracy with strict latency and cost targets while preserving provenance. Static k-hop expansions and "think-longer" prompting often over-retrieve, inflate context, and yield unpredictable runtime. We introduce CLAUSE, an agentic three-agent neuro-symbolic framework that treats context construction as a sequential decision process over knowledge graphs, deciding what to expand, which paths to follow or backtrack, what evidence to keep, and when to stop. Latency (interaction steps) and prompt cost (selected tokens) are exposed as user-specified budgets or prices, allowing per-query adaptation to trade-offs among accuracy, latency, and cost without retraining. CLAUSE employs the proposed Lagrangian-Constrained Multi-Agent Proximal Policy Optimization (LC-MAPPO) algorithm to coordinate three agents: Subgraph Architect, Path Navigator, and Context Curator, so that subgraph construction, reasoning-path discovery, and evidence selection are jointly optimized under per-query resource budgets on edge edits, interaction steps, and selected tokens. Across HotpotQA, MetaQA, and FactKG, CLAUSE yields higher EM@1 while reducing subgraph growth and end-to-end latency at equal or lower token budgets. On MetaQA-2-hop, relative to the strongest RAG baseline (GraphRAG), CLAUSE achieves +39.3 EM@1 with 18.6% lower latency and 40.9% lower edge growth. The resulting contexts are compact, provenance-preserving, and deliver predictable performance under deployment constraints.
3.3AIJun 1, 2025
A Graph-Retrieval-Augmented Generation Framework Enhances Decision-Making in the Circular EconomyYang Zhao, Chengxiao Dai, Dusit Niyato et al.
Large language models (LLMs) hold promise for sustainable manufacturing, but often hallucinate industrial codes and emission factors, undermining regulatory and investment decisions. We introduce CircuGraphRAG, a retrieval-augmented generation (RAG) framework that grounds LLMs outputs in a domain-specific knowledge graph for the circular economy. This graph connects 117,380 industrial and waste entities with classification codes and GWP100 emission data, enabling structured multi-hop reasoning. Natural language queries are translated into SPARQL and verified subgraphs are retrieved to ensure accuracy and traceability. Compared with Standalone LLMs and Naive RAG, CircuGraphRAG achieves superior performance in single-hop and multi-hop question answering, with ROUGE-L F1 scores up to 1.0, while baseline scores below 0.08. It also improves efficiency, halving the response time and reducing token usage by 16% in representative tasks. CircuGraphRAG provides fact-checked, regulatory-ready support for circular economy planning, advancing reliable, low-carbon resource decision making.