Ming Li

Ming Li, Jike Zhong, Chenxin Li et al.

Recent advances in fine-tuning Vision-Language Models (VLMs) have witnessed the success of prompt tuning and adapter tuning, while the classic model fine-tuning on inherent parameters seems to be overlooked. It is believed that fine-tuning the parameters of VLMs with few-shot samples corrupts the pre-trained knowledge since fine-tuning the CLIP model even degrades performance. In this paper, we revisit this viewpoint, and propose a new perspective: fine-tuning the specific parameters instead of all will uncover the power of classic model fine-tuning on VLMs. Through our meticulous study, we propose ClipFit, a simple yet effective method to fine-tune CLIP without introducing any overhead of extra parameters. We demonstrate that by only fine-tuning the specific bias terms and normalization layers, ClipFit can improve the performance of zero-shot CLIP by 7.27\% average harmonic mean accuracy. Lastly, to understand how fine-tuning in CLIPFit affects the pre-trained models, we conducted extensive experimental analyses w.r.t. changes in internal parameters and representations. We found that low-level text bias layers and the first layer normalization layer change much more than other layers. The code is available at \url{https://github.com/minglllli/CLIPFit}.

Ming Li, Pengcheng Xu, Junjie Hu et al.

Federated learning holds great potential for enabling large-scale healthcare research and collaboration across multiple centres while ensuring data privacy and security are not compromised. Although numerous recent studies suggest or utilize federated learning based methods in healthcare, it remains unclear which ones have potential clinical utility. This review paper considers and analyzes the most recent studies up to May 2024 that describe federated learning based methods in healthcare. After a thorough review, we find that the vast majority are not appropriate for clinical use due to their methodological flaws and/or underlying biases which include but are not limited to privacy concerns, generalization issues, and communication costs. As a result, the effectiveness of federated learning in healthcare is significantly compromised. To overcome these challenges, we provide recommendations and promising opportunities that might be implemented to resolve these problems and improve the quality of model development in federated learning with healthcare.

Ming Li, Keyu Chen, Ziqian Bi et al.

The rise of Multimodal Large Language Models (MLLMs) has become a transformative force in the field of artificial intelligence, enabling machines to process and generate content across multiple modalities, such as text, images, audio, and video. These models represent a significant advancement over traditional unimodal systems, opening new frontiers in diverse applications ranging from autonomous agents to medical diagnostics. By integrating multiple modalities, MLLMs achieve a more holistic understanding of information, closely mimicking human perception. As the capabilities of MLLMs expand, the need for comprehensive and accurate performance evaluation has become increasingly critical. This survey aims to provide a systematic review of benchmark tests and evaluation methods for MLLMs, covering key topics such as foundational concepts, applications, evaluation methodologies, ethical concerns, security, efficiency, and domain-specific applications. Through the classification and analysis of existing literature, we summarize the main contributions and methodologies of various surveys, conduct a detailed comparative analysis, and examine their impact within the academic community. Additionally, we identify emerging trends and underexplored areas in MLLM research, proposing potential directions for future studies. This survey is intended to offer researchers and practitioners a comprehensive understanding of the current state of MLLM evaluation, thereby facilitating further progress in this rapidly evolving field.

Qian Niu, Keyu Chen, Ming Li et al.

Large Language Models (LLMs) have rapidly evolved from text-based systems to multimodal platforms, significantly impacting various sectors including healthcare. This comprehensive review explores the progression of LLMs to Multimodal Large Language Models (MLLMs) and their growing influence in medical practice. We examine the current landscape of MLLMs in healthcare, analyzing their applications across clinical decision support, medical imaging, patient engagement, and research. The review highlights the unique capabilities of MLLMs in integrating diverse data types, such as text, images, and audio, to provide more comprehensive insights into patient health. We also address the challenges facing MLLM implementation, including data limitations, technical hurdles, and ethical considerations. By identifying key research gaps, this paper aims to guide future investigations in areas such as dataset development, modality alignment methods, and the establishment of ethical guidelines. As MLLMs continue to shape the future of healthcare, understanding their potential and limitations is crucial for their responsible and effective integration into medical practice.

Jie Zhao, Ming Li, Yu Li et al.

Understanding the extent of urban flooding is crucial for assessing building damage, casualties and economic losses. Synthetic Aperture Radar (SAR) technology offers significant advantages for mapping flooded urban areas due to its ability to collect data regardless weather and solar illumination conditions. However, the wide range of existing methods makes it difficult to choose the best approach for a specific situation and to identify future research directions. Therefore, this study provides a comprehensive review of current research on urban flood mapping using SAR data, summarizing key characteristics of floodwater in SAR images and outlining various approaches from scientific articles. Additionally, we provide a brief overview of the advantages and disadvantages of each method category, along with guidance on selecting the most suitable approach for different scenarios. This study focuses on the challenges and advancements in SAR-based urban flood mapping. It specifically addresses the limitations of spatial and temporal resolution in SAR data and discusses the essential pre-processing steps. Moreover, the article explores the potential benefits of Polarimetric SAR (PolSAR) techniques and uncertainty analysis for future research. Furthermore, it highlights a lack of open-access SAR datasets for urban flood mapping, hindering development in advanced deep learning-based methods. Besides, we evaluated the Technology Readiness Levels (TRLs) of urban flood mapping techniques to identify challenges and future research areas. Finally, the study explores the practical applications of SAR-based urban flood mapping in both the private and public sectors and provides a comprehensive overview of the benefits and potential impact of these methods.

Zheng Ma, Zeping Mao, Ruixue Zhang et al.

Data-Independent Acquisition (DIA) was introduced to improve sensitivity to cover all peptides in a range rather than only sampling high-intensity peaks as in Data-Dependent Acquisition (DDA) mass spectrometry. However, it is not very clear how useful DIA data is for de novo peptide sequencing as the DIA data are marred with coeluted peptides, high noises, and varying data quality. We present a new deep learning method DIANovo, and address each of these difficulties, and improves the previous established systems by a large margin, via equipping the model with a deeper understanding of coeluted DIA spectra. This paper also provides criteria about when DIA data could be used for de novo peptide sequencing and when not to by providing a comparison between DDA and DIA, in both de novo and database search mode. We find that while DIA excels with narrow isolation windows on older-generation instruments, it loses its advantage with wider windows. However, with Orbitrap Astral, DIA consistently outperforms DDA due to narrow window mode enabled. We also provide a theoretical explanation of this phenomenon, emphasizing the critical role of the signal-to-noise profile in the successful application of de novo sequencing.