Jinxin Zhu

Sriram Yenamandra, Arun Ramachandran, Mukul Khanna et al. · cmu

In order to develop robots that can effectively serve as versatile and capable home assistants, it is crucial for them to reliably perceive and interact with a wide variety of objects across diverse environments. To this end, we proposed Open Vocabulary Mobile Manipulation as a key benchmark task for robotics: finding any object in a novel environment and placing it on any receptacle surface within that environment. We organized a NeurIPS 2023 competition featuring both simulation and real-world components to evaluate solutions to this task. Our baselines on the most challenging version of this task, using real perception in simulation, achieved only an 0.8% success rate; by the end of the competition, the best participants achieved an 10.8\% success rate, a 13x improvement. We observed that the most successful teams employed a variety of methods, yet two common threads emerged among the best solutions: enhancing error detection and recovery, and improving the integration of perception with decision-making processes. In this paper, we detail the results and methodologies used, both in simulation and real-world settings. We discuss the lessons learned and their implications for future research. Additionally, we compare performance in real and simulated environments, emphasizing the necessity for robust generalization to novel settings.

Xuesheng Bian, Cheng Wang, Shuting Chen et al.

Adenosine triphosphate (ATP) is a high-energy phosphate compound and the most direct energy source in organisms. ATP is an essential biomarker for evaluating cell viability in biology. Researchers often use ATP bioluminescence to measure the ATP of organoid after drug to evaluate the drug efficacy. However, ATP bioluminescence has some limitations, leading to unreliable drug screening results. Performing ATP bioluminescence causes cell lysis of organoids, so it is impossible to observe organoids' long-term viability changes after medication continually. To overcome the disadvantages of ATP bioluminescence, we propose Ins-ATP, a non-invasive strategy, the first organoid ATP estimation model based on the high-throughput microscopic image. Ins-ATP directly estimates the ATP of organoids from high-throughput microscopic images, so that it does not influence the drug reactions of organoids. Therefore, the ATP change of organoids can be observed for a long time to obtain more stable results. Experimental results show that the ATP estimation by Ins-ATP is in good agreement with those determined by ATP bioluminescence. Specifically, the predictions of Ins-ATP are consistent with the results measured by ATP bioluminescence in the efficacy evaluation experiments of different drugs.

Yongzhi Huang, Fengjun Xi, Liyun Tu et al.

Accurate segmentation of multiple organs in Computed Tomography (CT) images plays a vital role in computer-aided diagnosis systems. While various supervised learning approaches have been proposed recently, these methods heavily depend on a large amount of high-quality labeled data, which are expensive to obtain in practice. To address this challenge, we propose a label-efficient framework using knowledge transfer from a pre-trained diffusion model for CT multi-organ segmentation. Specifically, we first pre-train a denoising diffusion model on 207,029 unlabeled 2D CT slices to capture anatomical patterns. Then, the model backbone is transferred to the downstream multi-organ segmentation task, followed by fine-tuning with few labeled data. In fine-tuning, two fine-tuning strategies, linear classification and fine-tuning decoder, are employed to enhance segmentation performance while preserving learned representations. Quantitative results show that the pre-trained diffusion model is capable of generating diverse and realistic 256x256 CT images (Fréchet inception distance (FID): 11.32, spatial Fréchet inception distance (sFID): 46.93, F1-score: 73.1%). Compared to state-of-the-art methods for multi-organ segmentation, our method achieves competitive performance on the FLARE 2022 dataset, particularly in limited labeled data scenarios. After fine-tuning with 1% and 10% labeled data, our method achieves dice similarity coefficients (DSCs) of 71.56% and 78.51%, respectively. Remarkably, the method achieves a DSC score of 51.81% using only four labeled CT slices. These results demonstrate the efficacy of our approach in overcoming the limitations of supervised learning approaches that is highly dependent on large-scale labeled data.