Qianqian Wang

Qianqian Wang, Wei Wang, Yuqi Fang et al.

Resting-state functional magnetic resonance imaging (rs-fMRI) can reflect spontaneous neural activities in brain and is widely used for brain disorder analysis.Previous studies propose to extract fMRI representations through diverse machine/deep learning methods for subsequent analysis. But the learned features typically lack biological interpretability, which limits their clinical utility. From the view of graph theory, the brain exhibits a remarkable modular structure in spontaneous brain functional networks, with each module comprised of functionally interconnected brain regions-of-interest (ROIs). However, most existing learning-based methods for fMRI analysis fail to adequately utilize such brain modularity prior. In this paper, we propose a Brain Modularity-constrained dynamic Representation learning (BMR) framework for interpretable fMRI analysis, consisting of three major components: (1) dynamic graph construction, (2) dynamic graph learning via a novel modularity-constrained graph neural network(MGNN), (3) prediction and biomarker detection for interpretable fMRI analysis. Especially, three core neurocognitive modules (i.e., salience network, central executive network, and default mode network) are explicitly incorporated into the MGNN, encouraging the nodes/ROIs within the same module to share similar representations. To further enhance discriminative ability of learned features, we also encourage the MGNN to preserve the network topology of input graphs via a graph topology reconstruction constraint. Experimental results on 534 subjects with rs-fMRI scans from two datasets validate the effectiveness of the proposed method. The identified discriminative brain ROIs and functional connectivities can be regarded as potential fMRI biomarkers to aid in clinical diagnosis.

Qianqian Wang, Xiaowei Zhou, Bharath Hariharan et al.

Recent research on learned visual descriptors has shown promising improvements in correspondence estimation, a key component of many 3D vision tasks. However, existing descriptor learning frameworks typically require ground-truth correspondences between feature points for training, which are challenging to acquire at scale. In this paper we propose a novel weakly-supervised framework that can learn feature descriptors solely from relative camera poses between images. To do so, we devise both a new loss function that exploits the epipolar constraint given by camera poses, and a new model architecture that makes the whole pipeline differentiable and efficient. Because we no longer need pixel-level ground-truth correspondences, our framework opens up the possibility of training on much larger and more diverse datasets for better and unbiased descriptors. We call the resulting descriptors CAmera Pose Supervised, or CAPS, descriptors. Though trained with weak supervision, CAPS descriptors outperform even prior fully-supervised descriptors and achieve state-of-the-art performance on a variety of geometric tasks. Project Page: https://qianqianwang68.github.io/CAPS/