Tirthak Patel

Daniel Silver, Tirthak Patel, Aditya Ranjan et al.

Exploration into quantum machine learning has grown tremendously in recent years due to the ability of quantum computers to speed up classical programs. However, these efforts have yet to solve unsupervised similarity detection tasks due to the challenge of porting them to run on quantum computers. To overcome this challenge, we propose SLIQ, the first open-sourced work for resource-efficient quantum similarity detection networks, built with practical and effective quantum learning and variance-reducing algorithms.

Baolin Li, Rohan Basu Roy, Tirthak Patel et al.

Deep learning model inference is a key service in many businesses and scientific discovery processes. This paper introduces RIBBON, a novel deep learning inference serving system that meets two competing objectives: quality-of-service (QoS) target and cost-effectiveness. The key idea behind RIBBON is to intelligently employ a diverse set of cloud computing instances (heterogeneous instances) to meet the QoS target and maximize cost savings. RIBBON devises a Bayesian Optimization-driven strategy that helps users build the optimal set of heterogeneous instances for their model inference service needs on cloud computing platforms -- and, RIBBON demonstrates its superiority over existing approaches of inference serving systems using homogeneous instance pools. RIBBON saves up to 16% of the inference service cost for different learning models including emerging deep learning recommender system models and drug-discovery enabling models.

Daniel Silver, Tirthak Patel, Devesh Tiwari

Quantum computers can theoretically have significant acceleration over classical computers; but, the near-future era of quantum computing is limited due to small number of qubits that are also error prone. Quilt is a framework for performing multi-class classification task designed to work effectively on current error-prone quantum computers. Quilt is evaluated with real quantum machines as well as with projected noise levels as quantum machines become more noise-free. Quilt demonstrates up to 85% multi-class classification accuracy with the MNIST dataset on a five-qubit system.

Daniel Silver, Tirthak Patel, William Cutler et al.

Quantum machine learning and vision have come to the fore recently, with hardware advances enabling rapid advancement in the capabilities of quantum machines. Recently, quantum image generation has been explored with many potential advantages over non-quantum techniques; however, previous techniques have suffered from poor quality and robustness. To address these problems, we introduce, MosaiQ, a high-quality quantum image generation GAN framework that can be executed on today's Near-term Intermediate Scale Quantum (NISQ) computers.

Daniel Silver, Tirthak Patel, Devesh Tiwari

As quantum computing architecture matures, it is important to investigate new technologies that lend unique advantages. In this work, we propose, Qompose, a neutral atom quantum computing framework for efficiently composing quantum circuits on 2-D topologies of neutral atoms. Qompose selects an efficient topology for any given circuit in order to optimize for length of execution through efficient parallelism and for overall fidelity. our extensive evaluation demonstrates the Qompose is effective for a large collection of randomly-generated quantum circuits and a range of real-world benchmarks including VQE, ISING, and QAOA.

Daniel Silver, Tirthak Patel, Aditya Ranjan et al.

Driven by swift progress in hardware capabilities, quantum machine learning has emerged as a research area of interest. Recently, quantum image generation has produced promising results. However, prior quantum image generation techniques rely on classical neural networks, limiting their quantum potential and image quality. To overcome this, we introduce OrganiQ, the first quantum GAN capable of producing high-quality images without using classical neural networks.

Jason Ludmir, Nicholas S. DiBrita, Jason Han et al.

Emerging quantum sensors are increasingly envisioned as components of hybrid quantum-classical high-performance computing, enabling new capabilities in scientific, cyber-physical, and machine-learning pipelines. However, their practical utility is limited by environmental decoherence, which degrades sensing reliability. While dynamical decoupling (DD) pulse sequences can mitigate this, standard methods are often suboptimal in the presence of realistic noise. We present SpinTune, a reinforcement learning software approach that autonomously discovers adaptive, piecewise DD sequences tailored to specific environments. Using a simulation model of a Carbon-13 spin bath, we show that SpinTune significantly outperforms standard DD sequences in preserving coherence.

Jason Han, Nicholas S. DiBrita, Younghyun Cho et al.

Amplitude embedding (AE) is essential in quantum machine learning (QML) for encoding classical data onto quantum circuits. However, conventional AE methods suffer from deep, variable-length circuits that introduce high output error due to extensive gate usage and variable error rates across samples, resulting in noise-driven inconsistencies that degrade model accuracy. We introduce EnQode, a fast AE technique based on symbolic representation that addresses these limitations by clustering dataset samples and solving for cluster mean states through a low-depth, machine-specific ansatz. Optimized to reduce physical gates and SWAP operations, EnQode ensures all samples face consistent, low noise levels by standardizing circuit depth and composition. With over 90% fidelity in data mapping, EnQode enables robust, high-performance QML on noisy intermediate-scale quantum (NISQ) devices. Our open-source solution provides a scalable and efficient alternative for integrating classical data with quantum models.

Nicholas S. DiBrita, Daniel Leeds, Yuqian Huo et al.

Quantum computing has shown theoretical promise of speedup in several machine learning tasks, including generative tasks using generative adversarial networks (GANs). While quantum computers have been implemented with different types of technologies, recently, analog Rydberg atom quantum computers have been demonstrated to have desirable properties such as reconfigurable qubit (quantum bit) positions and multi-qubit operations. To leverage the properties of this technology, we propose ReCon, the first work to implement quantum GANs on analog Rydberg atom quantum computers. Our evaluation using simulations and real-computer executions shows 33% better quality (measured using Frechet Inception Distance (FID)) in generated images than the state-of-the-art technique implemented on superconducting-qubit technology.

Mohammad Abrarul Hasanat, Jason Ludmir, Tirthak Patel et al.

Quantum processors are being integrated into HPC ecosystems as co-processors, where compilation of quantum circuits into hardware-executable form determines both output fidelity and runtime. Current compilers use a fixed pass sequence and ignore the fact that optimal pass selection varies with circuit, hardware, and noise conditions. We present TuniQ, a reinforcement learning-based system that selects compilation passes at each pipeline stage, adapting to circuit, backend, and current noise profile. TuniQ introduces several novel design components like a dual-encoder for stage-aware representation, shaped rewards for cross-stage credit assignment, and dynamic action masking for valid compilation. Evaluated across diverse quantum workloads on multiple IBM Quantum Cloud processors, TuniQ improves fidelity and reduces compilation time over the state-of-the-art IBM Qiskit transpiler, generalizes across backends without retraining, and scales strongly to utility-scale circuits with growing advantage.

Christopher Kverne, Mayur Akewar, Yuqian Huo et al.

The training of Quantum Neural Networks (QNNs) is hindered by the high computational cost of gradient estimation and the barren plateau problem, where optimization landscapes become intractably flat. To address these challenges, we introduce Weighted Stochastic Block Descent (WSBD), a novel optimizer with a dynamic, parameter-wise freezing strategy. WSBD intelligently focuses computational resources by identifying and temporarily freezing less influential parameters based on a gradient-derived importance score. This approach significantly reduces the number of forward passes required per training step and helps navigate the optimization landscape more effectively. Unlike pruning or layer-wise freezing, WSBD maintains full expressive capacity while adapting throughout training. Our extensive evaluation shows that WSBD converges on average 63.9% faster than Adam for the popular ground-state-energy problem, an advantage that grows with QNN size. We provide a formal convergence proof for WSBD and show that parameter-wise freezing outperforms traditional layer-wise approaches in QNNs. Project page: https://github.com/Damrl-lab/WSBD-Stochastic-Freezing-Optimizer.

Jason Ludmir, Ian Martin, Nicholas S. DiBrita et al.

Quantum machine learning (QML) promises significant speedups, particularly when operating on quantum datasets. However, its progress is hindered by the scarcity of suitable training data. Existing synthetic data generation methods fall short in capturing essential entanglement properties, limiting their utility for QML. To address this, we introduce QuFoundry, a low-depth quantum data generation framework that produces entangled, high-quality samples emulating diverse classical and quantum distributions, enabling more effective development and evaluation of QML models in representative-data settings.

Nicholas S. DiBrita, Jason Han, Tirthak Patel

Research in quantum machine learning has recently proliferated due to the potential of quantum computing to accelerate machine learning. An area of machine learning that has not yet been explored is neural ordinary differential equation (neural ODE) based residual neural networks (ResNets), which aim to improve the effectiveness of neural networks using the principles of ordinary differential equations. In this work, we present our insights about why analog Rydberg atom quantum computers are especially well-suited for ResNets. We also introduce ResQ, a novel framework to optimize the dynamics of Rydberg atom quantum computers to solve classification problems in machine learning using analog quantum neural ODEs.

Jason Zev Ludmir, Sophia Rebello, Jacob Ruiz et al.

Detecting mission-critical anomalous events and data is a crucial challenge across various industries, including finance, healthcare, and energy. Quantum computing has recently emerged as a powerful tool for tackling several machine learning tasks, but training quantum machine learning models remains challenging, particularly due to the difficulty of gradient calculation. The challenge is even greater for anomaly detection, where unsupervised learning methods are essential to ensure practical applicability. To address these issues, we propose Quorum, the first quantum anomaly detection framework designed for unsupervised learning that operates without requiring any training.

Yuqian Huo, David Quiroga, Anastasios Kyrillidis et al.

Variational quantum algorithms (VQAs) have the potential to demonstrate quantum utility on near-term quantum computers. However, these algorithms often get executed on the highest-fidelity qubits and computers to achieve the best performance, causing low system throughput. Recent efforts have shown that VQAs can be run on low-fidelity qubits initially and high-fidelity qubits later on to still achieve good performance. We take this effort forward and show that carefully varying the qubit fidelity map of the VQA over its execution using our technique, Nest, does not just (1) improve performance (i.e., help achieve close to optimal results), but also (2) lead to faster convergence. We also use Nest to co-locate multiple VQAs concurrently on the same computer, thus (3) increasing the system throughput, and therefore, balancing and optimizing three conflicting metrics simultaneously.

Jason Han, Nicholas S. DiBrita, Daniel Leeds et al.

Quantum machine learning (QML) holds the promise to solve classically intractable problems, but, as critical data can be fragmented across private clients, there is a need for distributed QML in a quantum federated learning (QFL) format. However, the quantum computers that different clients have access to can be error-prone and have heterogeneous error properties, requiring them to run circuits of different depths. We propose a novel solution to this QFL problem, Quorus, that utilizes a layerwise loss function for effective training of varying-depth quantum models, which allows clients to choose models for high-fidelity output based on their individual capacity. Quorus also presents various model designs based on client needs that optimize for shot budget, qubit count, midcircuit measurement, and optimization space. Our simulation and real-hardware results show the promise of Quorus: it increases the magnitude of gradients of higher depth clients and improves testing accuracy by 12.4% on average over the state-of-the-art.