Monica Agrawal

Sraavya Sambara, Yuan Pu, Ayman Ali et al.

Real-world health questions from patients often unintentionally embed false assumptions or premises. In such cases, safe medical communication typically involves redirection: addressing the implicit misconception and then responding to the underlying patient context, rather than the original question. While large language models (LLMs) are increasingly being used by lay users for medical advice, they have not yet been tested for this crucial competency. Therefore, in this work, we investigate how LLMs react to false premises embedded within real-world health questions. We develop a semi-automated pipeline to curate MedRedFlag, a dataset of 1100+ questions sourced from Reddit that require redirection. We then systematically compare responses from state-of-the-art LLMs to those from clinicians. Our analysis reveals that LLMs often fail to redirect problematic questions, even when the problematic premise is detected, and provide answers that could lead to suboptimal medical decision making. Our benchmark and results reveal a novel and substantial gap in how LLMs perform under the conditions of real-world health communication, highlighting critical safety concerns for patient-facing medical AI systems. Code and dataset are available at https://github.com/srsambara-1/MedRedFlag.

Raymond Xiong, Furong Jia, Lionel Wong et al.

Patients are increasingly using large language models (LLMs) to seek answers to their healthcare-related questions. However, benchmarking efforts in LLMs for question answering often focus on medical exam questions, which differ significantly in style and content from the questions patients actually raise in real life. To bridge this gap, we sourced data from Google's People Also Ask feature by querying the top 200 prescribed medications in the United States, curating a dataset of medical questions people commonly ask. A considerable portion of the collected questions contains incorrect assumptions and dangerous intentions. We demonstrate that the emergence of these corrupted questions is not uniformly random and depends heavily on the degree of incorrectness in the history of questions that led to their appearance. Current LLMs that perform strongly on other benchmarks struggle to identify incorrect assumptions in everyday questions.