Yubin Xiao

Ye Wang, Rui Ma, Xiaoqing Ma et al.

Fine-grained classification and counting of bone marrow erythroid cells are vital for evaluating the health status and formulating therapeutic schedules for leukemia or hematopathy. Due to the subtle visual differences between different types of erythroid cells, it is challenging to apply existing image-based deep learning models for fine-grained erythroid cell classification. Moreover, there is no large open-source datasets on erythroid cells to support the model training. In this paper, we introduce BMEC (Bone Morrow Erythroid Cells), the first large fine-grained image dataset of erythroid cells, to facilitate more deep learning research on erythroid cells. BMEC contains 5,666 images of individual erythroid cells, each of which is extracted from the bone marrow erythroid cell smears and professionally annotated to one of the four types of erythroid cells. To distinguish the erythroid cells, one key indicator is the cell shape which is closely related to the cell growth and maturation. Therefore, we design a novel shape-aware image classification network for fine-grained erythroid cell classification. The shape feature is extracted from the shape mask image and aggregated to the raw image feature with a shape attention module. With the shape-attended image feature, our network achieved superior classification performance (81.12\% top-1 accuracy) on the BMEC dataset comparing to the baseline methods. Ablation studies also demonstrate the effectiveness of incorporating the shape information for the fine-grained cell classification. To further verify the generalizability of our method, we tested our network on two additional public white blood cells (WBC) datasets and the results show our shape-aware method can generally outperform recent state-of-the-art works on classifying the WBC. The code and BMEC dataset can be found on https://github.com/wangye8899/BMEC.

Yubin Xiao, Di Wang, Boyang Li et al.

The Traveling Salesman Problem (TSP) is a well-known combinatorial optimization problem with broad real-world applications. Recently, neural networks have gained popularity in this research area because as shown in the literature, they provide strong heuristic solutions to TSPs. Compared to autoregressive neural approaches, non-autoregressive (NAR) networks exploit the inference parallelism to elevate inference speed but suffer from comparatively low solution quality. In this paper, we propose a novel NAR model named NAR4TSP, which incorporates a specially designed architecture and an enhanced reinforcement learning strategy. To the best of our knowledge, NAR4TSP is the first TSP solver that successfully combines RL and NAR networks. The key lies in the incorporation of NAR network output decoding into the training process. NAR4TSP efficiently represents TSP encoded information as rewards and seamlessly integrates it into reinforcement learning strategies, while maintaining consistent TSP sequence constraints during both training and testing phases. Experimental results on both synthetic and real-world TSPs demonstrate that NAR4TSP outperforms five state-of-the-art models in terms of solution quality, inference speed, and generalization to unseen scenarios.

Xuan Wu, Jinbiao Chen, Yang Li et al.

Existing neural solvers for Multi-Objective Combinatorial Optimization Problems (MOCOPs) commonly adopt decomposition-based strategies that scalarize an MOCOP into multiple subproblems associated with distinct weight vectors. However, they either inject weights only once during decoding, limiting weight-conditioned context modeling, or primarily during encoding, causing weight-signal dilution during decoding. Moreover, preference optimization methods rely on purely random sampling to construct solution pairs for training solvers, which often produces less informative pairs and thus leads to low training effectiveness. To better address these limitations, we propose an efficient Weight-Conditioned neural solver (WeCon). Specifically, we design an encoder layer with three attention blocks and our proposed Gated Residual Fusion (GRF) block to facilitate harmonious interaction between instance features and weights, thereby generating informative weight-conditioned context. We further introduce a plug-and-play Residual Fusion (RF) block in the decoder to alleviate weight-signal dilution. Finally, we propose Efficient Preference Optimization (EPO), which constructs high-quality solutions, thereby generating more informative pairs to improve training effectiveness. Experiments on four MOCOP variants across different problem scales and distribution patterns demonstrate that WeCon achieves HyperVolume (HV) values comparable to SOTA solver POCCO-W, while reducing inference time by 40%. Ablation studies validate the contributions of all designs.

Mingzhao Wang, You Zhou, Zhiguang Cao et al.

Recent advances in neural models have shown considerable promise in solving Traveling Salesman Problems (TSPs) without relying on much hand-crafted engineering. However, while non-autoregressive (NAR) approaches benefit from faster inference through parallelism, they typically deliver solutions of inferior quality compared to autoregressive ones. To enhance the solution quality while maintaining fast inference, we propose DEITSP, a diffusion model with efficient iterations tailored for TSP that operates in a NAR manner. Firstly, we introduce a one-step diffusion model that integrates the controlled discrete noise addition process with self-consistency enhancement, enabling optimal solution prediction through simultaneous denoising of multiple solutions. Secondly, we design a dual-modality graph transformer to bolster the extraction and fusion of features from node and edge modalities, while further accelerating the inference with fewer layers. Thirdly, we develop an efficient iterative strategy that alternates between adding and removing noise to improve exploration compared to previous diffusion methods. Additionally, we devise a scheduling framework to progressively refine the solution space by adjusting noise levels, facilitating a smooth search for optimal solutions. Extensive experiments on real-world and large-scale TSP instances demonstrate that DEITSP performs favorably against existing neural approaches in terms of solution quality, inference latency, and generalization ability. Our code is available at $\href{https://github.com/DEITSP/DEITSP}{https://github.com/DEITSP/DEITSP}$.

Jiaqi Wang, Zhiguang Cao, Peng Zhao et al.

The rise of smart manufacturing under Industry 4.0 introduces mass customization and dynamic production, demanding more advanced and flexible scheduling techniques. The flexible job-shop scheduling problem (FJSP) has attracted significant attention due to its complex constraints and strong alignment with real-world production scenarios. Current deep reinforcement learning (DRL)-based approaches to FJSP predominantly employ constructive methods. While effective, they often fall short of reaching (near-)optimal solutions. In contrast, improvement-based methods iteratively explore the neighborhood of initial solutions and are more effective in approaching optimality. However, the flexible machine allocation in FJSP poses significant challenges to the application of this framework, including accurate state representation, effective policy learning, and efficient search strategies. To address these challenges, this paper proposes a Memory-enhanced Improvement Search framework with heterogeneous graph representation--MIStar. It employs a novel heterogeneous disjunctive graph that explicitly models the operation sequences on machines to accurately represent scheduling solutions. Moreover, a memoryenhanced heterogeneous graph neural network (MHGNN) is designed for feature extraction, leveraging historical trajectories to enhance the decision-making capability of the policy network. Finally, a parallel greedy search strategy is adopted to explore the solution space, enabling superior solutions with fewer iterations. Extensive experiments on synthetic data and public benchmarks demonstrate that MIStar significantly outperforms both traditional handcrafted improvement heuristics and state-of-the-art DRL-based constructive methods.

Yubin Xiao, Di Wang, Boyang Li et al.

Neural construction models have shown promising performance for Vehicle Routing Problems (VRPs) by adopting either the Autoregressive (AR) or Non-Autoregressive (NAR) learning approach. While AR models produce high-quality solutions, they generally have a high inference latency due to their sequential generation nature. Conversely, NAR models generate solutions in parallel with a low inference latency but generally exhibit inferior performance. In this paper, we propose a generic Guided Non-Autoregressive Knowledge Distillation (GNARKD) method to obtain high-performance NAR models having a low inference latency. GNARKD removes the constraint of sequential generation in AR models while preserving the learned pivotal components in the network architecture to obtain the corresponding NAR models through knowledge distillation. We evaluate GNARKD by applying it to three widely adopted AR models to obtain NAR VRP solvers for both synthesized and real-world instances. The experimental results demonstrate that GNARKD significantly reduces the inference time (4-5 times faster) with acceptable performance drop (2-3\%). To the best of our knowledge, this study is first-of-its-kind to obtain NAR VRP solvers from AR ones through knowledge distillation.

Hao Li, Yubin Xiao, Ke Liang et al.

Single Domain Generalization (SDG) aims to train models with consistent performance across diverse scenarios using data from a single source. While using latent diffusion models (LDMs) show promise in augmenting limited source data, we demonstrate that directly using synthetic data can be detrimental due to significant feature distribution discrepancies between synthetic and real target domains, leading to performance degradation. To address this issue, we propose Discriminative Domain Reassembly and Soft-Fusion (DRSF), a training framework leveraging synthetic data to improve model generalization. We employ LDMs to produce diverse pseudo-target domain samples and introduce two key modules to handle distribution bias. First, Discriminative Feature Decoupling and Reassembly (DFDR) module uses entropy-guided attention to recalibrate channel-level features, suppressing synthetic noise while preserving semantic consistency. Second, Multi-pseudo-domain Soft Fusion (MDSF) module uses adversarial training with latent-space feature interpolation, creating continuous feature transitions between domains. Extensive SDG experiments on object detection and semantic segmentation tasks demonstrate that DRSF achieves substantial performance gains with only marginal computational overhead. Notably, DRSF's plug-and-play architecture enables seamless integration with unsupervised domain adaptation paradigms, underscoring its broad applicability in addressing diverse and real-world domain challenges.

Wenhao Song, Xuan Wu, Bo Yang et al.

To address the weight coupling problem, certain studies introduced few-shot Neural Architecture Search (NAS) methods, which partition the supernet into multiple sub-supernets. However, these methods often suffer from computational inefficiency and tend to provide suboptimal partitioning schemes. To address this problem more effectively, we analyze the weight coupling problem from a novel perspective, which primarily stems from distinct modules in succeeding layers imposing conflicting gradient directions on the preceding layer modules. Based on this perspective, we propose the Gradient Contribution (GC) method that efficiently computes the cosine similarity of gradient directions among modules by decomposing the Vector-Jacobian Product during supernet backpropagation. Subsequently, the modules with conflicting gradient directions are allocated to distinct sub-supernets while similar ones are grouped together. To assess the advantages of GC and address the limitations of existing Graph Neural Architecture Search methods, which are limited to searching a single type of Graph Neural Networks (Message Passing Neural Networks (MPNNs) or Graph Transformers (GTs)), we propose the Unified Graph Neural Architecture Search (UGAS) framework, which explores optimal combinations of MPNNs and GTs. The experimental results demonstrate that GC achieves state-of-the-art (SOTA) performance in supernet partitioning quality and time efficiency. In addition, the architectures searched by UGAS+GC outperform both the manually designed GNNs and those obtained by existing NAS methods. Finally, ablation studies further demonstrate the effectiveness of all proposed methods.

Heming Wu, Di Wang, Tai Ma et al.

Although pyramid networks have demonstrated superior performance in deformable medical image registration, their decoder architectures are inherently prone to propagating and accumulating anatomical structure misalignments. Moreover, most existing models do not adaptively determine the number of iterations for optimization under varying deformation requirements across images, resulting in either premature termination or excessive iterations that degrades registration accuracy. To effectively mitigate the accumulation of anatomical misalignments, we propose the Feature-Enhanced Residual Module (FERM) as the core component of each decoding layer in the pyramid network. FERM comprises three sequential blocks that extract anatomical semantic features, learn to suppress irrelevant features, and estimate the final deformation field, respectively. To adaptively determine the number of iterations for varying images, we propose the dual-stage Threshold-Controlled Iterative (TCI) strategy. In the first stage, TCI assesses registration stability and with asserted stability, it continues with the second stage to evaluate convergence. We coin the model that integrates FERM and TCI as Threshold-Controlled Iterative Pyramid (TCIP). Extensive experiments on three public brain MRI datasets and one abdomen CT dataset demonstrate that TCIP outperforms the state-of-the-art (SOTA) registration networks in terms of accuracy, while maintaining comparable inference speed and a compact model parameter size. Finally, we assess the generalizability of FERM and TCI by integrating them with existing registration networks and further conduct ablation studies to validate the effectiveness of these two proposed methods.

Xuan Wu, Di Wang, Chunguo Wu et al.

Numerous Neural Combinatorial Optimization (NCO) solvers have been proposed to address Vehicle Routing Problems (VRPs). However, most of these solvers focus exclusively on single-vehicle VRP variants, overlooking the more realistic min-max Heterogeneous Capacitated Vehicle Routing Problem (MMHCVRP), which involves multiple vehicles. Existing MMHCVRP solvers typically select a vehicle and its next node to visit at each decoding step, but often make myopic decoding decisions and overlook key properties of MMHCVRP, including local topological relationships, vehicle permutation invariance, and node symmetry, resulting in suboptimal performance. To better address these limitations, we propose ECHO, an efficient NCO solver. First, ECHO exploits the proposed dual-modality node encoder to capture local topological relationships among nodes. Subsequently, to mitigate myopic decisions, ECHO employs the proposed Parameter-Free Cross-Attention mechanism to prioritize the vehicle selected in the preceding decoding step. Finally, leveraging vehicle permutation invariance and node symmetry, we introduce a tailored data augment strategy for MMHCVRP to stabilize the Reinforcement Learning training process. To assess the performance of ECHO, we conduct extensive experiments. The experimental results demonstrate that ECHO outperforms state-of-the-art NCO solvers across varying numbers of vehicles and nodes, and exhibits well-performing generalization across both scales and distribution patterns. Finally, ablation studies validate the effectiveness of all proposed methods.

Yubin Xiao, Di Wang, Xuan Wu et al.

Neural models produce promising results when solving Vehicle Routing Problems (VRPs), but often fall short in generalization. Recent attempts to enhance model generalization often incur unnecessarily large training cost or cannot be directly applied to other models solving different VRP variants. To address these issues, we take a novel perspective on model architecture in this study. Specifically, we propose a plug-and-play Entropy-based Scaling Factor (ESF) and a Distribution-Specific (DS) decoder to enhance the size and distribution generalization, respectively. ESF adjusts the attention weight pattern of the model towards familiar ones discovered during training when solving VRPs of varying sizes. The DS decoder explicitly models VRPs of multiple training distribution patterns through multiple auxiliary light decoders, expanding the model representation space to encompass a broader range of distributional scenarios. We conduct extensive experiments on both synthetic and widely recognized real-world benchmarking datasets and compare the performance with seven baseline models. The results demonstrate the effectiveness of using ESF and DS decoder to obtain a more generalizable model and showcase their applicability to solve different VRP variants, i.e., travelling salesman problem and capacitated VRP. Notably, our proposed generic components require minimal computational resources, and can be effortlessly integrated into conventional generalization strategies to further elevate model generalization.

Xuan Wu, Di Wang, Lijie Wen et al.

Although several surveys on Neural Combinatorial Optimization (NCO) solvers specifically designed to solve Vehicle Routing Problems (VRPs) have been conducted, they did not cover the state-of-the-art (SOTA) NCO solvers emerged recently. More importantly, to establish a comprehensive and up-to-date taxonomy of NCO solvers, we systematically review relevant publications and preprints, categorizing them into four distinct types, namely Learning to Construct, Learning to Improve, Learning to Predict-Once, and Learning to Predict-Multiplicity solvers. Subsequently, we present the inadequacies of the SOTA solvers, including poor generalization, incapability to solve large-scale VRPs, inability to address most types of VRP variants simultaneously, and difficulty in comparing these NCO solvers with the conventional Operations Research algorithms. Simultaneously, we discuss on-going efforts, identify open inadequacies, as well as propose promising and viable directions to overcome these inadequacies. Notably, existing efforts focus on only one or two of these inadequacies, with none attempting to address all of them concurrently. In addition, we compare the performance of representative NCO solvers from the Reinforcement, Supervised, and Unsupervised Learning paradigms across VRPs of varying scales. Finally, following the proposed taxonomy, we provide an accompanying web page as a live repository for NCO solvers. Through this survey and the live repository, we aim to foster further advancements in the NCO community.