Junhao Dong

Junhao Dong, Junxi Chen, Xiaohua Xie et al.

Deep learning techniques have achieved superior performance in computer-aided medical image analysis, yet they are still vulnerable to imperceptible adversarial attacks, resulting in potential misdiagnosis in clinical practice. Oppositely, recent years have also witnessed remarkable progress in defense against these tailored adversarial examples in deep medical diagnosis systems. In this exposition, we present a comprehensive survey on recent advances in adversarial attacks and defenses for medical image analysis with a systematic taxonomy in terms of the application scenario. We also provide a unified framework for different types of adversarial attack and defense methods in the context of medical image analysis. For a fair comparison, we establish a new benchmark for adversarially robust medical diagnosis models obtained by adversarial training under various scenarios. To the best of our knowledge, this is the first survey paper that provides a thorough evaluation of adversarially robust medical diagnosis models. By analyzing qualitative and quantitative results, we conclude this survey with a detailed discussion of current challenges for adversarial attack and defense in medical image analysis systems to shed light on future research directions. Code is available on \href{https://github.com/tomvii/Adv_MIA}{\color{red}{GitHub}}.

Junhao Dong, Yuan Wang, Jianhuang Lai et al.

DeepFake face swapping presents a significant threat to online security and social media, which can replace the source face in an arbitrary photo/video with the target face of an entirely different person. In order to prevent this fraud, some researchers have begun to study the adversarial methods against DeepFake or face manipulation. However, existing works focus on the white-box setting or the black-box setting driven by abundant queries, which severely limits the practical application of these methods. To tackle this problem, we introduce a practical adversarial attack that does not require any queries to the facial image forgery model. Our method is built on a substitute model persuing for face reconstruction and then transfers adversarial examples from the substitute model directly to inaccessible black-box DeepFake models. Specially, we propose the Transferable Cycle Adversary Generative Adversarial Network (TCA-GAN) to construct the adversarial perturbation for disrupting unknown DeepFake systems. We also present a novel post-regularization module for enhancing the transferability of generated adversarial examples. To comprehensively measure the effectiveness of our approaches, we construct a challenging benchmark of DeepFake adversarial attacks for future development. Extensive experiments impressively show that the proposed adversarial attack method makes the visual quality of DeepFake face images plummet so that they are easier to be detected by humans and algorithms. Moreover, we demonstrate that the proposed algorithm can be generalized to offer face image protection against various face translation methods.

Junhao Dong, Seyed-Mohsen Moosavi-Dezfooli, Jianhuang Lai et al.

Although current deep learning techniques have yielded superior performance on various computer vision tasks, yet they are still vulnerable to adversarial examples. Adversarial training and its variants have been shown to be the most effective approaches to defend against adversarial examples. These methods usually regularize the difference between output probabilities for an adversarial and its corresponding natural example. However, it may have a negative impact if the model misclassifies a natural example. To circumvent this issue, we propose a novel adversarial training scheme that encourages the model to produce similar outputs for an adversarial example and its ``inverse adversarial'' counterpart. These samples are generated to maximize the likelihood in the neighborhood of natural examples. Extensive experiments on various vision datasets and architectures demonstrate that our training method achieves state-of-the-art robustness as well as natural accuracy. Furthermore, using a universal version of inverse adversarial examples, we improve the performance of single-step adversarial training techniques at a low computational cost.

Zhu Meng, Junhao Dong, Limei Guo et al.

Signet ring cells (SRCs), associated with a high propensity for peripheral metastasis and poor prognosis, critically influence surgical decision-making and outcome prediction. However, their detection remains challenging even for experienced pathologists. While artificial intelligence (AI)-based automated SRC diagnosis has gained increasing attention for its potential to enhance diagnostic efficiency and accuracy, existing methodologies lack systematic review. This gap impedes the assessment of disparities between algorithmic capabilities and clinical applicability. This paper presents a comprehensive survey of AI-driven SRC analysis from 2008 through June 2025. We systematically summarize the biological characteristics of SRCs and challenges in their automated identification. Representative algorithms are analyzed and categorized as unimodal or multi-modal approaches. Unimodal algorithms, encompassing image, omics, and text data, are reviewed; image-based ones are further subdivided into classification, detection, segmentation, and foundation model tasks. Multi-modal algorithms integrate two or more data modalities (images, omics, and text). Finally, by evaluating current methodological performance against clinical assistance requirements, we discuss unresolved challenges and future research directions in SRC analysis. This survey aims to assist researchers, particularly those without medical backgrounds, in understanding the landscape of SRC analysis and the prospects for intelligent diagnosis, thereby accelerating the translation of computational algorithms into clinical practice.

Yuqi Li, Kai Li, Xin Yin et al. · pku

Although deep learning has substantially advanced speech separation in recent years, most existing studies continue to prioritize separation quality while overlooking computational efficiency, an essential factor for low-latency speech processing in real-time applications. In this paper, we propose SepPrune, the first structured pruning framework specifically designed to compress deep speech separation models and reduce their computational cost. SepPrune begins by analyzing the computational structure of a given model to identify layers with the highest computational burden. It then introduces a differentiable masking strategy to enable gradient-driven channel selection. Based on the learned masks, SepPrune prunes redundant channels and fine-tunes the remaining parameters to recover performance. Extensive experiments demonstrate that this learnable pruning paradigm yields substantial advantages for channel pruning in speech separation models, outperforming existing methods. Notably, a model pruned with SepPrune can recover 85% of the performance of a pre-trained model (trained over hundreds of epochs) with only one epoch of fine-tuning, and achieves convergence 36$\times$ faster than training from scratch. Code is available at https://github.com/itsnotacie/SepPrune.

Junxi Chen, Junhao Dong, Xiaohua Xie

Recently, the Image Prompt Adapter (IP-Adapter) has been increasingly integrated into text-to-image diffusion models (T2I-DMs) to improve controllability. However, in this paper, we reveal that T2I-DMs equipped with the IP-Adapter (T2I-IP-DMs) enable a new jailbreak attack named the hijacking attack. We demonstrate that, by uploading imperceptible image-space adversarial examples (AEs), the adversary can hijack massive benign users to jailbreak an Image Generation Service (IGS) driven by T2I-IP-DMs and mislead the public to discredit the service provider. Worse still, the IP-Adapter's dependency on open-source image encoders reduces the knowledge required to craft AEs. Extensive experiments verify the technical feasibility of the hijacking attack. In light of the revealed threat, we investigate several existing defenses and explore combining the IP-Adapter with adversarially trained models to overcome existing defenses' limitations. Our code is available at https://github.com/fhdnskfbeuv/attackIPA.

Yuqi Li, Junhao Dong, Chuanguang Yang et al.

Vision-Language Models (VLMs) are increasingly deployed in safety-critical applications, making their adversarial robustness a crucial concern. While adversarial knowledge distillation has shown promise in transferring robustness from teacher to student models, traditional single-teacher approaches suffer from limited knowledge diversity, slow convergence, and difficulty in balancing robustness and accuracy. To address these challenges, we propose MMT-ARD: a Multimodal Multi-Teacher Adversarial Robust Distillation framework. Our key innovation is a dual-teacher knowledge fusion architecture that collaboratively optimizes clean feature preservation and robust feature enhancement. To better handle challenging adversarial examples, we introduce a dynamic weight allocation strategy based on teacher confidence, enabling adaptive focus on harder samples. Moreover, to mitigate bias among teachers, we design an adaptive sigmoid-based weighting function that balances the strength of knowledge transfer across modalities. Extensive experiments on ImageNet and zero-shot benchmarks demonstrate that MMT-ARD improves robust accuracy by +4.32% and zero-shot accuracy by +3.5% on the ViT-B-32 model, while achieving a 2.3x increase in training efficiency over traditional single-teacher methods. These results highlight the effectiveness and scalability of MMT-ARD in enhancing the adversarial robustness of multimodal large models. Our codes are available at https://github.com/itsnotacie/MMT-ARD.

Junxi Chen, Junhao Dong, Xiaohua Xie et al.

Adversarial training (AT) is considered the most effective defense against adversarial attacks. However, a recent study revealed that \(\ell_{\infty}\)-norm adversarial training (\(\ell_{\infty}\)-AT) will also induce unevenly distributed input gradients, which is called the inequality phenomenon. This phenomenon makes the \(\ell_{\infty}\)-norm adversarially trained model more vulnerable than the standard-trained model when high-attribution or randomly selected pixels are perturbed, enabling robust and practical black-box attacks against \(\ell_{\infty}\)-adversarially trained models. In this paper, we propose a simple yet effective method called Input Gradient Distillation (IGD) to release the inequality phenomenon in $\ell_{\infty}$-AT. IGD distills the standard-trained teacher model's equal decision pattern into the $\ell_{\infty}$-adversarially trained student model by aligning input gradients of the student model and the standard-trained model with the Cosine Similarity. Experiments show that IGD can mitigate the inequality phenomenon and its threats while preserving adversarial robustness. Compared to vanilla $\ell_{\infty}$-AT, IGD reduces error rates against inductive noise, inductive occlusion, random noise, and noisy images in ImageNet-C by up to 60\%, 16\%, 50\%, and 21\%, respectively. Other than empirical experiments, we also conduct a theoretical analysis to explain why releasing the inequality phenomenon can improve such robustness and discuss why the severity of the inequality phenomenon varies according to the dataset's image resolution. Our code is available at https://github.com/fhdnskfbeuv/Inuput-Gradient-Distillation

Junxi Chen, Junhao Dong, Xiaohua Xie

Recently, many studies utilized adversarial examples (AEs) to raise the cost of malicious image editing and copyright violation powered by latent diffusion models (LDMs). Despite their successes, a few have studied the surrogate model they used to generate AEs. In this paper, from the perspective of adversarial transferability, we investigate how the surrogate model's property influences the performance of AEs for LDMs. Specifically, we view the time-step sampling in the Monte-Carlo-based (MC-based) adversarial attack as selecting surrogate models. We find that the smoothness of surrogate models at different time steps differs, and we substantially improve the performance of the MC-based AEs by selecting smoother surrogate models. In the light of the theoretical framework on adversarial transferability in image classification, we also conduct a theoretical analysis to explain why smooth surrogate models can also boost AEs for LDMs.

Junhao Dong, Xinghua Qu, Z. Jane Wang et al.

Despite remarkable achievements in deep learning across various domains, its inherent vulnerability to adversarial examples still remains a critical concern for practical deployment. Adversarial training has emerged as one of the most effective defensive techniques for improving model robustness against such malicious inputs. However, existing adversarial training schemes often lead to limited generalization ability against underlying adversaries with diversity due to their overreliance on a point-by-point augmentation strategy by mapping each clean example to its adversarial counterpart during training. In addition, adversarial examples can induce significant disruptions in the statistical information w.r.t. the target model, thereby introducing substantial uncertainty and challenges to modeling the distribution of adversarial examples. To circumvent these issues, in this paper, we propose a novel uncertainty-aware distributional adversarial training method, which enforces adversary modeling by leveraging both the statistical information of adversarial examples and its corresponding uncertainty estimation, with the goal of augmenting the diversity of adversaries. Considering the potentially negative impact induced by aligning adversaries to misclassified clean examples, we also refine the alignment reference based on the statistical proximity to clean examples during adversarial training, thereby reframing adversarial training within a distribution-to-distribution matching framework interacted between the clean and adversarial domains. Furthermore, we design an introspective gradient alignment approach via matching input gradients between these domains without introducing external models. Extensive experiments across four benchmark datasets and various network architectures demonstrate that our approach achieves state-of-the-art adversarial robustness and maintains natural performance.