Zihan Zhao

Zihan Zhao, Bo Chen, Jingpiao Li et al.

Rapid developments of AI tools are expected to offer unprecedented assistance to the research of natural science including chemistry. However, neither existing unimodal task-specific specialist models nor emerging general large multimodal models (LMM) can cover the wide range of chemical data modality and task categories. To address the real demands of chemists, a cross-modal Chemical General Intelligence (CGI) system, which serves as a truly practical and useful research assistant utilizing the great potential of LMMs, is in great need. In this work, we introduce the first Cross-modal Dialogue Foundation Model for Chemistry (ChemDFM-X). Diverse multimodal data are generated from an initial modality by approximate calculations and task-specific model predictions. This strategy creates sufficient chemical training corpora, while significantly reducing excessive expense, resulting in an instruction-tuning dataset containing 7.6M data. After instruction finetuning, ChemDFM-X is evaluated on extensive experiments of different chemical tasks with various data modalities. The results demonstrate the capacity of ChemDFM-X for multimodal and inter-modal knowledge comprehension. ChemDFM-X marks a significant milestone toward aligning all modalities in chemistry, a step closer to CGI.

Haoran Qiu, Anish Biswas, Zihan Zhao et al.

Large multimodal models (LMMs) demonstrate impressive capabilities in understanding images, videos, and audio beyond text. However, efficiently serving LMMs in production environments poses significant challenges due to their complex architectures and heterogeneous characteristics across their multi-stage inference pipelines. We present the first comprehensive systems analysis of two prominent LMM architectures, decoder-only and cross-attention, across six representative open-source models, revealing key systems design implications. We also present an in-depth analysis of production LMM inference traces, uncovering unique workload characteristics, including variable, heavy-tailed request distributions and bursty traffic patterns. Based on these insights, we propose ModServe, a modular LMM serving system that decouples stages for independent optimization and adaptive scaling. ModServe dynamically reconfigures stages and handles bursty traffic with modality-aware scheduling and autoscaling to meet tail latency SLOs while minimizing costs. ModServe achieves 3.3-5.5x higher throughput (leading to 25-41.3% cost saving) while meeting SLOs on a 128-GPU cluster with production traces.

Xintong Tang, Meiru Zhang, Shang Xiao et al.

Large language models (LLMs) are often constrained by rigid reasoning processes, limiting their ability to generate creative and diverse responses. To address this, a novel framework called LADDER is proposed, combining Chain-of-Thought (CoT) reasoning, Mixture of Experts (MoE) models, and multi-dimensional up/down-sampling strategies which breaks the limitations of traditional LLMs. First, CoT reasoning guides the model through multi-step logical reasoning, expanding the semantic space and breaking the rigidity of thought. Next, MoE distributes the reasoning tasks across multiple expert modules, each focusing on specific sub-tasks. Finally, dimensionality reduction maps the reasoning outputs back to a lower-dimensional semantic space, yielding more precise and creative responses. Extensive experiments across multiple tasks demonstrate that LADDER significantly improves task completion, creativity, and fluency, generating innovative and coherent responses that outperform traditional models. Ablation studies reveal the critical roles of CoT and MoE in enhancing reasoning abilities and creative output. This work contributes to the development of more flexible and creative LLMs, capable of addressing complex and novel tasks.

Yuhan Wang, Cheng Liu, Daou Zhang et al.

In light of the mounting imperative for public security, the necessity for automated threat detection in high-risk scenarios is becoming increasingly pressing. However, existing methods generally suffer from the problems of uninterpretable inference and biased semantic understanding, which severely limits their reliability in practical deployment. In order to address the aforementioned challenges, this article proposes a threat detection method based on human-object interaction pairs (HOI-pairs), Hoi2Threat. This method is based on the fine-grained multimodal TD-Hoi dataset, enhancing the model's semantic modeling ability for key entities and their behavioral interactions by using structured HOI tags to guide language generation. Furthermore, a set of metrics is designed for the evaluation of text response quality, with the objective of systematically measuring the model's representation accuracy and comprehensibility during threat interpretation. The experimental results have demonstrated that Hoi2Threat attains substantial enhancement in several threat detection tasks, particularly in the core metrics of Correctness of Information (CoI), Behavioral Mapping Accuracy (BMA), and Threat Detailed Orientation (TDO), which are 5.08, 5.04, and 4.76, and 7.10%, 6.80%, and 2.63%, respectively, in comparison with the Gemma3 (4B). The aforementioned results provide comprehensive validation of the merits of this approach in the domains of semantic understanding, entity behavior mapping, and interpretability.

Qun Ma, Xiao Xue, Xuwen Zhang et al.

The advent of large language models (LLMs) has enabled agents to represent virtual humans in societal simulations, facilitating diverse interactions within complex social systems. However, existing LLM-based agents exhibit severe limitations in affective cognition: They fail to simulate the bounded rationality essential for bridging virtual and real-world services; They lack empirically validated integration mechanisms embedding emotions within agent decision architectures. This paper constructs an emotional cognition framework incorporating desire generation and objective management, designed to achieve emotion alignment between LLM-based agents and humans, modeling the complete decision-making process of LLM-based agents, encompassing state evolution, desire generation, objective optimization, decision generation, and action execution. This study implements the proposed framework within our proprietary multi-agent interaction environment. Experimental results demonstrate that agents governed by our framework not only exhibit behaviors congruent with their emotional states but also, in comparative assessments against other agent types, demonstrate superior ecological validity and generate decision outcomes that significantly more closely approximate human behavioral patterns.