Quynh‐Thu Le

Phuoc-Hieu Le, Quynh Le, Rang Nguyen et al.

High dynamic range (HDR) imaging is an indispensable technique in modern photography. Traditional methods focus on HDR reconstruction from multiple images, solving the core problems of image alignment, fusion, and tone mapping, yet having a perfect solution due to ghosting and other visual artifacts in the reconstruction. Recent attempts at single-image HDR reconstruction show a promising alternative: by learning to map pixel values to their irradiance using a neural network, one can bypass the align-and-merge pipeline completely yet still obtain a high-quality HDR image. In this work, we propose a weakly supervised learning method that inverts the physical image formation process for HDR reconstruction via learning to generate multiple exposures from a single image. Our neural network can invert the camera response to reconstruct pixel irradiance before synthesizing multiple exposures and hallucinating details in under- and over-exposed regions from a single input image. To train the network, we propose a representation loss, a reconstruction loss, and a perceptual loss applied on pairs of under- and over-exposure images and thus do not require HDR images for training. Our experiments show that our proposed model can effectively reconstruct HDR images. Our qualitative and quantitative results show that our method achieves state-of-the-art performance on the DrTMO dataset. Our code is available at https://github.com/VinAIResearch/single_image_hdr.

Ziyan Wang, Enmao Diao, Qi Le et al.

Reasoning LLMs (RLMs) such as OpenAI o1, DeepSeek-R1, and Qwen3 deliver strong multi-step reasoning through chain-of-thought generation, but their large model sizes and lengthy decode-time outputs make them costly to deploy and unsuitable for resource-constrained settings. To reduce computing and memory cost, pruning offers a promising solution by removing unimportant parameters. However, despite their success on standard LLMs, existing pruning methods severely damage RLMs, as even moderate sparsity (e.g., 20%) can collapse accuracy and completely disrupt the model's reasoning coherence. We begin by analyzing why existing pruning pipelines fail on reasoning LLMs and find that their brittleness largely stems from a mismatch between the calibration data, the pruning objective, and the model's decode-time reasoning behavior. Our study further shows that the most reliable calibration signal comes not from human-written labels but from the model's own self-generated reasoning traces, which more accurately reflect its inference distribution. Guided by these insights, we introduce RESP, a self-reflective structured pruning framework that aligns pruning decisions with the model's reasoning dynamics through self-generated calibration, decode-only gradient-based importance estimation, and progressive regeneration that maintains calibration fidelity as sparsity increases. Experiments on Qwen3-8B demonstrate that RESP markedly outperforms existing structured pruning methods on both GSM8K and MathQA, preserving near-dense accuracy at 20-30% sparsity and substantially mitigating performance collapse at higher sparsity levels. At 40% sparsity, RESP attains 81.3% accuracy on GSM8K and 59.6% on MathQA, surpassing the strongest baselines by 66.87% and 47%, respectively.

Praveenbalaji Rajendran, Yong Yang, Thomas R. Niedermayr et al.

Radiation therapy (RT) is one of the most effective treatments for cancer, and its success relies on the accurate delineation of targets. However, target delineation is a comprehensive medical decision that currently relies purely on manual processes by human experts. Manual delineation is time-consuming, laborious, and subject to interobserver variations. Although the advancements in artificial intelligence (AI) techniques have significantly enhanced the auto-contouring of normal tissues, accurate delineation of RT target volumes remains a challenge. In this study, we propose a visual language model-based RT target volume auto-delineation network termed Radformer. The Radformer utilizes a hierarichal vision transformer as the backbone and incorporates large language models to extract text-rich features from clinical data. We introduce a visual language attention module (VLAM) for integrating visual and linguistic features for language-aware visual encoding (LAVE). The Radformer has been evaluated on a dataset comprising 2985 patients with head-and-neck cancer who underwent RT. Metrics, including the Dice similarity coefficient (DSC), intersection over union (IOU), and 95th percentile Hausdorff distance (HD95), were used to evaluate the performance of the model quantitatively. Our results demonstrate that the Radformer has superior segmentation performance compared to other state-of-the-art models, validating its potential for adoption in RT practice.

Ziyan Wang, Enmao Diao, Qi Le et al.

Structured pruning is a practical approach to deploying large language models (LLMs) efficiently, as it yields compact, hardware-friendly architectures. However, the dominant local paradigm is task-agnostic: by optimizing layer-wise reconstruction rather than task objectives, it tends to preserve perplexity or generic zero-shot behavior but fails to capitalize on modest task-specific calibration signals, often yielding limited downstream gains. We revisit global structured pruning and present GISP-Global Iterative Structured Pruning-a post-training method that removes attention heads and MLP channels using first-order, loss-based important weights aggregated at the structure level with block-wise normalization. An iterative schedule, rather than one-shot pruning, stabilizes accuracy at higher sparsity and mitigates perplexity collapse without requiring intermediate fine-tuning; the pruning trajectory also forms nested subnetworks that support a "prune-once, deploy-many" workflow. Furthermore, because importance is defined by a model-level loss, GISP naturally supports task-specific objectives; we instantiate perplexity for language modeling and a margin-based objective for decision-style tasks. Extensive experiments show that across Llama2-7B/13B, Llama3-8B, and Mistral-0.3-7B, GISP consistently lowers WikiText-2 perplexity and improves downstream accuracy, with especially strong gains at 40-50% sparsity; on DeepSeek-R1-Distill-Llama-3-8B with GSM8K, task-aligned calibration substantially boosts exact-match accuracy.

Sheng Liu, Oscar Pastor-Serrano, Yizheng Chen et al.

Objective: Radiotherapy treatment planning is a time-consuming and potentially subjective process that requires the iterative adjustment of model parameters to balance multiple conflicting objectives. Recent advancements in frontier Artificial Intelligence (AI) models offer promising avenues for addressing the challenges in planning and clinical decision-making. This study introduces GPT-RadPlan, an automated treatment planning framework that integrates radiation oncology knowledge with the reasoning capabilities of large multi-modal models, such as GPT-4Vision (GPT-4V) from OpenAI. Approach: Via in-context learning, we incorporate clinical requirements and a few (3 in our experiments) approved clinical plans with their optimization settings, enabling GPT-4V to acquire treatment planning domain knowledge. The resulting GPT-RadPlan system is integrated into our in-house inverse treatment planning system through an application programming interface (API). For a given patient, GPT-RadPlan acts as both plan evaluator and planner, first assessing dose distributions and dose-volume histograms (DVHs), and then providing textual feedback on how to improve the plan to match the physician's requirements. In this manner, GPT-RadPlan iteratively refines the plan by adjusting planning parameters, such as weights and dose objectives, based on its suggestions. Main results: The efficacy of the automated planning system is showcased across 17 prostate cancer and 13 head and neck cancer VMAT plans with prescribed doses of 70.2 Gy and 72 Gy, respectively, where we compared GPT-RadPlan results to clinical plans produced by human experts. In all cases, GPT-RadPlan either outperformed or matched the clinical plans, demonstrating superior target coverage and reducing organ-at-risk doses by 5 Gy on average (15 percent for prostate and 10-15 percent for head and neck).