Rui Yin

Lingyao Li, Deyi Li, Chen Chen et al.

Large language models (LLMs) are increasingly deployed across healthcare applications, including clinical documentation, diagnostic reasoning, medicine recommendation, and medical education. Their outputs are largely unstructured clinical text, which is difficult to reliably evaluate at scale. LLM-as-a-Judge, in which an LLM evaluates another system's output against task-specific criteria, offers a scalable alternative and is increasingly used in clinical evaluation, yet its validity in healthcare remains underexamined. Existing reviews focus on general-purpose LLM evaluation or on risk framework, rather than systematically characterizing how LLM-as-a-Judge is applied in healthcare and how well their judgments align with human experts. We therefore conduct a PRISMA-guided comprehensive review of LLM-as-a-Judge applications in healthcare, searching five databases for studies published between January 2023 and February 2026. After screening 541 records, 134 studies meet the eligibility and are coded by health scenario, judge configuration, technical approach, and validation design. LLM-as-a-Judge is concentrated in clinical decision support, clinical natural language processing (NLP), medical knowledge and question answering (QA), and medical communication. OpenAI models are the most frequently used judges, and prompt engineering appears in nearly all studies, with ensemble, multi-agent, and retrieval-augmented designs as common extensions. Among studies reporting human validation, LLM judges often show moderate to strong alignment with expert judgments, although reliability varies substantially across tasks. Overall, this review positions LLM-as-a-Judge as a promising framework for scalable healthcare AI evaluation, while emphasizing that its clinical value depends on model design and rigorous validation.

Rui Yin, Tianxu Han, Naen Xu et al.

Safety-aligned large language models (LLMs) are increasingly deployed in real-world pipelines, yet this deployment also enlarges the supply-chain attack surface: adversaries can distribute backdoored checkpoints that behave normally under standard evaluation but jailbreak when a hidden trigger is present. Recent post-hoc weight-editing methods offer an efficient approach to injecting such backdoors by directly modifying model weights to map a trigger to an attacker-specified response. However, existing methods typically optimize a token-level mapping that forces an affirmative prefix (e.g., ``Sure''), which does not guarantee sustained harmful output -- the model may begin with apparent agreement yet revert to safety-aligned refusal within a few decoding steps. We address this reliability gap by shifting the backdoor objective from surface tokens to internal representations. We extract a steering vector that captures the difference between compliant and refusal behaviors, and compile it into a persistent weight modification that activates only when the trigger is present. To preserve stealthiness and benign utility, we impose a null-space constraint so that the injected edit remains dormant on clean inputs. The method is efficient, requiring only a small set of examples and admitting a closed-form solution. Across multiple safety-aligned LLMs and jailbreak benchmarks, our method achieves high triggered attack success while maintaining non-triggered safety and general utility.

Sheng Lu, Hao Chen, Rui Yin et al.

Recent vision-language models (VLMs) have shown strong generalization and multimodal reasoning abilities in natural domains. However, their application to medical diagnosis remains limited by the lack of comprehensive and structured datasets that capture real clinical workflows. To advance the development of VLMs for clinical applications, particularly in gastric cancer, we introduce Gastric-X, a large-scale multimodal benchmark for gastric cancer analysis providing 1.7K cases. Each case in Gastric-X includes paired resting and dynamic CT scans, endoscopic image, a set of structured biochemical indicators, expert-authored diagnostic notes, and bounding box annotations of tumor regions, reflecting realistic clinical conditions. We systematically examine the capability of recent VLMs on five core tasks: Visual Question Answering (VQA), report generation, cross-modal retrieval, disease classification, and lesion localization. These tasks simulate critical stages of clinical workflow, from visual understanding and reasoning to multimodal decision support. Through this evaluation, we aim not only to assess model performance but also to probe the nature of VLM understanding: Can current VLMs meaningfully correlate biochemical signals with spatial tumor features and textual reports? We envision Gastric-X as a step toward aligning machine intelligence with the cognitive and evidential reasoning processes of physicians, and as a resource to inspire the development of next-generation medical VLMs.

Rui Yin, Yulun Zhang, Zherong Pan et al.

Two-view pose estimation is essential for map-free visual relocalization and object pose tracking tasks. However, traditional matching methods suffer from time-consuming robust estimators, while deep learning-based pose regressors only cater to camera-to-world pose estimation, lacking generalizability to different image sizes and camera intrinsics. In this paper, we propose SRPose, a sparse keypoint-based framework for two-view relative pose estimation in camera-to-world and object-to-camera scenarios. SRPose consists of a sparse keypoint detector, an intrinsic-calibration position encoder, and promptable prior knowledge-guided attention layers. Given two RGB images of a fixed scene or a moving object, SRPose estimates the relative camera or 6D object pose transformation. Extensive experiments demonstrate that SRPose achieves competitive or superior performance compared to state-of-the-art methods in terms of accuracy and speed, showing generalizability to both scenarios. It is robust to different image sizes and camera intrinsics, and can be deployed with low computing resources.

Xuanzhao Dong, Wenhui Zhu, Hao Wang et al.

Medical question answering (QA) is a reasoning-intensive task that remains challenging for large language models (LLMs) due to hallucinations and outdated domain knowledge. Retrieval-Augmented Generation (RAG) provides a promising post-training solution by leveraging external knowledge. However, existing medical RAG systems suffer from two key limitations: (1) a lack of modeling for human-like reasoning behaviors during information retrieval, and (2) reliance on suboptimal medical corpora, which often results in the retrieval of irrelevant or noisy snippets. To overcome these challenges, we propose Discuss-RAG, a plug-and-play module designed to enhance the medical QA RAG system through collaborative agent-based reasoning. Our method introduces a summarizer agent that orchestrates a team of medical experts to emulate multi-turn brainstorming, thereby improving the relevance of retrieved content. Additionally, a decision-making agent evaluates the retrieved snippets before their final integration. Experimental results on four benchmark medical QA datasets show that Discuss-RAG consistently outperforms MedRAG, especially significantly improving answer accuracy by up to 16.67% on BioASQ and 12.20% on PubMedQA. The code is available at: https://github.com/LLM-VLM-GSL/Discuss-RAG.

Qiang Yang, Xiuying Chen, Changsheng Ma et al.

The global impact of the COVID-19 pandemic has highlighted the need for a comprehensive understanding of public sentiment and reactions. Despite the availability of numerous public datasets on COVID-19, some reaching volumes of up to 100 billion data points, challenges persist regarding the availability of labeled data and the presence of coarse-grained or inappropriate sentiment labels. In this paper, we introduce SenWave, a novel fine-grained multi-language sentiment analysis dataset specifically designed for analyzing COVID-19 tweets, featuring ten sentiment categories across five languages. The dataset comprises 10,000 annotated tweets each in English and Arabic, along with 30,000 translated tweets in Spanish, French, and Italian, derived from English tweets. Additionally, it includes over 105 million unlabeled tweets collected during various COVID-19 waves. To enable accurate fine-grained sentiment classification, we fine-tuned pre-trained transformer-based language models using the labeled tweets. Our study provides an in-depth analysis of the evolving emotional landscape across languages, countries, and topics, revealing significant insights over time. Furthermore, we assess the compatibility of our dataset with ChatGPT, demonstrating its robustness and versatility in various applications. Our dataset and accompanying code are publicly accessible on the repository\footnote{https://github.com/gitdevqiang/SenWave}. We anticipate that this work will foster further exploration into fine-grained sentiment analysis for complex events within the NLP community, promoting more nuanced understanding and research innovations.

Hao Chen, Rui Yin, Yifan Chen et al.

Understanding disease progression is a central clinical challenge with direct implications for early diagnosis and personalized treatment. While recent generative approaches have attempted to model progression, key mismatches remain: disease dynamics are inherently continuous and monotonic, yet latent representations are often scattered, lacking semantic structure, and diffusion-based models disrupt continuity with random denoising process. In this work, we propose to treat the disease dynamic as a velocity field and leverage Flow Matching (FM) to align the temporal evolution of patient data. Unlike prior methods, it captures the intrinsic dynamic of disease, making the progression more interpretable. However, a key challenge remains: in latent space, Auto-Encoders (AEs) do not guarantee alignment across patients or correlation with clinical-severity indicators (e.g., age and disease conditions). To address this, we propose to learn patient-specific latent alignment, which enforces patient trajectories to lie along a specific axis, with magnitude increasing monotonically with disease severity. This leads to a consistent and semantically meaningful latent space. Together, we present $Δ$-LFM, a framework for modeling patient-specific latent progression with flow matching. Across three longitudinal MRI benchmarks, $Δ$-LFM demonstrates strong empirical performance and, more importantly, offers a new framework for interpreting and visualizing disease dynamics.

Xianzhe Meng, Qiangsheng Zeng, Ling Luo et al.

Training stability is typically regarded as a prerequisite for reliable optimization in large language models. In this work, we analyze how stabilizing training dynamics affects the induced generation distribution. We show that under standard maximum likelihood training, stable parameter trajectories lead stationary solutions to approximately minimize the forward KL divergence to the empirical distribution, while implicitly reducing generative entropy. As a consequence, the learned model can concentrate probability mass on a limited subset of empirical modes, exhibiting systematic degeneration despite smooth loss convergence. We empirically validate this effect using a controlled feedback-based training framework that stabilizes internal generation statistics, observing consistent low-entropy outputs and repetitive behavior across architectures and random seeds. It indicates that optimization stability and generative expressivity are not inherently aligned, and that stability alone is an insufficient indicator of generative quality.

Xiaoxuan Liang, Wuyang Zhang, Hong Zhou et al.

3D Human Mesh Reconstruction (HMR) from 2D RGB images faces challenges in environments with poor lighting, privacy concerns, or occlusions. These weaknesses of RGB imaging can be complemented by acoustic signals, which are widely available, easy to deploy, and capable of penetrating obstacles. However, no existing methods effectively combine acoustic signals with RGB data for robust 3D HMR. The primary challenges include the low-resolution images generated by acoustic signals and the lack of dedicated processing backbones. We introduce SonicMesh, a novel approach combining acoustic signals with RGB images to reconstruct 3D human mesh. To address the challenges of low resolution and the absence of dedicated processing backbones in images generated by acoustic signals, we modify an existing method, HRNet, for effective feature extraction. We also integrate a universal feature embedding technique to enhance the precision of cross-dimensional feature alignment, enabling SonicMesh to achieve high accuracy. Experimental results demonstrate that SonicMesh accurately reconstructs 3D human mesh in challenging environments such as occlusions, non-line-of-sight scenarios, and poor lighting.

Rui Yin, Haotong Qin, Yulun Zhang et al.

Dense prediction is a critical task in computer vision. However, previous methods often require extensive computational resources, which hinders their real-world application. In this paper, we propose BiDense, a generalized binary neural network (BNN) designed for efficient and accurate dense prediction tasks. BiDense incorporates two key techniques: the Distribution-adaptive Binarizer (DAB) and the Channel-adaptive Full-precision Bypass (CFB). The DAB adaptively calculates thresholds and scaling factors for binarization, effectively retaining more information within BNNs. Meanwhile, the CFB facilitates full-precision bypassing for binary convolutional layers undergoing various channel size transformations, which enhances the propagation of real-valued signals and minimizes information loss. By leveraging these techniques, BiDense preserves more real-valued information, enabling more accurate and detailed dense predictions in BNNs. Extensive experiments demonstrate that our framework achieves performance levels comparable to full-precision models while significantly reducing memory usage and computational costs.

Hao Chen, Hongrun Zhang, U Wang Chan et al.

Single domain generalization aims to address the challenge of out-of-distribution generalization problem with only one source domain available. Feature distanglement is a classic solution to this purpose, where the extracted task-related feature is presumed to be resilient to domain shift. However, the absence of references from other domains in a single-domain scenario poses significant uncertainty in feature disentanglement (ill-posedness). In this paper, we propose a new framework, named \textit{Domain Game}, to perform better feature distangling for medical image segmentation, based on the observation that diagnostic relevant features are more sensitive to geometric transformations, whilist domain-specific features probably will remain invariant to such operations. In domain game, a set of randomly transformed images derived from a singular source image is strategically encoded into two separate feature sets to represent diagnostic features and domain-specific features, respectively, and we apply forces to pull or repel them in the feature space, accordingly. Results from cross-site test domain evaluation showcase approximately an ~11.8% performance boost in prostate segmentation and around ~10.5% in brain tumor segmentation compared to the second-best method.

Rui Yin, Yineng Shen, Huawei Zhu et al.

Mobile edge computing (MEC) deployment in a multi-robot cooperation (MRC) system is an effective way to accomplish the tasks in terms of energy consumption and implementation latency. However, the computation and communication resources need to be considered jointly to fully exploit the advantages brought by the MEC technology. In this paper, the scenario where multi robots cooperate to accomplish the time-critical tasks is studied, where an intelligent master robot (MR) acts as an edge server to provide services to multiple slave robots (SRs) and the SRs are responsible for the environment sensing and data collection. To save energy and prolong the function time of the system, two schemes are proposed to optimize the computation and communication resources, respectively. In the first scheme, the energy consumption of SRs is minimized and balanced while guaranteeing that the tasks are accomplished under a time constraint. In the second scheme, not only the energy consumption, but also the remaining energies of the SRs are considered to enhance the robustness of the system. Through the analysis and numerical simulations, we demonstrate that even though the first policy may guarantee the minimization on the total SRs' energy consumption, the function time of MRC system by the second scheme is longer than that by the first one.

Zhuoyi Lin, Lei Feng, Xingzhi Guo et al.

Representation learning-based recommendation models play a dominant role among recommendation techniques. However, most of the existing methods assume both historical interactions and embedding dimensions are independent of each other, and thus regrettably ignore the high-order interaction information among historical interactions and embedding dimensions. In this paper, we propose a novel representation learning-based model called COMET (COnvolutional diMEnsion inTeraction), which simultaneously models the high-order interaction patterns among historical interactions and embedding dimensions. To be specific, COMET stacks the embeddings of historical interactions horizontally at first, which results in two "embedding maps". In this way, internal interactions and dimensional interactions can be exploited by convolutional neural networks (CNN) with kernels of different sizes simultaneously. A fully-connected multi-layer perceptron (MLP) is then applied to obtain two interaction vectors. Lastly, the representations of users and items are enriched by the learnt interaction vectors, which can further be used to produce the final prediction. Extensive experiments and ablation studies on various public implicit feedback datasets clearly demonstrate the effectiveness and rationality of our proposed method.

Zhuoyi Lin, Lei Feng, Rui Yin et al.

Graph-based recommendation models work well for top-N recommender systems due to their capability to capture the potential relationships between entities. However, most of the existing methods only construct a single global item graph shared by all the users and regrettably ignore the diverse tastes between different user groups. Inspired by the success of local models for recommendation, this paper provides the first attempt to investigate multiple local item graphs along with a global item graph for graph-based recommendation models. We argue that recommendation on global and local graphs outperforms that on a single global graph or multiple local graphs. Specifically, we propose a novel graph-based recommendation model named GLIMG (Global and Local IteM Graphs), which simultaneously captures both the global and local user tastes. By integrating the global and local graphs into an adapted semi-supervised learning model, users' preferences on items are propagated globally and locally. Extensive experimental results on real-world datasets show that our proposed method consistently outperforms the state-of-the art counterparts on the top-N recommendation task.