Yiru Zhou

Ziyun Yu, Yiru Zhou, Chen Zhao et al.

Using Large Language Models (LLMs) to simulate user opinions has received growing attention. Yet LLMs, especially trained with reinforcement learning from human feedback (RLHF), are known to exhibit biases toward dominant viewpoints, raising concerns about their ability to represent users from diverse demographic and cultural backgrounds. In this work, we examine the extent to which LLMs can simulate human responses to cross-domain survey questions through direct prompting and chain-of-thought prompting. We further propose a claim diversification method CLAIMSIM, which elicits viewpoints from LLM parametric knowledge as contextual input. Experiments on the survey question answering task indicate that, while CLAIMSIM produces more diverse responses, both approaches struggle to accurately simulate users. Further analysis reveals two key limitations: (1) LLMs tend to maintain fixed viewpoints across varying demographic features, and generate single-perspective claims; and (2) when presented with conflicting claims, LLMs struggle to reason over nuanced differences among demographic features, limiting their ability to adapt responses to specific user profiles.

Nishchal Sapkota, Yejia Zhang, Sirui Li et al.

Male infertility accounts for about one-third of global infertility cases. Manual assessment of sperm abnormalities through head morphology analysis encounters issues of observer variability and diagnostic discrepancies among experts. Its alternative, Computer-Assisted Semen Analysis (CASA), suffers from low-quality sperm images, small datasets, and noisy class labels. We propose a new approach for sperm head morphology classification, called SHMC-Net, which uses segmentation masks of sperm heads to guide the morphology classification of sperm images. SHMC-Net generates reliable segmentation masks using image priors, refines object boundaries with an efficient graph-based method, and trains an image network with sperm head crops and a mask network with the corresponding masks. In the intermediate stages of the networks, image and mask features are fused with a fusion scheme to better learn morphological features. To handle noisy class labels and regularize training on small datasets, SHMC-Net applies Soft Mixup to combine mixup augmentation and a loss function. We achieve state-of-the-art results on SCIAN and HuSHeM datasets, outperforming methods that use additional pre-training or costly ensembling techniques.

Yejia Zhang, Jingjing Zhang, Xiaomin Zha et al.

With rising male infertility, sperm head morphology classification becomes critical for accurate and timely clinical diagnosis. Recent deep learning (DL) morphology analysis methods achieve promising benchmark results, but leave performance and robustness on the table by relying on limited and possibly noisy class labels. To address this, we introduce a new DL training framework that leverages anatomical and image priors from human sperm microscopy crops to extract useful features without additional labeling cost. Our core idea is to distill sperm head information with reliably-generated pseudo-masks and unsupervised spatial prediction tasks. The predicted foreground masks from this distillation step are then leveraged to regularize and reduce image and label noise in the tuning stage. We evaluate our new approach on two public sperm datasets and achieve state-of-the-art performances (e.g. 65.9% SCIAN accuracy and 96.5% HuSHeM accuracy).