Wenyu Song

LG
h-index10
4papers
740citations
Novelty53%
AI Score28

4 Papers

LGJan 30, 2024
Heterogeneous treatment effect estimation with subpopulation identification for personalized medicine in opioid use disorder

Seungyeon Lee, Ruoqi Liu, Wenyu Song et al.

Deep learning models have demonstrated promising results in estimating treatment effects (TEE). However, most of them overlook the variations in treatment outcomes among subgroups with distinct characteristics. This limitation hinders their ability to provide accurate estimations and treatment recommendations for specific subgroups. In this study, we introduce a novel neural network-based framework, named SubgroupTE, which incorporates subgroup identification and treatment effect estimation. SubgroupTE identifies diverse subgroups and simultaneously estimates treatment effects for each subgroup, improving the treatment effect estimation by considering the heterogeneity of treatment responses. Comparative experiments on synthetic data show that SubgroupTE outperforms existing models in treatment effect estimation. Furthermore, experiments on a real-world dataset related to opioid use disorder (OUD) demonstrate the potential of our approach to enhance personalized treatment recommendations for OUD patients.

LGJan 22, 2024
SubgroupTE: Advancing Treatment Effect Estimation with Subgroup Identification

Seungyeon Lee, Ruoqi Liu, Wenyu Song et al.

Precise estimation of treatment effects is crucial for evaluating intervention effectiveness. While deep learning models have exhibited promising performance in learning counterfactual representations for treatment effect estimation (TEE), a major limitation in most of these models is that they treat the entire population as a homogeneous group, overlooking the diversity of treatment effects across potential subgroups that have varying treatment effects. This limitation restricts the ability to precisely estimate treatment effects and provide subgroup-specific treatment recommendations. In this paper, we propose a novel treatment effect estimation model, named SubgroupTE, which incorporates subgroup identification in TEE. SubgroupTE identifies heterogeneous subgroups with different treatment responses and more precisely estimates treatment effects by considering subgroup-specific causal effects. In addition, SubgroupTE iteratively optimizes subgrouping and treatment effect estimation networks to enhance both estimation and subgroup identification. Comprehensive experiments on the synthetic and semi-synthetic datasets exhibit the outstanding performance of SubgroupTE compared with the state-of-the-art models on treatment effect estimation. Additionally, a real-world study demonstrates the capabilities of SubgroupTE in enhancing personalized treatment recommendations for patients with opioid use disorder (OUD) by advancing treatment effect estimation with subgroup identification.

CLJul 7, 2021
EchoEA: Echo Information between Entities and Relations for Entity Alignment

Xueyuan Lin, Haihong E, Wenyu Song et al.

Entity alignment (EA) plays an important role in automatically integrating knowledge graphs (KGs) from multiple sources. Recent approaches based on Graph Neural Network (GNN) obtain entity representation from relation information and have achieved promising results. Besides, more and more methods introduce semi-supervision to ask for more labeled training data. However, two challenges still exist in GNN-based EA methods: (1) Deeper GNN Encoder: The GNN encoder of current methods has limited depth (usually 2-layers). (2) Low-quality Bootstrapping: The generated semi-supervised data is of low quality. In this paper, we propose a novel framework, Echo Entity Alignment (EchoEA), which leverages 4-levels self-attention mechanism to spread entity information to relations and echo back to entities. Furthermore, we propose attribute-combined bi-directional global-filtered strategy (ABGS) to improve bootstrapping, reduce false samples and generate high-quality training data. The experimental results on three real-world cross-lingual datasets are stable at around 96\% at hits@1 on average, showing that our approach not only significantly outperforms the state-of-the-art GNN-based methods, but also is universal and transferable for existing EA methods.

AISep 30, 2020
RTFE: A Recursive Temporal Fact Embedding Framework for Temporal Knowledge Graph Completion

Youri Xu, E Haihong, Meina Song et al.

Static knowledge graph (SKG) embedding (SKGE) has been studied intensively in the past years. Recently, temporal knowledge graph (TKG) embedding (TKGE) has emerged. In this paper, we propose a Recursive Temporal Fact Embedding (RTFE) framework to transplant SKGE models to TKGs and to enhance the performance of existing TKGE models for TKG completion. Different from previous work which ignores the continuity of states of TKG in time evolution, we treat the sequence of graphs as a Markov chain, which transitions from the previous state to the next state. RTFE takes the SKGE to initialize the embeddings of TKG. Then it recursively tracks the state transition of TKG by passing updated parameters/features between timestamps. Specifically, at each timestamp, we approximate the state transition as the gradient update process. Since RTFE learns each timestamp recursively, it can naturally transit to future timestamps. Experiments on five TKG datasets show the effectiveness of RTFE.