Yuanhao Zou

Tianxingjian Ding, Yuanhao Zou, Chen Chen et al.

Clinical decision-making in oncology requires predicting dynamic disease evolution, a task current static AI predictors cannot perform. While world models (WMs) offer a paradigm for generative prediction, existing medical applications remain limited. Existing methods often rely on stochastic diffusion models, focusing on visual reconstruction rather than causal, physiological transitions. Furthermore, in medical domain, models like MeWM typically ignore patient-specific temporal and clinical contexts and lack a feedback mechanism to link predictions to treatment decisions. To address these gaps, we introduce CLARITY, a medical world model that forecasts disease evolution directly within a structured latent space. It explicitly integrates time intervals (temporal context) and patient-specific data (clinical context) to model treatment-conditioned progression as a smooth, interpretable trajectory, and thus generate physiologically faithful, individualized treatment plans. Finally, CLARITY introduces a novel prediction-to-decision framework, translating latent rollouts into transparent, actionable recommendations. CLARITY demonstrates state-of-the-art performance in treatment planning. On the MU-Glioma-Post dataset, our approach outperforms recent MeWM by 12\%, and significantly surpasses all other medical-specific large language models.

Shengji Jin, Yuanhao Zou, Victor Zhu et al.

While Multimodal Large Language Models (MLLMs) have advanced Video Temporal Grounding (VTG), existing methods often couple output paradigms with different backbones, datasets, and training protocols. This makes it challenging to isolate the specific impact of the output design. Additionally, as VTG systems are increasingly considered for resource-constrained edge deployment, the trade-off between output formulation and system-level efficiency requires systematic investigation. In this paper, we present a controlled empirical study comparing three dominant VTG output paradigms: Text Numeral Generation, Temporal Token Generation, and Continuous Temporal Decoding. We evaluate these paradigms across identical compact VLMs (SmolVLM2, FastVLM, and Molmo2) using consistent datasets and LoRA fine-tuning protocols. Evaluations on Charades-STA, QVHighlights, and YouCook2 measure both localization accuracy and system efficiency, including inference latency, training throughput, and parameter overhead. Our results demonstrate that the choice of output formulation significantly affects both grounding accuracy and computational cost, independent of model scale. Specifically, the continuous distribution paradigm consistently achieves the most favorable efficiency-accuracy trade-off on the Pareto frontier, delivering robust localization with minimal latency overhead. These findings provide objective empirical guidelines for designing efficient, deployment-ready VTG systems.

Yuanhao Zou, Zhaozheng Yin

Medical Visual Question Answering (Med-VQA) is a challenging task that requires a deep understanding of both medical images and textual questions. Although recent works leveraging Medical Vision-Language Pre-training (Med-VLP) have shown strong performance on the Med-VQA task, there is still no unified solution for modality alignment, and the issue of hard negatives remains under-explored. Additionally, commonly used knowledge fusion techniques for Med-VQA may introduce irrelevant information. In this work, we propose a framework to address these challenges through three key contributions: (1) a unified solution for heterogeneous modality alignments across multiple levels, modalities, views, and stages, leveraging methods like contrastive learning and optimal transport theory; (2) a hard negative mining method that employs soft labels for multi-modality alignments and enforces the hard negative pair discrimination; and (3) a Gated Cross-Attention Module for Med-VQA that integrates the answer vocabulary as prior knowledge and selects relevant information from it. Our framework outperforms the previous state-of-the-art on widely used Med-VQA datasets like RAD-VQA, SLAKE, PathVQA and VQA-2019.

Yuanhao Zou, Shengji Jin, Andong Deng et al.

Effectively applying Vision-Language Models (VLMs) to Video Question Answering (VideoQA) hinges on selecting a concise yet comprehensive set of frames, as processing entire videos is computationally infeasible. However, current frame selection methods face a critical trade-off: approaches relying on lightweight similarity models, such as CLIP, often fail to capture the nuances of complex queries, resulting in inaccurate similarity scores that cannot reflect the authentic query-frame relevance, which further undermines frame selection. Meanwhile, methods that leverage a VLM for deeper analysis achieve higher accuracy but incur prohibitive computational costs. To address these limitations, we propose A.I.R., a training-free approach for Adaptive, Iterative, and Reasoning-based frame selection. We leverage a powerful VLM to perform deep, semantic analysis on complex queries, and this analysis is deployed within a cost-effective iterative loop that processes only a small batch of the most high-potential frames at a time. Extensive experiments on various VideoQA benchmarks demonstrate that our approach outperforms existing frame selection methods, significantly boosts the performance of the foundation VLM, and achieves substantial gains in computational efficiency over other VLM-based techniques.