Mạnh Hùng Nguyễn

h-index8
2papers
261citations

2 Papers

4.1LGNov 13, 2025
Uncertainty-Guided Checkpoint Selection for Reinforcement Finetuning of Large Language Models

Manh Nguyen, Dung Nguyen, Dai Do et al.

Reinforcement learning (RL) finetuning is crucial to aligning large language models (LLMs), but the process is notoriously unstable and exhibits high variance across model checkpoints. In practice, selecting the best checkpoint is challenging: evaluating checkpoints on the validation set during training is computationally expensive and requires a good validation set, while relying on the final checkpoint provides no guarantee of good performance. We introduce an uncertainty-guided approach for checkpoint selection (UGCS) that avoids these pitfalls. Our method identifies hard question-answer pairs using per-sample uncertainty and ranks checkpoints by how well they handle these challenging cases. By averaging the rewards of the top-uncertain samples over a short training window, our method produces a stable and discriminative signal without additional forward passes or significant computation overhead. Experiments across three datasets and three LLMs demonstrate that it consistently identifies checkpoints with stronger generalization, outperforming traditional strategies such as relying on training or validation performance. These results highlight that models solving their hardest tasks with low uncertainty are the most reliable overall.

6.2CVJan 3, 2025Code
Bridging Classification and Segmentation in Osteosarcoma Assessment via Foundation and Discrete Diffusion Models

Manh Duong Nguyen, Dac Thai Nguyen, Trung Viet Nguyen et al.

Osteosarcoma, the most common primary bone cancer, often requires accurate necrosis assessment from whole slide images (WSIs) for effective treatment planning and prognosis. However, manual assessments are subjective and prone to variability. In response, we introduce FDDM, a novel framework bridging the gap between patch classification and region-based segmentation. FDDM operates in two stages: patch-based classification, followed by region-based refinement, enabling cross-patch information intergation. Leveraging a newly curated dataset of osteosarcoma images, FDDM demonstrates superior segmentation performance, achieving up to a 10% improvement mIOU and a 32.12% enhancement in necrosis rate estimation over state-of-the-art methods. This framework sets a new benchmark in osteosarcoma assessment, highlighting the potential of foundation models and diffusion-based refinements in complex medical imaging tasks.