Yu Zhang

Shuang Li, Yibing Wang, Jian Gao et al.

High-quality three-dimensional (3D) photoacoustic imaging (PAI) is gaining increasing attention in clinical applications. To address the challenges of limited space and high costs, irregular geometric transducer arrays that conform to specific imaging regions are promising for achieving high-quality 3D PAI with fewer transducers. However, traditional iterative reconstruction algorithms struggle with irregular array configurations, suffering from high computational complexity, substantial memory requirements, and lengthy reconstruction times. In this work, we introduce SlingBAG Pro, an advanced reconstruction algorithm based on the point cloud iteration concept of the Sliding ball adaptive growth (SlingBAG) method, while extending its compatibility to arbitrary array geometries. SlingBAG Pro maintains high reconstruction quality, reduces the number of required transducers, and employs a hierarchical optimization strategy that combines zero-gradient filtering with progressively increased temporal sampling rates during iteration. This strategy rapidly removes redundant spatial point clouds, accelerates convergence, and significantly shortens overall reconstruction time. Compared to the original SlingBAG algorithm, SlingBAG Pro achieves up to a 2.2-fold speed improvement in point cloud-based 3D PA reconstruction under irregular array geometries. The proposed method is validated through both simulation and in vivo mouse experiments, and the source code is publicly available at https://github.com/JaegerCQ/SlingBAG_Pro.

Jeyun Lee, Junhyoung Lee, Wonbin Kweon et al.

Adapting general-domain retrievers to scientific domains is challenging due to the scarcity of large-scale domain-specific relevance annotations and the substantial mismatch in vocabulary and information needs. Recent approaches address these issues through two independent directions that leverage large language models (LLMs): (1) generating synthetic queries for fine-tuning, and (2) generating auxiliary contexts to support relevance matching. However, both directions overlook the diverse academic concepts embedded within scientific documents, often producing redundant or conceptually narrow queries and contexts. To address this limitation, we introduce an academic concept index, which extracts key concepts from papers and organizes them guided by an academic taxonomy. This structured index serves as a foundation for improving both directions. First, we enhance the synthetic query generation with concept coverage-based generation (CCQGen), which adaptively conditions LLMs on uncovered concepts to generate complementary queries with broader concept coverage. Second, we strengthen the context augmentation with concept-focused auxiliary contexts (CCExpand), which leverages a set of document snippets that serve as concise responses to the concept-aware CCQGen queries. Extensive experiments show that incorporating the academic concept index into both query generation and context augmentation leads to higher-quality queries, better conceptual alignment, and improved retrieval performance.

Yihe Wang, Zhiqiao Kang, Bohan Chen et al.

Event-related potential (ERP), a specialized paradigm of electroencephalographic (EEG), reflects neurological responses to external stimuli or events, generally associated with the brain's processing of specific cognitive tasks. ERP plays a critical role in cognitive analysis, the detection of neurological diseases, and the assessment of psychological states. Recent years have seen substantial advances in deep learning-based methods for spontaneous EEG and other non-time-locked task-related EEG signals. However, their effectiveness on ERP data remains underexplored, and many existing ERP studies still rely heavily on manually extracted features. In this paper, we conduct a comprehensive benchmark study that systematically compares traditional manual features (followed by a linear classifier), deep learning models, and pre-trained EEG foundation models for ERP analysis. We establish a unified data preprocessing and training pipeline and evaluate these approaches on two representative tasks, ERP stimulus classification and ERP-based brain disease detection, across 12 publicly available datasets. Furthermore, we investigate various token-embedding strategies within advanced Transformer architectures to identify embedding designs that better suit ERP data. Our study provides a landmark framework to guide method selection and tailored model design for future ERP analysis. The code is available at https://github.com/DL4mHealth/ERP-Benchmark

Rong Zhou, Dongping Chen, Zihan Jia et al.

Digital twins, as precise digital representations of physical systems, have evolved from passive simulation tools into intelligent and autonomous entities through the integration of artificial intelligence technologies. This paper presents a unified four-stage framework that systematically characterizes AI integration across the digital twin lifecycle, spanning modeling, mirroring, intervention, and autonomous management. By synthesizing existing technologies and practices, we distill a unified four-stage framework that systematically characterizes how AI methodologies are embedded across the digital twin lifecycle: (1) modeling the physical twin through physics-based and physics-informed AI approaches, (2) mirroring the physical system into a digital twin with real-time synchronization, (3) intervening in the physical twin through predictive modeling, anomaly detection, and optimization strategies, and (4) achieving autonomous management through large language models, foundation models, and intelligent agents. We analyze the synergy between physics-based modeling and data-driven learning, highlighting the shift from traditional numerical solvers to physics-informed and foundation models for physical systems. Furthermore, we examine how generative AI technologies, including large language models and generative world models, transform digital twins into proactive and self-improving cognitive systems capable of reasoning, communication, and creative scenario generation. Through a cross-domain review spanning eleven application domains, including healthcare, aerospace, smart manufacturing, robotics, and smart cities, we identify common challenges related to scalability, explainability, and trustworthiness, and outline directions for responsible AI-driven digital twin systems.